Academic Staff

Zheng, Liwu

Dr Zheng, Liwu

DDS, MD (Wuhan), PhD (HK)

Title: Clinical Associate Professor in Oral Medicine
Discipline area: Oral and Maxillofacial Surgery
E-mail:
Tel: 2859 0558
Research profiles: HKU Scholars Hub Scopus

Areas of Research Expertise

  1. Oral mucosal disease and precancerous lesions
  2. Healing of compromised tissue (such as by heavy smoking or radiotherapy)
  3. Regenerative dentistry

Faculty Research Group

Selected Latest Publications

Journal:

  1. Cai WX, Zheng L, Huang HZ & Zwahlen RA. Evidence of phenotypic stability after transduction of fluorescent proteins in two human tongue cancer cell lines. Arch Oral Biol 2017;79:48-54.
  2. Li KL, Wang YF, Qin JR, Wang F, Yang YT, Zheng L, Li MH, Kong J, Zhang W & Yang HY. Rapamycin enhances the anti-angiogenesis and anti-proliferation ability of YM155 in oral squamous cell carcinoma. Tumour Biol 2017;39:1010428317706213.
  3. Bornstein MM & Zheng L. Wie steht es mit der malignen Transformation beim oralen Lichen planus?. Quintessenz 2017;68:805–813.
  4. Cai WX, Zheng L, Ma L, Huang HZ, Yu RQ & Zwahlen RA. Tumorigenicity And Validity Of Fluorescence Labelled Mesenchymal And Epithelial Human Oral Cancer Cell Lines In Nude Mice. Biomed Res Int 2016;2016:4897986.
  5. LIU XL, RAO NJ, HUO L, HU X, Lu WW & Zheng L. The influence of locally applied granulocyte-colony stimulating factor on osteoporotic bone.. Clin Oral Implants Res 2016;28:586-593. doi:10.1111/clr.12839
  6. LIU XL, HU X, CAI WX, Lu WW & Zheng L. Effect of Granulocyte-Colony Stimulating Factor on Endothelial Cells and Osteoblasts. Biomed Res Int 2016;. doi:10.1155/2016/8485721
  7. LI C, Lu WJW, Seneviratne CJ, Leung WK, Zwahlen RA & Zheng L. Role of periodontal disease in bisphosphonate-related osteonecrosis of the jaws in ovariectomized rats. Clinical Oral Implants Research 2016;27 (1):1-6.
  8. LIU X, LI C, Lu WW, CAI W & Zheng L. Role of periodontal disease in bisphosphonate-related osteonecrosis in ovariectomized rats. Clin Oral Implants Res 2016;27(1):1-6. doi:232381
  9. LI CL, SENEVIRATNE CJ, HUO L, Lu WW & Zheng L. Impact of Actinomyces naeslundii on bisphosphonate-related osteonecrosis of the jaws in ovariectomized rats with periodontitis. J Craniomaxillofac Surg 2015;43:1662-1669. doi:10.1016/j.jcms.2015.07.001
  10. Li JY, Zheng L, Ma L, Kwong DLW, Cheung LK & Pow EHN. Effect of fluoride-modified titanium surface on early adhesion of irradiated osteoblasts. BioMed Research International 2015;:1-9. doi:10.1155/2015/219752

Books and Chapters

  1. Hua H & Zheng L. . In Oral and Maxillofacial Diseases.2012,.
  2. Zheng L & Cheung LK. Distraction osteogenesis. In Oral and Maxillofacial Surgery.In press2010,.
  3. Cheung LK, Chua HDP, Hariri F, Lo J, Ow A & Zheng L. Distraction Osteogenesis (Chapter 48). In Oral and Maxillofacial Surgery, edited by Lars Andersson, Karl-Erik Kahnberg and M. Anthony Pogrel.2010,pp.1027 - 1059.
  4. Zheng L & Cheung LK. Stem cells in dentistry. In Stem Cell and Regenerative Medicine by Herman S. Cheung (Ed.).Chapter 102010,pp.176-186.
  5. Zheng L. Management of craniofacial trauma. In Treatment of trauma in craniofacial surgery.2002,pp.96-118.
  6. Zheng L. Reconstruction principle for craniofacial trauma. In Treatment of trauma in craniofacial surgery.2002,pp.364-89.
  7. Zheng L & Xu YY. . In Essential Microbiology for Dentistry.In press.

