Professor Guang HONG

Biography

Professor Chu is a Professor and Associate Dean of the Faculty of Dentistry, The University of Hong Kong (HKU) with a demonstrated history of working in the clinical dentistry, administration and leadership, clinical and basic research, and higher education. He is the President, the Society of Preventive Dentistry of Hong Kong (2021-23), the President, the Asia Academy of Preventive Dentistry (2021-23), a Member, the FDI Public Health Committee (2021-24), and the Immediate Past President, the South East Asians Association for Dental Education (2021-23). Dr Chu practiced dentistry for 15 years and was the dental surgeon in charge of the HKU Health Service before he became an academics. He is a fellow of the Hong Kong College of Dental Surgeons, a fellow of the Hong Kong Academy of Medicine and a registered specialist in Family Dentistry in Hong Kong. Through overseas examinations, Dr Chu became a fellow of the Royal Australasians College of Dental Surgeons (RACDS) in Sydney, a dental fellow of the Royal College of Surgeons in Edinburgh (RCSEd) UK, and a diplomate of the American Board of General Dentistry in Chicago. He lectured widely in international conferences. Through his exceptional achievements in clinical care, teaching and research, Dr Chu was elected as a fellow of the International College of Dentists, a fellow of the Faculty of Dental Trainers RCSEd and a fellow of the Academy of Dental Materials, respectively. He published extensively with a Scopus h index of 40. He is an editor of several SCI journals.

Professor Chun Hung CHU

Biography

Professor Chu is a Professor and Associate Dean of the Faculty of Dentistry, The University of Hong Kong (HKU) with a demonstrated history of working in the clinical dentistry, administration and leadership, clinical and basic research, and higher education. He is the President, the Society of Preventive Dentistry of Hong Kong (2021-23), the President, the Asia Academy of Preventive Dentistry (2021-23), a Member, the FDI Public Health Committee (2021-24), and the Immediate Past President, the South East Asians Association for Dental Education (2021-23). Dr Chu practiced dentistry for 15 years and was the dental surgeon in charge of the HKU Health Service before he became an academics. He is a fellow of the Hong Kong College of Dental Surgeons, a fellow of the Hong Kong Academy of Medicine and a registered specialist in Family Dentistry in Hong Kong. Through overseas examinations, Dr Chu became a fellow of the Royal Australasians College of Dental Surgeons (RACDS) in Sydney, a dental fellow of the Royal College of Surgeons in Edinburgh (RCSEd) UK, and a diplomate of the American Board of General Dentistry in Chicago. He lectured widely in international conferences. Through his exceptional achievements in clinical care, teaching and research, Dr Chu was elected as a fellow of the International College of Dentists, a fellow of the Faculty of Dental Trainers RCSEd and a fellow of the Academy of Dental Materials, respectively. He published extensively with a Scopus h index of 40. He is an editor of several SCI journals.

Professor Jiang CHEN

Biography

Dr Jiang CHEN, Dean and Professor of School and Hospital of Stomatology Fujian Medical University. He obtained his M.D. and Ph.D. degrees in Oral and Maxillofacial Surgery from West China School of Stomatology, Sichuan University, China. He worked as a visiting scholar in Harvard School of Dental Medicine, Tufts-New England Medical Center, Massachusetts (USA) from 2000 to 2001. His research interests includes digital occluso-rehabilitation, maxillofacial tumor research, oral implant, clinical research of oral aesthetics. He has published nearly 100 papers and accomplished nearly 20 research projects, including 2 projects supported by the National Natural Science Foundation of China. He edited, translated and co-edited 11 academic monographs. Due to the outstanding achievements, he awarded as “National Excellent Scientist” and “Recipient of special subsidies acknowledged by the State Council”. He is also a fellow of International Team for Implantology (ITI), an expert reviewer of NSFC and CSC, editor in chief of JOMI Chinese edition, reviewer of clinical oral implant research, special reviewer of Chinese Journal of Stomatology, and deputy editor in chief of Journal of Stomatology. Being a well recognized expert in his field, Prof. Chen is appointed as Director of academic board, school and hospital of stomatology Fujian Medical University, Executive Director of Chinese Stomatological Association, Director of Oral Implantology Committee and Oral Aesthetics Committee of Chinese Stomatological. He was also elected as a Fellow of International College of Dentists (FICD).

Professor Chengfei ZHANG

Topic

Crosstalk of ECs and DPSCs on Vascular Maturation

Abstract

Dental pulp stem cells (DPSCs) display multiple functions during DPSC-induced vasculature formation. At the early stage, DPSCs secrete pro-angiogenic factors, such as VEGF, to promote early vascular network formation and, at the late stage, act as pericyte-like cells for vascular stabilization by transforming their MSC phenotype to smooth muscle cell-like phenotype via TGF-β overexpression. When ECs and DPSCs were directly co-cultured, pericyte markers in DPSCs were elevated along with increased TGF-β1 secretion, while indirectly co-cultured cannot. HUVECs and TGF-β1 could induce DPSC differentiation into functional SMCs, and Ang1/Tie2/VE-cadherin and VEGF/VEGFR2 signaling pathways contributed to vascular stabilization induced by DPSCs. There are associations between the actions of TGF-β/Smad on DPSC differentiation toward pericyte phenotypes and the actions of Ang-1/Tie2 and VEGF/VEGFR2 signaling on DPSC-induced vascular maturation. These results broaden our understanding of the crosstalk between DPSCs and ECs, which may open a new avenue for applying DPSCs in vascular tissue engineering for dental pulp regeneration.

Biography

Professor Chengfei Zhang is a clinical professor in Endodontics, Associate Dean for Research and Innovation, Faculty of Dentistry, The University of Hong Kong (HKU). He serves as an editorial board member for International Endodontic Journal, International Dental Journal, and Bioengineering. He obtained his DDS and Ph.D. degrees from Peking University. He joined the Faculty of Dentistry HKU in 2009. His innovative research activities are internationally recognized, and he was awarded the IADR William J Gies Award for Biomaterials and Bioengineering Research, the Journal of Endodontics award for best paper, and the IADR distinguished scientist. His research in endodontic etiopathogenesis and pulp regeneration has been funded by Hong Kong RGC and Chinese mainland funding. He has lectured on many occasions nationally and internationally, particularly in IADR/AADR and IADR-SEA meetings, and published over 200 journal papers/book chapters.

