Academic Staff

Dissanayaka, Waruna Lakmal

Dr Dissanayaka, Waruna Lakmal

BDS (Sri Lanka) PhD (HK)

Title: Research Assistant Professor in Biomedical and Tissue Engineering
Discipline area: Applied Oral Sciences
Tel: 2859 0527
Research profiles: HKU Scholars Hub Scopus

Areas of Research Expertise

  1. Tissue engineering
  2. Tooth-derived stem cells
  3. Dental pulp regeneration

Faculty Research Group

Selected Latest Publications


  1. Dissanayaka WL & Zhang C. The Role of Vasculature Engineering in Dental Pulp Regeneration. Journal of Endodontics 2017;43:S102-S106. doi:10.1016/j.joen.2017.09.003
  2. XU J, Zhu S, Heng BCA, Dissanayaka WL & Zhang C. TGF-β1-induced differentiation of SHED into functional smooth muscle cells. Stem Cell Research & Therapy 2017;8(10). doi:10.1186/s13287-016-0459-0
  3. Panduwawala Kankanamalage CPP, Zhan X, Dissanayaka WL, Samaranayake LP, Jin L & Zhang C. In vivo periodontal tissue regeneration by periodontal ligament stem cells and endothelial cells in three-dimensional cell sheet constructs. Journal of Periodontal Research 2017;52:408-418. doi:10.1111/jre.12405
  4. ZOU T, Dissanayaka WL, Jiang S, Wang S, Heng BCA, Huang X & Zhang C. Semaphorin 4D Enhances Angiogenic Potential and Suppresses Osteo-/Odontogenic Differentiation of Human Dental Pulp Stem Cells. Journal of Endodontics 2017;43:297-305. doi:10.1016/j.joen.2016.10.019
  5. Zhu S, Wang PL, Liao C, Yang Y, YUAN C, WANG S, Dissanayaka WL, Heng BCA & Zhang C. Transgenic expression of ephrinB2 in periodontal ligament stem cells (PDLSCs) modulates osteogenic differentiation via signaling crosstalk between ephrinB2 and EphB4 in PDLSCs and between PDLSCs and pre-osteoblasts within co-culture. Journal of Periodontal Research 2016;. doi:10.1111/jre.12424
  6. Heng BCA, Ye X, LIU Y, Dissanayaka WL, Cheung GSP & Zhang C. Effects of Recombinant Overexpression of Bcl2 on the Proliferation, Apoptosis, and Osteogenic/Odontogenic Differentiation Potential of Dental Pulp Stem Cells. Journal of Endodontics 2016;42:575-583. doi:10.1016/j.joen.2016.01.013
  7. Dissanayaka WL, ZHU L, Hargreaves KM, Jin L & Zhang C. In vitro analysis of scaffold-free prevascularized microtissue spheroids containing human dental pulp cells and endothelial cells. Journal of Endodontics 2015;41:663-670. doi:10.1016/j.joen.2014.12.017
  8. YUAN C, Wang P, ZHU L, Dissanayaka WL, Green DW, Tong EH, Jin L & Zhang C. Coculture of stem cells from apical papilla and human umbilical vein endothelial cell under hypoxia increases the formation of three-dimensional vessel-like structures in vitro. Tissue Engineering Part A 2015;21(5-6):1163-1172. doi:10.1089/ten.tea.2014.0058
  9. ZHU L, Dissanayaka WL, Green DW & Zhang C. Stimulation of EphB2/ephrin-B1 signalling by tumour necrosis factor alpha in human dental pulp stem cells. Cell Proliferation 2015;48:231-238. doi:10.1111/cpr.12172
  10. Dissanayaka WL, Hargreaves KM, Jin L, Samaranayake LP & Zhang C. The interplay of dental pulp stem cells and endothelial cells in an injectable peptide hydrogel on angiogenesis and pulp regeneration in vivo. Tissue Engineering Part A 2015;21(3-4):550-563. doi:10.1089/ten.tea.2014.0154

Honours and Awards

  1. 2016 IADR William J Gies Award for Biomaterials and Bioengineering Research International Association of Dental Research. 2016. Dissanayaka WL.
  2. 2016 IADR/AADR William J. Gies Award for Biomaterials and Bioengineering Research IADR/AADR. 2016. Dissanayaka WL, ZHU L, Hargreaves KM, Jin L & Zhang C.
  3. 2016 Journal of Endodontics Awards, the best articles published in JOE during the 2015 calendar year . 2016. Dissanayaka WL, ZHU L, Hargreaves KM, Jin L & Zhang C.
  4. Journal of Endodontics Award for the Best Paper in Basic Science: Biology 2016 Journal of Endodontics & American Association of Endodontists. 2016. Dissanayaka WL.
  5. Research Output Award - Faculty of Dentistry 2016 . 2015. Dissanayaka WL, Zhang C & Jin L.
  6. 2012 International Association for Dental Research (IADR)/Colgate Research in Prevention Travel Award, Iguaçu, Brazil (Co- supervisor for Mr. W.L. Dissanayaka, a PhD student) IADR. 2012. Dissanayaka WL, Zhang C, Hargreaves KM & Jin L.

  To Top