Academic Staff

Jin, Lijian

Professor Jin, Lijian

DDS (Zhejiang Med), MMedSc (Karolinska Inst), PhD (Beijing Med), OdontDr (Karolinska Inst), Hon FDSRCSEd

Title: Clinical Professor in Periodontology
Discipline area: Periodontology
E-mail:
Tel: 2859 0302
Research profiles: HKU Scholars Hub Scopus Biomedexperts Researcher ID ORCID

Areas of Research Expertise

  1. Molecular mechanisms of periodontal pathogenesis
  2. Genetic markers and biomarkers for periodontal diseases
  3. Periodontal medicine
  4. Traditional Chinese medicine for periodontal treatment
  5. Clinical trials of periodontal care strategies
  6. Defensins in periodontal health and disease

Faculty Research Group

Selected Latest Publications

Journal:

  1. AB MALIK NB, ZHANG J, Lam OLT, Jin L & McGrath CPJ. Effectiveness of computer-aided learning in oral health among patients and caregivers: a systematic review. Journal of the American Medical Informatics Association 2017;24(1):209-217. doi:10.1093/jamia/ocw045
  2. JIANG S, Gao X, Jin L & Lo ECM. Salivary Microbiome Diversity in Caries-Free and Caries-Affected Children. International Journal of Molecular Sciences 2016;17:1978. doi:10.3390/ijms17121978
  3. Jin L, Lamster IB, Greenspan JS, Pitts NB, Scully C & Warnakulasuriya S. Global burden of oral diseases: emerging concepts, management and interplay with systemic health. Oral Diseases 2016;22:609-619. doi:10.1111/odi.12428
  4. HERATH MUDIYANSELAGE TDKH, Darveau RP, Seneviratne CJ, Wang C-Y, Wang Y & Jin L. Heterogeneous Porphyromonas gingivalis LPS modulates immuno-inflammatory response, antioxidant defense and cytoskeletal dynamics in human gingival fibroblasts. Scientific Reports 2016;6:29829. doi:10.1038/srep29829
  5. PANDUWAWALA KANKANAMALAGE CPPP, Zhan X, Dissanayaka WL, Samaranayake LP, Jin L & Zhang C. In vivo periodontal tissue regeneration by periodontal ligament stem cells and endothelial cells in three-dimensional cell sheet constructs. Journal of Periodontal Research 2016;. doi:10.1111/jre.12405
  6. REN C, McGrath CPJ, Jin L, Zhang C & Yang Y. Effect of diode low-level lasers on fibroblasts derived from human periodontal tissue: a systematic review of in vitro studies.. Lasers Med Sci 2016;. doi:10.1007/s10103-016-2026-4
  7. ACHARYA A, Koh ML, Kheur S, Watt RM, Jin L & Mattheos N. Salivary IL-1β and red complex bacteria as predictors of the inflammatory status in sub-peri-implant niches of subjects with peri-implant mucositis. Clinical Oral Implants Research 2016;27:662-667. doi:10.1111/clr.12713
  8. LI X, Wong CH, Ng TW, Zhang C, Leung KCF & Jin L. The spherical nanoparticle-encapsulated chlorhexidine enhances anti-biofilm efficiency through an effective releasing mode and close microbial interactions. International Journal of Nanomedicine 2016;:2471-2480. doi:10.2147/IJN.S105681
  9. Leung KCF, Seneviratne CJ, LI X, Leung PC, Lau CBS, Wong CH, Pang KY, Wong CW, Wat E & Jin L. Synergistic Antibacterial Effects of Nanoparticles Encapsulated with Scutellaria baicalensis and Pure Chlorhexidine on Oral Bacterial Biofilms. Nanomaterials 2016;6:61. doi:10.3390/nano6040061
  10. Cheng T, Li H, Xia W, Jin L & Sun H. Exploration into the nickel ‘microcosmos’ in prokaryotes. Coordination Chemistry Reviews 2016;311:24-37. doi:10.1016/j.ccr.2015.12.007