Professor Masahiro SAITO

Topic

Crosstalk of ECs and DPSCs on Vascular Maturation

Abstract

Bone tissue engineering has been developed by combination of mesenchymal stem cells (MSCs) and ceramic based scaffold; however, these complexes could not be achieved regeneration of large bone defect such as horizontal bone defect in jawbone. To overcome this problem, novel bone regeneration technology must be developed using cells possessing high bone forming ability and scaffold that can provide space for vertical bone formation. To approach this problem, we have developed alveolar bone derived immature osteoblast like cells (HAOB) which has high bone regeneration ability for regeneration of large bone defect and graft material combining polylactic acid fiber that organize three-dimensional structure and increasing the strength of the scaffold material (3DPLA) suitable for bone formation. HAOB-3DPLLA cannot regenerate bone by xenogeneic transplantation in micromini pig alveolar bone defect model, however, autogenic transplantation of mice calvaria derived immature osteoblast like cells (MCOB) which isolated by identical protocol of HAOB mixed with 3DPLA were able to regenerate large jawbone defect model in mice compared with those of 3DPLA alone. Nano indentation analysis indicated regenerated bone had similar mechanical strength to intact bone and generate osseointegration in which a direct structural and functional connection between living bone and the surface of implant. Thus, complex of immature osteoblast like cells such as MCOB and 3DPLA may represent as a novel bone tissue engineering technology that enables vertical bone formation with suitable mechanical property that is required for the treatment of large bone defect.

Biography

Dr Saito is a professor department of Restorative dentistry in Tohoku University, Graduate School of Dentistry and Vice-Director of Dental Division, Tohoku University Hospital, with specialist of the advance clinical dental treatment including bone regeneration study. He had been working in Kanagawa Dental College as an instructor, Department of operative dentistry (1988~1994). Through overseas examinations, Dr Saito became a visiting Fellow, School of Medicine, Department of Pathology, University of Washington, Seattle, WA for investigating periodontal regeneration mechanism (1994-1996). He has been working for extracellular matrix that induce periodontal ligament wound healing after back to Kanagawa dental college (1996-2002). He became lecturer in Department of Molecular and Cellular Biochemistry, Osaka University Graduate School of Dentistry for investigating bone tissue engineering (2006-2009), and move to Faculty of Biological Science, Tokyo University of Science as an associate professor to investigate tooth regeneration (2009-2013). Through his exceptional achievements in clinical care, teaching and research, Dr Chu was elected as a professor at Division of Ecological Dentistry, Department of Restorative Dentistry, Tohoku University, Graduate School of Dentistry. He is now working in clinical application of regeneration therapy using immature osteoblast or adipose derived stem cell, anti-inflammatory therapy in endodontics and diagnostic technology using saliva.

Professor Xiaojing HUANG

Topic

How Does Apical Periodontitis Affect the Health of Remote Organs?

Abstract

Over the past two decades, our understanding of the relationship between periodontal disease and cardiovascular disease, diabetes, preterm birth, respiratory disease, and other systemic disorders has greatly improved. Similarly, there is growing evidence that apical periodontitis (AP) can also induce a systemic immune response that is not limited to localized lesions and has the potential to trigger a systemic inflammatory response. Our series uses experimental animal models to explore how AP can elevate systemic inflammatory factor levels and cause pathological changes in remote organs (e.g. liver and aortic arch).

Biography

Professor Huang Xiaojing is the Associate Dean and Professor (Endodontics and Operative Dentistry) at the School and Hospital of Stomatology, Fujian Medical University. She began her career in endodontics and operative dentistry after receiving her BSc, MSc, and Ph.D. degrees from the West China School of Stomatology, Sichuan University. She worked as a visiting scholar at King’s College London (UK) from 2003 to 2004. Her research interests are in endodontics and cariology. She has published more than 90 papers and completed more than 20 research projects, including three projects funded by the National Natural Science Foundation of China, and won the third prize in Science and Technology Progress in Fujian Province. Due to her outstanding achievements, she was recognized as a "High-Level Talent in Fujian Province" and was awarded the titles of "Outstanding Contribution to Young and Middle-aged Experts" and "Returned Talent with Study Abroad" by the Fujian Provincial Health Commission. A recognized expert in the field, Professor Huang is responsible for the national first-class course in Endodontics and is one of the editorial members of the national planning textbook of Endodontics for General Higher Education. She is also the Deputy Director of the Committee on Geriatric Dentistry and Deputy Director of the Committee on Laser Dentistry of the Chinese Society of Stomatology. In addition, she is also the Vice President of the Fujian Provincial Dental Association and the Chairman of the Laser Dentistry Committee of the Fujian Provincial Dental Association.

Professor Richard Yuxiong SU

Topic

Computer-assisted Surgery and 3D Printing in Oral and Maxillofacial Surgery: A Paradigm Shift

Abstract

In recent years, computer-assisted surgery and 3D printing have led to a paradigm shift in the clinical practice of Oral and Maxillofacial Surgery. In this presentation, we will summarize our clinical translational studies in the use of 3D printing in maxillofacial tumor resection, microsurgical reconstruction, maxillofacial bone fracture, orthognathic surgery, and temporomandibular join surgery. We have developed a comprehensive workflow and facilitated the use of surgical cutting guides and patient-specific surgical plates in various surgical procedures. The results of our series studies have showed that computer-assisted surgery and 3D printing increased surgical efficiency, improved surgical accuracy, facilitated complicated procedures, enhanced predictability and repeatability of surgery, which lead to the consistently favorable surgical outcomes. The disadvantages and limitations will also be discussed. With the combination of new technologies such as augmented reality and artificial intelligence, computer-assisted surgery and medical 3D printing will further shape the future of surgery.

Biography

Professor Richard Yuxiong Su currently works as Clinical Professor and Chief of Division of Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong. He is also an Honorary Professor at the Department of Otorhinolaryngology, Chinese University of Hong Kong. Prof Su is an Education Committee member of the International Association of Oral and Maxillofacial Surgeons. He serves as international faculty and Asia Pacific Board member of the AO Craniomaxillofacial Foundation. He also works as an Associate Editor of Frontiers in Oncology (Head and Neck Cancer Section) and Deputy Editor of Craniomaxillofacial Trauma & Reconstruction. His main research areas include clinical and translational research in oral and maxillofacial oncology, microsurgical reconstruction, and salivary gland diseases, with special focus on computer-assisted surgery and 3D printing in head and neck reconstruction. He has published more than 120 manuscripts in peer-reviewed international journals. Prof Su is the inventor of seven patents, including two US and EU patents and five China patents. He has been awarded eight peer-reviewed external research grants as the principal investigator. Prof Su has been invited to give lectures in numerous international and regional conferences and courses. He is ranked by Clarivate Analytics in the top 1% researcher worldwide by citations in 2021 and 2022.

Professor Tsuyoshi SUGIURA

Topic

Non-Invasive Early Detection and Real-Time Monitoring of Oral Cancer

Abstract

The term "precision medicine" mainly refers to the precise analysis of genetic abnormalities in tumors and the targeting of treatment, but, even if genetic abnormalities are discovered, there is often no corresponding therapeutic drug. Only few cases reach treatment for this reason. Furthermore, it is known that oral cancer does not have characteristic "driver genes" related to carcinogenesis and malignant traits. Therefore, precision medicine needs to focus on precise and early diagnosis in oral cancer. However, the reality is that it is often discovered as a super-advanced case. In another aspect, cancer is diagnosed clinically based on "morphological changes" by visual inspection and palpation, and then pathologically by "morphological changes" of biopsy specimens. Accuracy of diagnosis largely depends on the subjective judgment and experience of the doctor. In addition, once the tumor is resected, diagnosis of recurrence and metastasis largely depends on imaging diagnosis, making real-time monitoring of the tumor difficult. Against this background, we have been developing a "precision diagnosis and monitoring" method that allows anyone to monitor the diagnosis of oral cancer easily, noninvasively, and continuously, which shows diversity. On this talk, I will introduce an ultra-sensitive diagnosis method for oral cancer with DNA methylation as an index using an oral rinse sample, and oral cancer diagnosis and metastasis monitoring with serum miRNA as an index.

