Academic Staff

Heng, Alexis Boon Chin

Dr Heng, Alexis Boon Chin

BSc (UK), MCE (Singapore), PhD (UK)

Title: Post-doctoral Fellow in Biomedical and Tissue Engineering
Discipline area: Endodontology
E-mail:
Tel: 2859 0527

Areas of Research Expertise

  1. Biomaterials
  2. Stem cells
  3. Regenerative medicine
  4. Tissue engineering

Faculty Research Group

Selected Latest Publications

Journal:

  1. XU J, Zhu S, Heng BCA, Dissanayaka WL & Zhang C. TGF-β1-induced differentiation of SHED into functional smooth muscle cells. Stem Cell Research & Therapy 2017;8(10). doi:10.1186/s13287-016-0459-0
  2. GONG T, Heng BCA, XU J, Zhu S, YUAN C, Lo ECM & Chen Q. Decellularized extracellular matrix of human umbilical vein endothelial cells promotes endothelial differentiation of stem cells from exfoliated deciduous teeth. Journal of Biomedical Materials Research Part A 2017;105:1083-1093. doi:10.1002/jbm.a.36003
  3. Heng BCA, GONG T, Wang S, Lim LW, Wu W & Zhang C. Decellularized Matrix Derived from Neural Differentiation of Embryonic Stem Cells Enhances the Neurogenic Potential of Dental Follicle Stem Cells. Journal of Endodontics 2017;43(3):409-416. doi:10.1016/j.joen.2016.10.033
  4. ZOU T, Dissanayaka WL, Jiang S, Wang S, Heng BCA, Huang X & Zhang C. Semaphorin 4D Enhances Angiogenic Potential and Suppresses Osteo-/Odontogenic Differentiation of Human Dental Pulp Stem Cells. Journal of Endodontics 2017;43:297-305. doi:10.1016/j.joen.2016.10.019
  5. Heng BCA, Zhang C, Deng X, Xiao Y, Pisciotta A, Kidwai F & Mitsladis TA. Biomedical Applications of Dental and Oral-Derived Stem Cells. Stem Cells International 2017;2017:1-2. doi:10.1155/2017/2931054
  6. Zhu S, Wang PL, Liao C, Yang Y, YUAN C, WANG S, Dissanayaka WL, Heng BCA & Zhang C. Transgenic expression of ephrinB2 in periodontal ligament stem cells (PDLSCs) modulates osteogenic differentiation via signaling crosstalk between ephrinB2 and EphB4 in PDLSCs and between PDLSCs and pre-osteoblasts within co-culture. Journal of Periodontal Research 2016;. doi:10.1111/jre.12424
  7. YUAN C, Wang P, Zhu S, ZOU T, Wang S, XU J, Heng BCA, Diogenes A & Zhang C. EphrinB2 Stabilizes Vascularlike Structures Generated by Endothelial Cells and Stem Cells from Apical Papilla.. Journal of Endodontics 2016;42:1362-1370. doi:10.1016/j.joen.2016.05.012
  8. Deng Z, Wang S, Heng BCA, YUAN C & Zhang C. Enterococcus faecalis promotes osteoclast differentiation within an osteoblast/osteoclast co-culture system. Biotechnology Letters 2016;38:1443-1448. doi:10.1007/s10529-016-2142-z
  9. Zhang X, Wu Y, Pan Z, Sun H, Wang J, Yu D, Zhu S, Dai J, Chen Y, Tian N, Heng BCA, Coen ND, Xu H & Ouyang H. The effects of lactate and acid on articular chondrocytes function: Implications for polymeric cartilage scaffold design. Acta Biomaterialia 2016;. doi:10.1016/j.actbio.2016.06.029
  10. Heng BCA, Ye X, LIU Y, Dissanayaka WL, Cheung GSP & Zhang C. Effects of Recombinant Overexpression of Bcl2 on the Proliferation, Apoptosis, and Osteogenic/Odontogenic Differentiation Potential of Dental Pulp Stem Cells. Journal of Endodontics 2016;42:575-583. doi:10.1016/j.joen.2016.01.013

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