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Biomedical and Tissue Engineering Research Group

Overview of Group Research Activities

The Biomedical and Tissue Engineering Research Group aims to bridge the gap between basic science research and its clinical application in the field of bone induction (stimulation of bone formation) and dental biomaterials.

Members of this research group come from various disciplines and specialties, including dental materials science, orthodontics, paediatric dentistry, oral and maxillofacial surgery, and oral radiology. Many members of the group have earned an international reputation. The group is supported by up-to-date laboratory and operative equipment, as well as extensive human resources.

Our principal research strength:

  • Growth factors regulating osteogenesis (bone formation)
  • Bone and tooth tissue engineering with stem cells (unspecialised cells with the potential to develop into specific cell types)
  • Bone induction (stimulation of bone formation) using traditional Chinese medicines
  • Jaw reconstruction with microvascular prefabricated flaps (sections of own tissue containing fine blood vessels)
  • Enamel- and dentine-bonding agents (non-metal tooth-filling materials)
  • Biodegradation of the resin-dentine bond (longevity of plastic tooth-filling materials)
  • Distraction osteogenesis of the cranio-maxillofacial region (controlled step-wise movement and healing of surgically created fractures in bones of the skull, jaw, and face)
  • Dental biomaterials, as well as tissue-engineered scaffolds (artificial nets that hold and support cells)
  • 3-dimensional facial imaging, as well as cephalometry (measurements of face and head features)
  • Healing of dental implants with nano-coating (a very thin layer of very small molecules)
  • Oral cancer
  • 3-dimensional head and neck imaging with magnetic resonance imaging (MRI) and computed tomography (scanning using magnets and X-rays, respectively)
  • Brain function mapping using functional MRI (scanning using magnets to track changes in blood flow)


Our vision:
To be Asia's leading research group in Biomedical and Tissue Engineering of the oral and maxillofacial (mouth, jaw, and face) region.

Action Plan for 2008-2012:

  1. To encourage and assist our members to integrate into the new HKU Strategic Research Themes
  2. To co-organise at least one regional or international research conference with other faculties of HKU, other universities in Hong Kong, China, and the world
  3. To appoint an international reputable biomedical engineering advisor to assist members in refining their research grant proposals and to facilitate international exchanges
  4. To foster research in multidisciplinary teams and facilitate collaborative grant applications among members and with other research groups
  5. To encourage members to apply for research funding from the Hong Kong Research Grants Council and external organisations, and to assist them in refining their grant proposals
  6. To develop a research mentoring scheme for junior researchers in our group

To receive further information or to enquire about collaborative research, please do not hesitate to contact the research group convenor, Dr C.F. Zhang (e-mail: zhangcf@hku.hk). For a selection of recent research published by the Biomedical and Tissue Engineering Research Group, see our "Research Synopses".


Members of Biomedical and Tissue Engineering Research Group

Group Convenor
Dr C.F. Zhang

Deputy Convenor
Dr D.W. Green

Primary Members
Dr M.F. Burrow
Professor G.S.P. Cheung
Professor L.K. Cheung
Dr W.S.W.Choi
Dr T.K. Goto
Dr D.W. Green
Dr T.C. Hsung
Dr M.Y.Y.Leung
Dr J. Lo
Dr Y.K. Lung
Dr L. Ma
Dr J.P. Matinlinna
Professor N. Samman
Dr A.T.H. Tang
Dr J.K.H. Tsoi
Dr R.W.K. Wong
Dr Y.Q. Yang
Dr C.K.Y. Yiu
Dr C.F. Zhang
Dr L.W. Zheng
Professor R.A. Zwahlen

Affliated member
Dr C.H. Chu
Professor L.J. Jin
Dr G.H.M. Lee
Dr W.K. Luk
Dr R.M. Watt