Biography

Dr Sugiura is Professor of Division of Oral and Maxillofacial Oncology and Surgical Sciences at Tohoku University School of Dentistry and has been involved in oral and maxillofacial surgery, especially oral oncology and surgery, management and instruction, clinical and basic research, and higher education. In clinical practice, he specializes in oral cancer resection and reconstruction, and in research, he specializes in the development of cancer early detection technology using gene mutation as an indicator and its application in cancer treatment. He is currently a director/advising physician of the Japanese Society of Stomatology, a councilor/advising physician of the Japanese Society of Oral and Maxillofacial Surgeons, and a councilor of the Japanese Society of Oral Medicine. Dr. Sugiura obtained a doctorate in dentistry from Osaka University School of Dentistry and conducted research on invasion and metastasis of oral cancer while performing clinical work as a medical staff at Osaka University Hospital. After working as a Research Fellow at the CRC Institute for Cancer Studies at the University of Birmingham in the UK, he worked as an Assistant Professor in the Department of Oral Surgery at Kyushu University and Associate Professor in the Department of Maxillofacial Oncology at Kyushu University. In 2022, he became a professor in the Department of Oral and Maxillofacial Oncology and Surgical Sciences, Tohoku University, where he is today. He also takes the role of editor in some of SCI journals.

Professor Kensuke YAMAUCHI

Topic

Contemporary Orthognathic Surgery and Future Prospects

Abstract

Treatment for jaw deformity is characterized by the collaboration of surgery and orthodontics in the treatment of abnormalities of the teeth, alveolar region, and jawbone. The role of the oral surgeon is to perform orthognathic surgery to improve the position of the skeletal bone, and while there have been no major changes or modifications in surgical techniques since the 2000s, there have been significant changes in surgical equipment and imaging-related developments. In terms of surgical instruments, the application of ultrasonic bone cutting devices has improved safety through minimally invasive surgery, and in terms of imaging, there has been the dramatically changes of a treatment system that incorporates three-dimensional imaging, from surgical simulation using CT imaging to guided surgery using CAD/CAM splints or patient specific implants. In addition to the development of treatment for jaw deformities as described above, we have begun to develop new techniques such as exoscopic surgery, in which surgery is performed under indirect vision with a view toward robotic surgery, and navigation for three-dimensional positioning of the maxilla. One of the changes that occurred during the spread of the COVID-19 was the development and spread of remote environments using high-speed information and communication technology, which led to the expansion of online medical treatment. In the treatment of jaw deformities, online remote collaboration is gradually being introduced, expanding the possibilities of remote collaborative care. In this lecture, I would like to report an overview of the past and present situation, introduce the initiatives with an awareness of future medicine, and discuss the future of jaw deformity treatment.

Biography

Dr Yamauchi is a Professor of division of Oral and Maxillofacial Reconstructive Surgery, Graduate School of Dentistry and vice director of Dental Implant Center of Tohoku University Hospital. He is the president of Strasbourg Osteosynthesis Research Group in Japan (SORG Japan), a fellow of International Team for Implantology (ITI) and an executive board member of Japanese Society of Jaw Deformity (JSJD). Dr Yamauchi practiced Oral and Maxillofacial Surgery for 22 years in Kyushu Dental College and Tohoku University and a specialist and supervisory doctor certified by Japanese Society of Oral and Maxillofacial Surgery (JAOMS). His specialties are orthognathic surgery, preprosthetic surgery related to dental implant treatment, reconstructive surgery, computer assisted surgery, endo- / exoscopic- surgery, and temporomandibular joint surgery. The research fields are bone generation, 3D morphological analysis of face and innovative navigation system for oral and maxillofacial surgery. He lectured widely in international conference and published text books.

Professor Chun Hung CHU

Biography

Professor Chu is a Professor and Associate Dean of the Faculty of Dentistry, The University of Hong Kong (HKU) with a demonstrated history of working in the clinical dentistry, administration and leadership, clinical and basic research, and higher education. He is the President, the Society of Preventive Dentistry of Hong Kong (2021-23), the President, the Asia Academy of Preventive Dentistry (2021-23), a Member, the FDI Public Health Committee (2021-24), and the Immediate Past President, the South East Asians Association for Dental Education (2021-23). Dr Chu practiced dentistry for 15 years and was the dental surgeon in charge of the HKU Health Service before he became an academics. He is a fellow of the Hong Kong College of Dental Surgeons, a fellow of the Hong Kong Academy of Medicine and a registered specialist in Family Dentistry in Hong Kong. Through overseas examinations, Dr Chu became a fellow of the Royal Australasians College of Dental Surgeons (RACDS) in Sydney, a dental fellow of the Royal College of Surgeons in Edinburgh (RCSEd) UK, and a diplomate of the American Board of General Dentistry in Chicago. He lectured widely in international conferences. Through his exceptional achievements in clinical care, teaching and research, Dr Chu was elected as a fellow of the International College of Dentists, a fellow of the Faculty of Dental Trainers RCSEd and a fellow of the Academy of Dental Materials, respectively. He published extensively with a Scopus h index of 40. He is an editor of several SCI journals.

Professor Chengfei ZHANG

Biography

Professor Chengfei Zhang is a clinical professor in Endodontics, Associate Dean for Research and Innovation, Faculty of Dentistry, The University of Hong Kong (HKU). He serves as an editorial board member for International Endodontic Journal, International Dental Journal, and Bioengineering. He obtained his DDS and Ph.D. degrees from Peking University. He joined the Faculty of Dentistry HKU in 2009. His innovative research activities are internationally recognized, and he was awarded the IADR William J Gies Award for Biomaterials and Bioengineering Research, the Journal of Endodontics award for best paper, and the IADR distinguished scientist. His research in endodontic etiopathogenesis and pulp regeneration has been funded by Hong Kong RGC and Chinese mainland funding. He has lectured on many occasions nationally and internationally, particularly in IADR/AADR and IADR-SEA meetings, and published over 200 journal papers/book chapters.