Books and Chapters

  1. Jin L. Periodontal screening and management: The foundation of general dental practice. In Periodontics: Beyond the pocket.2010,pp.58-65.
  2. Jin LJ. Periodontal infections, systemic inflammation and cardiovascular disease: current evident and perspectives. In In: A perspective of periodontal systemic relationships for the Asian Pacific region, ed. Bartold PM, Ishikawa I, Zhang J;.2008,pp.p.114-121.
  3. Berezow AB, Jin LJ & Darveau RP. The molecular basis of host defense mechanisms in oral disease. In In: Molecular Oral Microbiology. ed. Anthony H. Rogers;.2008,pp.p.237-255.
  4. Jin LJ. Periodontal medicine. In Clinical Periodontology.2006,pp.221-229.
  5. Jin LJ. Trauma from occlusion and occlusal therapy. In Clinical Periodontology.2006,pp.263-273.
  6. Jin LJ. Periodontal maintenance therapy. In Clinical Periodontology.2006,pp.362-368.
  7. Jin LJ. Research advances in periodontal etiopathology. In Research advances and clinical practice in periodontics: Bridging the gap.2006,pp.26-38.
  8. Jin LJ. Editor. In Year Book of Chinese Stomatology.2005,.
  9. Corbet EF & Jin LJ. Periodontal risk assessment and prognosis: Current status & future development - A Perspective From Hong Kong. In: Current trends in periodontal diagnosis, disease recongition and management. In Proceedings of the 5th Asian Pacific Society of Periodontology.2004,pp.67-72.
  10. Jin LJ. Editor. In Year Book of Chinese Stomatology.2004,.

Research Grants

Principal Investigator :

  1. 2014-: Crosstalk of human gingival/oral epithelial cells and monocytes with P. gingivalis/P. gingivalis DNA: Epigenetic regulation and molecular signaling [General Research Fund (GRF)] (HKD779,429)
  2. 2012-: Nano-encapsulated Chinese herbal extracts as novel immunomodulators and enhancers of innate host defense in human gingiva [General Research Fund (GRF)] (HKD1,244,865)
  3. 2012-: Mechanism of Antifungal Resistance in Candida Persisters: Roadmap to Unravel Biofilm Resistance? [Health and Medical Research Fund - Full Grant] (HKD965,360)
  4. 2012-: Novel antifungal small molecule for multi-drug resistant Candida: anti-biofilm activity, in vivo efficacy and cellular targets [Health and Medical Research Fund - Full Grant] (HKD935,360)
  5. 2012-: Identification of antifungal molecules from novel probiotic Lactobacillus bacteria for controlling Candida infection [Health and Medical Research Fund - Mini Grant] (HKD80,000)
  6. 2012-: Antifungal resistance and virulence attributes of Candida bloodstream isolates derived from Hong Kong [Health and Medical Research Fund - Mini Grant] (HKD80,000)
  7. 2011-: Effects of chronic periodontitis on endothelial progenitor cells: Molecular mechanisms and clinical implications [General Research Fund (GRF)] (HKD790,000)
  8. 2010-: Research Output Prize (Faculty of Dentistry) [Research Output Prize (in Faculty)] (HKD120,000)
  9. 2009-2011: Modulation of innate immune responses in human gingiva by P. gingivalis lipopolysaccharide with lipid A heterogeneity  Novel molecular mechanisms and clinical implications [General Research Fund (GRF)] (HKD755,760)
  10. 2009-2012: A clinical investigation on the association of periodontal disease with endothelial biomarkers and dysfunction [Small Project Funding] (HKD72,000)

Co-Investigator :

  1. 2014-: A randomized controlled trial of a laser-aided orthodontic treatment for patients with periodontitis [Health and Medical Research Fund - Full Grant] (HKD865,444) (with YANG Yan-Qi et al)
  2. 2014-: Does inflammation affect periodontal cell communication through Eph-ephrin under mechanical loading? [General Research Fund (GRF)] (HKD606,223) (with YANG Yan-Qi et al)
  3. 2013-: Engineering human dental pulp tissues using prevascularized microtissue spheroids constructed by dental pulp stem cells and gene-modified endothelial cells [General Research Fund (GRF)] (HKD1,128,000) (with ZHANG Chengfei et al)
  4. 2013-: Lipoteichoic acid (LTA) of pathogenic Enterococcus faecalis modulates the functional characteristics of osteoblasts and osteoclasts [Health and Medical Research Fund - Full Grant] (HKD765,000) (with ZHANG Chengfei et al)
  5. 2012-2013: Bacterial and inflammatory attributes for voice disorders in adult females [Small Project Funding] (HKD36,763) (with et al)
  6. 2012-2012: Periodontal pathogens inhibit endothelial healing: novel evidence of inflammation in atherosclerosis [Small Project Funding] (HKD36,800) (with LI, Xiao et al)
  7. 2011-2012: Synergistic effects of endothelial progenitor cells and apical papilla stem cells on dental pulp regeneration [General Research Fund (GRF)] (HKD493,000) (with ZHANG Chengfei et al)
  8. 2010-2011: Cross-talk of host oral epithelial cells with commensal and pathogenic bacteria [Seed Funding Programme for Basic Research] (HKD120,000) (with C. Jayampath Seneviratne et al)
  9. 2009-2011: Dentin-pulp complex and periodontal tissues regeneration in root canal perforation by the stem cells from the apical papilla and periodontal ligament. [Seed Funding Programme for Basic Research] (HKD120,000) (with ZHANG Chengfei et al)
  10. 2009-2010: Phosphoproteomics of Candida hyphal formation [Small Project Funding] (HKD80,000) (with C. Jayampath Seneviratne et al)