Research Grants

Principal Investigator :

  1. 2014-: Role of low dose bisphosphonate in compromised host with preriodontal diseases: risk or benefit? [Seed Funding Programme for Basic Research] (HKD35,800)
  2. 2013-: Role of Denosumab in inducing jawbone osteonecrosis on a rat model [Seed Funding Programme for Basic Research] (HKD67,300)
  3. 2013-: Impact of oral bacteria on unmasking bisphosphonate-related osteonecrosis of the jaws [General Research Fund (GRF)] (HKD639,000)
  4. 2012-: Role of oral bacteria in unmasking bisphosphonate-related osteonecrosis of the jaws [Seed Funding Programme for Basic Research] (HKD51,000)
  5. 2011-2013: Effect of granulocyte colony-stimulating factor on healing of aged osteoporotic bone [Seed Funding Programme for Basic Research] (HKD58,000)
  6. 2009-2012: Roles of costimulatory molecules in pathogenesis and malignant transformation of oral mucosal lesions [Seed Funding Programme for Basic Research] (HKD120,000)
  7. 2007-2009: Ideal rate for bone traction in continuous distraction osteogenesis [Small Project Funding] (HKD61,500)

Co-Investigator :

  1. 2013-: Epithelial mesenchymal transition (EMT) and its effect in oral squamous cell carcinoma progression [Seed Funding Programme for Basic Research] (HKD84,100) (with ZWAHLEN Roger Arthur et al)
  2. 2012-: Is Rb pathway useful in predicting malignant transformation of oral leukoplakia? [Seed Funding Programme for Basic Research] (HKD120,000) (with CHOI Winnie Wing Shan et al)
  3. 2010-2011: The thermogelling chitosan/collagen composite hydrogel blended with BMP-2 loaded nanoparticles for bone tissue engineering. [Small Project Funding] (HKD47,576) (with Peng Lin et al)
  4. 2010-: Biological characterization of different sources of dental stem cells [Seed Funding Programme for Basic Research] (HKD61,000) (with CHEUNG Lim K et al)
  5. 2010-2012: Release of vessel development in heterotopically cultured bone [General Research Fund (GRF)] (HKD626,140) (with ZWAHLEN Roger Arthur et al)
  6. 2009-2011: Effect of nicotinic acetylcholine receptors on mesenchymal stem cells [Small Project Funding] (HKD66,667) (with MA Li et al)
  7. 2008-2010: Can continuous distraction osteogenesis shorten the treatment time? [General Research Fund (GRF)] (HKD797,943) (with CHEUNG Lim K et al)
  8. 2008-2010: Gene therapy for tissue-engineered craniofacial bone reconstruction [Seed Funding Programme for Basic Research] (HKD78,000) (with CHEUNG Lim K et al)
  9. 2008-2010: Release of vessel development in heterotopically cultured bone [Seed Funding Programme for Basic Research] (HKD119,600) (with ZWAHLEN Roger Arthur et al)
  10. 2007-2008: Modulation of distraction osteogenesis in the irradiated mandible [Seed Funding Programme for Basic Research] (HKD100,000) (with CHEUNG Lim K et al)

Honours and Awards

  1. The best poster award at the 3rd Hiroshima Conference Hiroshima University. 2009. Ke J, Cheung LK & Zheng L.
  2. Best Original Article Award - Effect of recombinant human bone morphogenetic protein-2 on mandibular distraction osteogenesis Hong Kong Dental Journal. 2009. Cheung LK & Zheng L.
  3. Outstanding Oral Presentation Award at the Second International Conference on Evidence-based Advanced Dentistry The University of Hong Kong. 2007. Zheng L.
  4. Best Oral Presentation (Senior Category) at the 20th Annual Scientific Meeting Faculty of Dentistry, The University of Hong Kong. 2006. Zheng L.

Editorships

  1. Member of editorial board (American Journal of Oral Medicine) 2014
  2. Journal editor (International Journal of Dentistry) 2014
  3. Member of editorial board (Archives of Oral and Dental Research) 2014
  4. Journal editor (Biomedicine Research International) 2013
  5. Annals of Plastic Surgery () 2011
  6. Invited Reviewer (Journal of Cranio-Maxillofacial Surgery) 2009
  7. Invited Reviewer (Tissue Engineering) 2009
  8. Invited Reviewer (China Journal of Oral and Maxillofacial Surgery) 2009
  9. (Member of Advisory Board) (International Journal of Academic Research) 2009
  10. Invited Reviewer (International Journal of Oral Maxillofacial Surgery) 2009

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