Professor Richard Yuxiong SU

Biography

Professor Richard Yuxiong Su currently works as Clinical Professor and Chief of Division of Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong. He is also an Honorary Professor at the Department of Otorhinolaryngology, Chinese University of Hong Kong. Prof Su is an Education Committee member of the International Association of Oral and Maxillofacial Surgeons. He serves as international faculty and Asia Pacific Board member of the AO Craniomaxillofacial Foundation. He also works as an Associate Editor of Frontiers in Oncology (Head and Neck Cancer Section) and Deputy Editor of Craniomaxillofacial Trauma & Reconstruction. His main research areas include clinical and translational research in oral and maxillofacial oncology, microsurgical reconstruction, and salivary gland diseases, with special focus on computer-assisted surgery and 3D printing in head and neck reconstruction. He has published more than 120 manuscripts in peer-reviewed international journals. Prof Su is the inventor of seven patents, including two US and EU patents and five China patents. He has been awarded eight peer-reviewed external research grants as the principal investigator. Prof Su has been invited to give lectures in numerous international and regional conferences and courses. He is ranked by Clarivate Analytics in the top 1% researcher worldwide by citations in 2021 and 2022.

Professor Cynthia YIU

Biography

Professor Cynthia Yiu is a Clinical Professor in Paediatric Dentistry, Associate Dean in Clinical Affairs and Postgraduate Programme Director in Paediatric Dentistry, Faculty of Dentistry, the University of Hong Kong (HKU). She received the Bachelor of Dental Surgery degree from King’s College, University of London and completed her Master of Dental Surgery (MDS) degree and Doctor of Philosophy degree from HKU. Prof Yiu is a Fellow of the Hong Kong Academy of Medicine (Dental Surgery), the College of Dental Surgeons of Hong Kong (Paediatric Dentistry) and the International College of Dentists. Prof Yiu received the “Faculty Outstanding Teacher Award” and “Outstanding Team-Teaching Award” from HKU in 2011 and 2013, respectively. She has supervised over 10 PhD students and 30 MDS students. She is currently serving on the Editorial Board of Journal of Dentistry, International Dental Journal and BMC Oral Health. Her research areas are adhesive dentistry, cariology and paediatric oral health. Prof Yiu’s research team have won several awards at the annual meetings of International Association for Dental Research and International Association of Paediatric Dentistry. She has published over 250 journal papers and book chapters, which aimed at prevention of dental caries and improvement of durability of adhesive restorations.

Professor Masahiro SAITO

Biography

Dr Saito is a professor department of Restorative dentistry in Tohoku University, Graduate School of Dentistry and Vice-Director of Dental Division, Tohoku University Hospital, with specialist of the advance clinical dental treatment including bone regeneration study. He had been working in Kanagawa Dental College as an instructor, Department of operative dentistry (1988~1994). Through overseas examinations, Dr Saito became a visiting Fellow, School of Medicine, Department of Pathology, University of Washington, Seattle, WA for investigating periodontal regeneration mechanism (1994-1996). He has been working for extracellular matrix that induce periodontal ligament wound healing after back to Kanagawa dental college (1996-2002). He became lecturer in Department of Molecular and Cellular Biochemistry, Osaka University Graduate School of Dentistry for investigating bone tissue engineering (2006-2009), and move to Faculty of Biological Science, Tokyo University of Science as an associate professor to investigate tooth regeneration (2009-2013). Through his exceptional achievements in clinical care, teaching and research, Dr Chu was elected as a professor at Division of Ecological Dentistry, Department of Restorative Dentistry, Tohoku University, Graduate School of Dentistry. He is now working in clinical application of regeneration therapy using immature osteoblast or adipose derived stem cell, anti-inflammatory therapy in endodontics and diagnostic technology using saliva.

Professor Tsuyoshi SUGIURA

Biography

Dr Sugiura is Professor of Division of Oral and Maxillofacial Oncology and Surgical Sciences at Tohoku University School of Dentistry and has been involved in oral and maxillofacial surgery, especially oral oncology and surgery, management and instruction, clinical and basic research, and higher education. In clinical practice, he specializes in oral cancer resection and reconstruction, and in research, he specializes in the development of cancer early detection technology using gene mutation as an indicator and its application in cancer treatment. He is currently a director/advising physician of the Japanese Society of Stomatology, a councilor/advising physician of the Japanese Society of Oral and Maxillofacial Surgeons, and a councilor of the Japanese Society of Oral Medicine. Dr. Sugiura obtained a doctorate in dentistry from Osaka University School of Dentistry and conducted research on invasion and metastasis of oral cancer while performing clinical work as a medical staff at Osaka University Hospital. After working as a Research Fellow at the CRC Institute for Cancer Studies at the University of Birmingham in the UK, he worked as an Assistant Professor in the Department of Oral Surgery at Kyushu University and Associate Professor in the Department of Maxillofacial Oncology at Kyushu University. In 2022, he became a professor in the Department of Oral and Maxillofacial Oncology and Surgical Sciences, Tohoku University, where he is today. He also takes the role of editor in some of SCI journals.

Professor Kensuke YAMAUCHI

Biography

Dr Yamauchi is a Professor of division of Oral and Maxillofacial Reconstructive Surgery, Graduate School of Dentistry and vice director of Dental Implant Center of Tohoku University Hospital. He is the president of Strasbourg Osteosynthesis Research Group in Japan (SORG Japan), a fellow of International Team for Implantology (ITI) and an executive board member of Japanese Society of Jaw Deformity (JSJD). Dr Yamauchi practiced Oral and Maxillofacial Surgery for 22 years in Kyushu Dental College and Tohoku University and a specialist and supervisory doctor certified by Japanese Society of Oral and Maxillofacial Surgery (JAOMS). His specialties are orthognathic surgery, preprosthetic surgery related to dental implant treatment, reconstructive surgery, computer assisted surgery, endo- / exoscopic- surgery, and temporomandibular joint surgery. The research fields are bone generation, 3D morphological analysis of face and innovative navigation system for oral and maxillofacial surgery. He lectured widely in international conference and published text books.

Professor Dali ZHENG

Biography

Dr Dali ZHENG professor of Fujian Key laboratory of Oral Diseases, School and Hospital of Stomatology, Fujian Medical University. He received BSc degree in Biochemistry from Fudan University, graduated with MSc in Immunology from Fujian Medical University, and obtained PhD in Biochemistry and Molecular Biology from Shanghai Jiaotong University. He was a postdoctoral research fellow at University of Missouri (USA) and Washington University in St Louis (USA) from 2009 to 2013, and research associate at Moffitt Cancer Center and University of South Florida (USA) from September of 2013 to January of 2018. He won the title of “Distinguished Professor of Minjiang Scholarship” in 2018 and is serving as academic editor for Journal of Oncology, reviewer for several international journals such as Ebiomedicine, Cancer Letters, International Journal of Oncology, Journal of Cellular Biochemistry, Oncology Reports and so on. He published more than 50 research papers in international journals including Nature Nanotechnology, Oncogene, JCI, PNAS, and BMC Cancer and won First-class prize of Natural Science Award of Ministry of Education (4th authorship) in 2016 and Second-class prize of Scientific Innovation Award of Fujian Province (2nd authorship) in 2017. His research is mostly focused on the molecular biology of oral cancer and oral microenvironment.