Honours and Awards

  1. 2016 Journal of Endodontics Awards, the best articles published in JOE during the 2015 calendar year . 2016. Dissanayaka WL, ZHU L, Hargreaves KM, Jin L & Zhang C.
  2. Best poster award Salivary Research Group, International Association for Dental Research. 2016. JIANG S, Gao X, Jin L & Lo ECM.
  3. 2016 IADR/AADR William J. Gies Award for Biomaterials and Bioengineering Research IADR/AADR. 2016. Dissanayaka WL, ZHU L, Hargreaves KM, Jin L & Zhang C.
  4. 2012 International Association for Dental Research (IADR) - South East Asia Division /Unilever Hatton Divisional Award (Senior category), Hong Kong (Primary Supervisor for Ms. H.J. Li, a PhD student) IADR - Southeast Asian Division. 2012. LI H, Seneviratne CJ, Wang CY & Jin L.
  5. 2012 International Association for Dental Research (IADR)/Colgate Research in Prevention Travel Award, Iguaçu, Brazil (Co- supervisor for Mr. W.L. Dissanayaka, a PhD student) IADR. 2012. Dissanayaka WL, Zhang C, Hargreaves KM & Jin L.
  6. 2012 International Association for Dental Research (IADR)/Colgate Research in Prevention Travel Award, Iguaçu, Brazil (Primary Supervisor for Dr. P.H. Ding, a PhD student) IADR. 2012. Ding P, Darveau RP, Wang CY & Jin L.
  7. Faculty Knowledge Exchange Award 2012 University of Hong Kong. 2012. Lo ECM, Seneviratne CJ, Gao X, Jin L, Samaranayake LP & Bridges SM.
  8. Research Output Prize The University of Hong Kong. 2012. Seneviratne CJ, Wang Y, Jin L & Samaranayake LP.
  9. 2011 International Association for Dental Research (IADR) - South East Asia Division /Unilever Hatton Divisional Award (Senior category), Singapore (Primary Supervisor for Ms. H.M.T.D.K. Herath, a PhD student) IADR - South East Asia Division. 2011. Herath MTDKH, Wang Y, Seneviratne CJ, Darveau RP, Wang CY & Jin L.
  10. 2011 International Association for Dental Research (IADR)/Colgate Research in Prevention Travel Award (Primary Supervisor for Ms. H.M.T.D.K. Herath, a PhD student) . 2011. Jin L.

Editorships

  1. Editorial Board Member (Journal of Clinical Periodontology) 2011
  2. Editorial Board Member (2010.1- 2012.12) (Journal of Dental Research) 2010
  3. Associate Editor (2009 - present) (Journal of Investigative & Clinical Dentistry) 2009
  4. Editorial Board Member (International Dental Journal) 2008
  5. Editorial Board Member (Journal of Periodontal Research) 2008
  6. Deputy Editor (Hong Kong Dental Journal) 2007
  7. Editorial Board Member (overseas) (Chinese Journal of Dental Research) 2007
  8. Associate Editor (Prosthodontic Research & Practice (Japan)) 2007
  9. Editorial Board Member (Asian Journal of Oral & Maxillofacial Surgery) 2007
  10. Member of Editorial Advisory Board (Journal of Periodontology) 2007

Additional Academic Appointments

  1. Visiting Professor. Sun Yat-Sen University Guanghua College of Stomatology, Guangzhou, China, May 15, 2008 2008
  2. Honorary Professor. Wenzhou Medical School, Institute of Stomatology, Wenzhou, China, November 2007 2007
  3. Honorary Professor, Wenzhou Medical College, Institute of Stomatology, Wenzhou, China. Wenzhou Medical College, Institute of Stomatology, Wenzhou, China, November 2007 2007
  4. Honorary Professor. Zhejiang University School of Medicine, Hangzhou, China, December 2005. 2005
  5. Honorary Professor, Zhejiang University School of Medicine, Hangzhou, China, December 2005.. Zhejiang University School of Medicine, Hangzhou, China 2005
  6. Guest Associate Professor. Peking University School of Stomatology 2002
  7. Guest Associate Professor, Stomatological College. Hubei Medical University, Wuhan, China 2000

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