Professor Linyu XU

Biography

Dr Linyu XU is professor of School and Hospital of Stomatology, Fujian Medical University. He received BDS and MDS from School of Stomatology, Fujian Medical University. His research interests include biomechanics of orthodontic tooth movement, temporomandibular joint disease & occlusal disorders and clinical research of orthodontics. He was awarded the honor of "National Excellent Orthodontic Star" of the Orthodontic Committee in Chinese Stomatological Association in 2020-2021, and “Outstanding Teacher, Outstanding Clinical Instructor and Educator " acknowledged by Fujian Medical University. He is the editor of Journal of Prevention and Treatment for Stomatological Diseases, as well as the instructor of China Tweed Center and a member of International RW Orthodontic Association and a guest editor of Chinese Journal of Orthodontics. He has published more than 30 papers and accomplished over 10 research projects. Clinically, Linyu Xu has efficiently completed thousands of craniofacial anomalies cases, helped many people obtain a full smile and enabling them to live with confidence. Many of his completed cases have won numerous awards in national case competitions, which have also been selected for inclusion in the Chinese Clinical Case Achievement Database or published in domestic and international journals such as the Chinese Journal of Stomatology and BMC oral health. He also participated in the edition of Orthodontics, which is the textbook of Chinese technical secondary schools, organized by "Thirteenth Five-Year Plan" of the National Health and Family Planning Commission.

Professor Dong WU

Biography

Dr Dong Wu is professor of School and Hospital of Stomatology,Fujian Medical University. He is also the director of Oral and Craniofacial Implant Research Center and the deputy director of the Implantology Dept. He received BDS and MDS from School of Stomatology, Fujian Medical University. He worked as a visiting scholar in Institute of Health and Biomedical Innovation, Queensland University of Technology (AUS) from 2003 to 2006. His research interests include bone regeneration, sinus floor elevation with concentrated growth factor application, accuracy implant using dynamic naigation system and implant robots, and other related clinical research in implantology. He is the editor of Clinical Oral Implant Research (Chinese version) and Vice editor-in-chief of International Journal of Oral and Maxillofacial Implants(Chinese Version). He has published more than 50 papers and accomplished over 15 research projects. He has also won the third prize of 2012 and 2017 Fujian medical science and technology award, and science and technology progress award of Fujian Province in 2013. Dr. Dong Wu has efficiently completed thousands of complex implant surgery, helped many people obtain a full smile and enabling them to live with confidence. Due to his outstanding contribution in dental implant field, he was appointed to be the judge for several scholarly panels and competitions, such as the judges of the BITC Dental Implant Competition and the judges of East China Debating Competition of Dental Implant Prosthesis.

Dr George PELEKOS

Topic

Furcation involvement in Periodontology. What we learned so far and the future treatment concepts

Abstract

The treatment of teeth with furcations affected by periodontal disease is one of the most difficult problems for the general dentist and periodontist. When the periodontal disease affects the furcation, tooth loss chance increases considerably. Exposed root surface, anatomical peculiarities, and irregularities of the furcation surface all favour the growth of bacteria accompanied by limited access to treatment for the operator and limitations on the performance of oral hygiene for the patient. No ideal procedure for treating such lesions exists, so this presentation will aim to elaborate on different treatment concepts from the past till the present when it comes to teeth affected by furcation involvement. This presentation aims to help clinicians understand and consider their experience when treating advanced periodontal diseases and seek consultation with a specialist when in doubt regarding the prognosis and treatment of those teeth.

Biography

MUDr. George Pelekos, after the completion of his studies in the Medical faculty of Masaryk University in the Czech Republic, was awarded the degree of Doctor of Medicine with an MSc in the area of oral pathology. In 2006 (MClinDent), he began his training in a full-time program and completed his specialization degree in Periodontology (2009) at the prestigious Eastman Dental Institute in London (UCL). After his graduation, he continued to work at Eastman, initially as a research assistant & later as a senior clinical lecturer. George has been lecturing worldwide and is a member of several scientific organizations (ITI, IADR). He is also holding a membership with the Royal College of Surgeons (Glg), and he serves as a trainer for the College of Dental Surgeons in Hong Kong and a visiting professor at Kings College London. Early in 2014, he was appointed as a Clinical Assistant Professor in Periodontology at the Dental Faculty of Hong Kong University. Since then, he has published a good number (>60) of research papers in reputable international peer-reviewed journals and completed his Ph.D. at Tohoku University in Japan. He has also secured different research grants as the principal or Co/Investigator (14,5M HKD). In addition, he is currently a member of the editorial board of the Journal of Clinical Periodontology. Areas of research interest include clinical periodontology, peri-implantitis, wound healing, probiotics, periodontal medicine, and evidence-based analysis. Currently, he is the Director of the Periodontology postgraduate program at HKU, the only program outside Europe accredited by the European Federation of Periodontology (EFP).

Dr Chloe Meng JIANG

Topic

Community-based participatory research in dentistry: from bench-side, chair-side to community

Abstract

Traditionally, academia played a key role in conducting research by identifying research gaps, applying funding and implementing research projects. However, there are challenges about for whom, how, and what is defined as useful knowledge. Growing interest has been raised in a collaborative approach to “co-create” knowledge by engaging both researchers and communities. Community-based participatory research (CBPR) is a research approach that emphasize the importance of creating partnerships between researchers and people (knowledge users) in the community who are ultimately meant to benefit from the knowledge generated. CBPR values the unique strength and authority of the community and tries to de-centered the “expertise” of the researchers. Communities are encouraged to take every step of the research process including the development of research questions, decisions about methodology, involvement in data collection, interpretation and dissemination of findings. CBPR in dentistry is a promising research method to engage researchers as well as communities to co-create knowledge which will ultimately benefit the community.

Biography

Dr Chloe Meng Jiang is a clinical assistant professor at Faculty of Dentistry, The University of Hong Kong (HKU). Dr Jiang obtained her bachelor and master degrees in Stomatology from West China School of Stomatology, Sichuan University, China, and received her PhD and MSc (Community Dentistry) degrees from Faculty of Dentistry, HKU. Dr Jiang is a member of the Royal Australasian College of Dental Surgeons in specialist dental practice of dental public health, MRACDS(DPH). Her research focuses on population oral health and evidence-based dentistry. She was awarded the Pediatric Oral Health Research Young Investigator Award, IADR, 2020 and HKU Research Output Prize, 2021. Dr Jiang serves as a reviewer in several reputable dental journals such as Journal of Dentistry and International Journal of Dentistry, and she is also a guest editor of one special issue of Dentistry Journal. Besides, Dr Jiang has been actively involved in knowledge exchange activities and community services, and was awarded the Knowledge Exchange Award, 2021.

Dr Ollie Yiru YU

Topic

Digital Diagnostic Aids for Caries Detection

Abstract

The advance in digital diagnostic techniques has significantly facilitated the detection of dental caries in recent years. Digital diagnostic aids for caries detection can be classified according to the initial source of energy. Radiography, digital transillumination imaging, fluorescence imaging, laser-induced thermal imaging, multiphoton microscopy, optical coherence tomography, ultrasonic imaging and electric-based detections are now available as digital diagnostic aids for dental caries detection to supplement the conventional visual/tactile approaches. Digital radiography uses ionizing radiation, normally X-ray to produce images of dental structures. Digital transillumination imaging shows the optical feature of the carious lesion by transmitting near-infrared light through the teeth. Fluorescence imaging detects the changes in the fluorescence induced by laser or visible lights on the carious teeth. Laser-related imaging shows the feature change of the carious lesion induced by laser. Thermal imaging shows the thermal profile of the carious teeth. Multiphoton microscopy captures the signal of laser-excited photons from carious tooth structure. Optical coherence tomography used optical coherence light to reveal the optical scattering properties of the caries lesion. Ultrasonography detects the signal of ultrasound waves to assess the acoustic impedance of the carious teeth. Electric-based detection assesses the changes in the electric current or impedance of the teeth with caries. This lecture gives an overview of the available digital diagnostic aids for caries detection.

Biography

Dr Ollie Yu is a clinical assistant professor in Cariology under the discipline of Restorative Dental Sciences at the Faculty of Dentistry, The University of Hong Kong (HKU). She has been involved extensively in undergraduate and postgraduate teaching in HKU. She is currently the course coordinator of Cariology, the year director of BDS year 2 and the deputy chief examiner of BDS 2. She also serves as supervisor and examiner of postgraduate students in HKU. Dr Yu’s research direction and interest focus on Cariology, including caries microbiology, caries detection, minimal intervention dentistry, caries prevention, caries control and dental materials related to caries management. She has published around 40 articles in peer-reviewed journals and holds a patent in glass ionomer cement. She received several international awards on cariology research and dental education. Dr Yu is the editor of several indexed journals including Scientific Report, Dentistry Journal and Frontiers in Oral Health. She also serves as the journal reviewers for multiple peer-reviewed journals and abstract reviewer for several international conferences including the International Association of Dental Research and the Asian Academy of Preventive Dentistry. She is the council member of the Society of Preventive Dentistry of Hong Kong.

Dr Walter Yu Hang LAM

Topic

Use of Artificial Intelligence in Restorative Dentistry

Abstract

Artificial intelligence (AI) is a hot topic and has many applications in dentistry. This lecture will discuss some of the recent development and applications of AI in restorative dentistry with a focus on tooth replacement and gum disease detection.

Biography

Dr Walter Lam is a Clinical Assistant Professor in Prosthodontics, Faculty of Dentistry, The University of Hong Kong (HKU). As a clinician, he is a specialist in Prosthodontics and holds Fellowships from College of Dental Surgeons of Hong Kong, The Royal College of Surgeons of Edinburgh, The Royal College of Physicians and Surgeons of Glasgow, and The Royal Australasian College of Dental Surgeons. As a researcher, his research themes include Prosthodontics, Digital Dentistry, and Artificial Intelligence. He has published over 40 articles in peer-reviewed indexed journals and holds 4 patents. He received several prestigious research prizes in Prosthodontics, Digital Dentistry, and Artificial Intelligence. He and his team are the pioneers in the development of virtual dental patients, the application of artificial intelligence in dental disease detection, and tooth replacement. In the dental community, he served as the Editorial Board Member, Digital Dentistry Section, Journal of Dentistry (Q1 in dentistry), and the Secretary/Treasurer, Digital Dentistry Research Network, International Association of Dental Research (IADR). He represents Hong Kong in the Dental CAD/CAM Systems (TC 06/SC 9), International Standard Organization (ISO). He is an international dental advisor and examiner of the Royal College of Physicians and Surgeons of Glasgow.

Professor Guang HONG

Topic

Denture Care for the Elderly Person

Abstract

The number of people wearing dentures with dentures is increasing due to the progress of the super-aging society, and denture care, including cleaning dentures, managing dentures, and using denture adhesive becomes more critical for those elderly persons who wear dentures to improve oral-related QOL. Denture adhesives are roughly classified into denture adhesives and home reliner. Furthermore, denture adhesives are classified into three types: cream type, powder type, and sheet (tape) type. Denture cleansers also have several types such as Hypochlorite, Peroxide, Enzyme, and so on. Correct use of those materials and correctly introduction of those materials to patients is a critical issue. Otherwise, these materials can make some side effects. In this lecture, I will introduce the basics of denture adhesives and denture cleansers, how to use them, and patient guidance.

Biography

Professor Guang Hong is an Vice Dean of Graduate School of Dentistry, Tohoku University, and the Professor and Chair of Division for Globalization Initiative. He is also the Director of Office of International Affairs at the Liaison Center for Innovative Dentistry. Prof Hong was conferred his PhD from the Hiroshima University Graduate School of Dentistry in 2003. Prof Hong is an executive board member of the Japanese Society for Dental Materials and Devices and an associate editor of the Dental Materials Journal. He serves as the Director of The Japan Denture Care Society. He is also a committee member of the International Standardization Accelerated Project Japanese Ministry of Economy, Trade and Industry and an expert of the International Organization for Standardization (ISO) and the German Institute for Standardization (DIN). Prof Hong’s research interest includes elucidation of the rheology properties of dental materials, the development of functionality of new dental materials and dental education. His research is mainly concerned with international standard institution; improvement and development of oral care and denture care materials, metal-free dental implant materials and development of dental materials and dental education system according to the Industry-Academia-Government collaboration. He published more than 80 papers with high Impact Factor Scientific Journal. He received the Tohoku University Presidential Prize for Educational Excellence in 2019.

Dr Kenji TAKEUCHI

Topic

The Burden of Oral Health Problems in the Ageing Society

Abstract

In 2021, the World Health Assembly adopted a resolution on oral health. This resolution confirmed that the high prevalence of oral diseases is a global burden of disease and reiterated the importance of oral health. When discussing the importance of oral health, inequalities in oral health and its association with general health are also important topics. In this time, we will present the results of our study, which examined the impact of socioeconomic status on oral health and the association between oral health and non-communicable diseases, based on a large older adult population data set. In addition, in recent years, the association between oral and general health has sometimes been criticized as not causal due to the difficulty of conducting randomized controlled trials (RCTs). Thus, we would like to present some specific examples of our research on how causal inference methods can be applied to observational study data to elucidate the mechanisms of the link between oral and general health. We hope that the evidence for oral health in Japan, a super-aging society, will be helpful not only to our country but also to other countries where the population will be aging even more in the future.

Biography

Dr Takeuchi is a specially appointed professor at Tohoku University School of Dentistry with a demonstrated history of working in oral epidemiology, public health, and data health. He has previously worked in research and education as an Assistant Professor at the Department of Preventive and Public Health Dentistry, Kyushu University Faculty of Dental Science (2013-19) and as an Associate Professor at the Department of Preventive Medicine, Nagoya University Graduate School of Medicine (2019-21). Through various academic activities, he is certified as an advisor of the Japanese Society of Oral Hygiene (JSOH) and a senior epidemiologist of the Japan Epidemiological Association (JEA). In research, he has reported about 100 papers in international journals and has been the first author of 20 papers in the past 10 years. In particular, his representative paper (J Am Geriatric Soc 2017: 65; e95-e100), the first longitudinal examination of the association of oral health with the development of dementia by disease type, was featured in Wiley's Research Headline. He was awarded The J. Morita Post-doctoral Award for Junior Investigators for Geriatric Oral Research (First Prize) at the 94th International Association for Dental Research (IADR) Congress, demonstrating his research presence at international meetings.

Dr Juan Ramón VANEGAS SÁENZ

Topic

Clinical Outcomes of Indirect Adhesive Restorations

Abstract

Recent clinical research suggests that adhesive dentistry should be considered when restoring badly destroyed teeth. Partial restorations can be adhesively bonded to the remaining coronal structure, preserving more sound tooth structure. Indirect onlays may be a suitable alternative to full crowns as they preserve more sound tooth structure while providing cuspal coverage to protect weakened cusps. The use of alternative partial bonded restorations has allowed clinicians to adhesively restore teeth that would otherwise require extensive mechanical retention. Another challenge is restoring endodontically treated teeth without a ferrule, due to extensive structure loss, and the various options available for retention of the crown. The traditional cast post-and-core technique is associated with catastrophic failures, as posts have a higher elastic modulus than dentin, leading to concentrated stresses in the root and an increased incidence of root fractures. Enhanced adhesive procedures using adhesive luting systems in combination with prefabricated posts or glass fiber and direct core build-ups have also been shown to result in greater retention, less microleakage, and higher resistance against root fracture. In this case series presentation, we will describe various updated clinical procedures for the application of tooth-colored inlays and onlays. These procedures include immediate dentin sealing, cavity design optimization, core build-up, and cervical margin relocation. It is important to note that, although there is strong in vitro evidence to support the restoration quality of inlays and onlays placed using these procedures, no randomised prospective clinical studies have been published yet to confirm their success rates.

Biography

Dr. Vanegas is an Assistant Professor in the Division of Globalization Initiative at the Liaison Center for Innovative Dentistry in Tohoku University Graduate School of Dentistry, Japan. He has 14 years of experience in dentistry, with half of that time focused on esthetic, oral rehabilitation, and implant dentistry. He obtained his Doctor of Philosophy degree from Tohoku University Graduate School of Dentistry in 2017 in the Division of Advanced Prosthetic Dentistry. He also holds a Master of Science in Management and Quality Assurance in Higher Education from Universidad Jean Jacques Rousseau, Nicaragua since 2013. Dr. Vanegas graduated as a Doctor of Dental Surgery in 2009 from Universidad Nacional Autónoma de Nicaragua, León, Nicaragua. Currently, his research interests include dental biomaterials, bone regeneration, oral health, clinical dental research, and educational research. He has published various articles in peer-reviewed journals and conference proceedings. Dr. Vanegas is also an Invited Adjunct Professor for the Specialty Clinical Programs at Universidad Americana, Nicaragua, where he has received several awards and honours for being an outstanding undergraduate and graduate professor. His other relevant activities include giving lectures and participating in national and international conferences.

Professor Kai LUO

Topic

Effects of Nanosilicate-Incorporated Polycaprolactone on Periodontal Regenerations

Abstract

Periodontitis is a biofilm-induced chronic inflammatory disease, which destroys periodontal support tissue, and might cause tooth loss. The ultimate goal of periodontal treatments is the regeneration of all lost periodontal tissue. With great progress in regenerative medicine, biomimetic scaffold-mediated tissue regeneration proved to be a promising method to manipulate periodontal regeneration. Polycaprolactone (PCL), previously approved by the U.S. Food and Drug Administration (FDA), shows potential in periodontal regeneration. But it cannot directly regulate the regeneration process due to the limited pro-regenerative effects of pure PCL. Therefore, there is an urgent need to develop functional modifications to enrich the regenerative properties of PCL. Laponite (LAP) nanosilicate is a layered two-dimensional nanoscale, ultrathin nanomaterial with a unique structure and brilliant biocompatibility and bioactivity. Incorporation of LAP nanosilicate into PCL to obtain PCL/LAP composites could increase mechanical properties. Moreover, PCL/LAP orchestrated osteoblasts and bone marrow stromal cells to directly induce osteogenesis and indirectly regulate angiogenesis and osteoclastogenesis, ultimately accelerating bone regeneration. However, it is unclear whether PCL/LAP could promote periodontal regeneration. Periodontal ligament cells (PDLCs), derived from periodontal tissues, have been recognized as the main cells participating in periodontal regeneration, including the regeneration of periodontal ligament, alveolar bone and cementum. Based on our previous research, we investigated the effect of LAP on biocompatibility and bioactivity of PDLCs in vitro. Then, PCL/LAP nanofibrous membrane was fabricated by an electrospinning method and its effect on periodontal regeneration was evaluated in vivo. The results indicated PCL/LAP nanofibrous membrane could be a promising biomaterial for periodontal regeneration.

Biography

Professor Kai LUO, Associate Dean and Professor (Periodontology) of School and Hospital of Stomatology Fujian Medical University. He obtained BDS, MDS and PHD from School of Stomatology, Fujian Medical University and School of Stomatology, Wuhan University respectively. He worked as a visiting scholar in Institute of Health and Biomedical Innovation, Queensland University of Technology (AUS) from 2012 to 2013. His research interests are periodontal regeneration and clinical trails of periodontal care strategies. He has published more than 40 peer reviewed journal articles and accomplished over 10 research projects, including 2 projects supported by the National Natural Science Foundation of China. He translated and co-edited 4 academic monographs. He appointed as executive member of Periodontology Committee in Chinese Stomatology Association as well as Director of Periodontology Committee of Fujian Stomatology Association.

Dr Xindie HE

Topic

PGE2 transmition in osteocyte 3D network activated by titanium nanotopography under loading

Abstract

To investigate the role of the PGE2 in the osteocyte 3D network development under loading. Method: Mouse osteocyte-like cell lines, MLO-Y4, embedded in type I collagen gels were cultured on nano-roughened or clinically used micro-roughened titanium surfaces in a growth medium. Cell shapes and expressions of gap junction (CX43), dendrite (E11/gp38), and PGE2 (Ptgs2) markers were assessed using RT-PCR and/or immunofluorescent on day7. Concentration of PGE2 released in the supernatant were analyzed by ELISA on day 7. Cyclic loading were applied on the osteocytes containing collagen gel after 7- day- culture. Gene expression and western blotting analysis of PGE2 ( Ptgs2) and bone remodeling related marker (Opg, Rankl, Sost) and protein were evaluated afterwards. Meanwhile, immunofluorescent cytomorphometrical analyses of the cells in the collagen gel were performed after loading. Results: Osteocytes embedded in collagen gels on nano-roughened surfaces showed greater cellular interconnectivity with higher expressions of CX43, E11/gp38 and PGE2 than those on micro-roughened surfaces (Student’s t-test, P < 0.05). Meanwhile, the concentration of PGE2 were significantly higher in the supernatant of nano-roughend surfaced group than that in the micro-roughened surfaced group. Osteocyte 3D network activated by nano-roughened surface with loading induced bone formation with highly enhanced CX43 and PGE2 than those on the micro-roughened surfaces. Conclusion: Loading induced PGE2-meidate cellular communication in the osteocyte 3D network, resulting in bone formation.

Biography

Dr Xindie He is an assistant professor of School and Hospital of Stomatology, Fujian Medical University. She was conferred Bachelor of Medicine Stomatology from the Fujian Medical University and Doctor of Philosophy from Tohoku Univeristy. Her research is mainly about the osteocyte 3D network development on the titanium nanosurfaces. Dr. He has published an article named “Titanium nanotopography induces osteocyte lacunar-canalicular networks to strengthen osseointegration” in Acta Biomaterialia in 2022 as first author. This article has been selected as noteworthy by the Japan Society for Bone and Mineral Research. Dr. He achieved the Early Young Investigator Award in International Oral Health Symposium in 2022 and has been selected as finalist for the IADR from Japan division in 2021.

Dr Yuqing ZHANG

Topic

A simple double-U notched tensile test for orthodontic thermoplastic materials

Abstract

The aim of this study was to propose a simple tensile test that is applicable to orthodontic thermoplastic aligner materials. Three thicknesses (0.5, 0.625, and 0.75 mm) of polyethylene terephthalate glycol-modified (PETG) thermoplastic sheets were used and cut into unnotched rectangular (U) and double U-notched (N) specimens in three dimensional configurations: Type A: ~5.0mm (wide) × ~40.0mm (length); Type B: ~10.0mm × ~80.0mm; and Type C:~12.0mm ×~80.0mm. A total 144 specimens were loaded in tension by using a universal testing machine to determine force and displacement, while digital image correlation (DIC) and finite element analysis (FEA) were used to determine stress and strain. No significant difference in tensile strength was observed between UA and NA specimens. UB (43.6±1.3 MPa) and UC specimens (42.4±0.8 MPa) exhibited statistically significant higher tensile strengths (p <0.001) than NB (41.9±1.1 MPa) and NC (40.1±1.3 MPa) specimens, respectively. The discrepancy between notched and unnotched specimens in terms of maximum tensile force was positively correlated with the cross-sectional area (p=0.523, p <0.001). The prevalence of transverse necking was negatively correlated with the cross-sectional area (p =-0.684, p <0.001). The difference between the predetermined and the calculated elastic moduli of notched specimens was not significant. Greater variance was observed among the strain patterns in the unnotched specimens compared to the double-U notched specimens. The proposed double-U notched configuration is advisable for estimating tensile strength of thermoplastic materials, as it showed more reliable location of the fracture.

Biography

Dr Monica Yuqing ZHANG is an assistant professor of School and Hospital of Stomatology, Fujian Medical University. As a highly world-outlook-motivated person, she was deeply involved in the international academic communication. She attended the Sakura Science Program in Tohoku University, Japan in 2016. She was appointed as Honorary Research Associate in in Applied Oral Sciences, the University of Hong Kong from 2019 to 2022, to explore the new possibilities in dental materials of implantology and orthodontics. She was invited as a bilingual hostess of international meeting, such as the China-Japan-Korea Dental Science Symposium in 2016 and Oral Health Science and Education in Asia-Pacific Region in 2019. She sincerely hopes it would be an opportunity to share the passion and significance of her research in the TKU-HKU-FJMU International Symposium on Oral Health Science this year.

Dr Ruoyan GUO

Topic

Age and sex differences of young people’s oral functions

Abstract

The oral function is composed of seven domains categorized into three aspects: oral environment (oral hygiene and moisture), comprehensive ability (masticatory and swallowing function), and particular functions (occlusal force, tongue pressure, and tongue-lip motor function). It has been verified that the inferior oral function influences the general health condition. Especially for elderly people, oral condition will decrease with age. For confronting the degeneration of oral condition of elderly people, it is necessary to start paying more attention to the oral function of young people. If oral function of young people can be improved or maintained, it can better ensure that their oral function does not decline even in old age. Therefore the maintenance of preferable oral function will become increasingly important in the future. This trial investigated oral functions of young people from junior high school students to young adults. The methodology of this study is aligned as a cross-sectional clinical trial. As oral function requires maintenance throughout life, the current oral condition of different aspects needs to be understood across age groups. This lecture focuses on young people in Japan and illustrates the differences in oral function in these age groups.

Biography

Dr Ruoyan GUO graduated from Gerodontology and Oral Rehabilitation at Tokyo Medical and Dental University in Japan in 2022. Now She is an assistant professor of School and Hospital of Stomatology, Fujian Medical University. In her doctoral period, she participated in poster displays at several academic conferences held in Japan and Southeast Asia（IADR-Southeast Asia Division）. Dr. Guo published a thesis about the investigation of Oral function in young people. Dr. Guo’s research interests include denture adhesive, oral function, and oral hypofunction.

Dr Wei ZHAO

Topic

The effect of ACP augmentation technique for upper anterior teeth

Abstract

To compare the clinical efficacy evaluation of (autologous cortical plate, ACP) in digital prosthetic driven bone augmentation in the treatment of severe bone defects in upper anterior teeth, and to provide reference for the clinical application of ACP. Based on retrospective clinical research data, 28 patients with severe bone defects in the upper anterior teeth underwent bone augmentation surgery. Among them, 16 cases were treated with digital guided ACP grafting and bone grafting technology, and 12 cases were treated with conventional (Guided bone regeneration, GBR) technology. Compare the osteogenic effects of two methods in reconstructing three-dimensional bone defects in the aesthetic area, as well as the changes in bone resorption rate and three-dimensional alveolar bone increment after 1 year of implant loading. In terms of horizontal bone increment, GBR and ACP technology achieved greater bone increment within 6 months. After 1 year of loading with ACP, the horizontal bone absorption rate was lower, and the transplanted bone absorption rate was lower. After 1 year of loading, the cortical bone slice group received higher pink aesthetic PES scores. Both GBR and ACP technology can achieve good bone augmentation effects. Within 6 months, the bone resorption rate of GBR is relatively low. After 1 year of loading, the bone resorption rate of the ACP group is relatively low, and the transplanted bone volume is relatively stable.

Biography

Dr Zhao Wei, Senior assistant professor, has been engaged in clinical, scientific research, and teaching work related to Prosthodontics, Implantology, and Dental Aesthetics at the School and Hospital of Stomatology, Fujian Medical University for a long time. Currently, he serving as the Secretary of the Chinese Society of Esthetic Dentistry, a National Youth Member of the Chinese Society of Esthetic Dentistry, the first National Youth Lecturer of the Chinese Society of Esthetic Dentistry, and an Executive Member of the Society of Esthetic Dentistry of the Fujian Province Stomatological Association. And as a member of the International Team for Implantology (ITI), he has won multiple times in various domestic Dental Aesthetics and BITC dental implant case competitions for first place.