Academic Staff Project Benefit Mankind Being Supported
The Research Grants Council announced the results for the General Research Fund (GRF) exercises for 2022/2023. In the latest competitive exercise, five academic staff received the GRF. The list of successful GRF is as follows:
Clinical Professor in Cariology
Project TitleArresting dental caries with a novel silver complex fluoride
About the ProjectTo evaluate the effects of the SCF solution on 1) the architecture, viability, and kinetics of a multispecies cariogenic biofilm and 2) the mineral and organic content and colour change in carious teeth.
Clinical Associate Professor in Oral and Maxillofacial Surgery
Project TitleComprehensive validation of an Artificial Intelligence-enabled skull CT segmentation for computer-assisted head and neck reconstruction
About the ProjectTo validate the AI-enabled skull CT segmentation with dry human skulls anatomical ground truth; to validate the AI-enabled skull CT segmentation with a surgical database of computer-assisted head and neck reconstruction; and to verify the impact of the AI-enabled skull CT segmentation on the performance of computer-assisted head and neck reconstruction.
Clinical Associate Professor in Orthodontics
Project TitleIdentifying the role of Fto in modulating the transition of pro-inflammatory periodontium towards recovery in mechanical microenvironment
About the ProjectTo investigate the function of m6 A “eraser” Fto in the recovery of periodontium and the mechanism by which it regulates Socs1 m6 A methylation. This study may provide opportunities to develop novel therapeutic strategies for safe and effective orthodontic treatments for patients with periodontitis.
Clinical Professor in Paediatric Dentistry
Project TitleA novel calcium strontium silicate cement for dentin-pulp complex regeneration
About the ProjectResults of this project will provide new insights into the mechanisms underlying the odontogenic and immunomodulatory effects of CSR cement. Successful dentin-pulp regeneration via CSR cement will revolutionize endodontic therapy by reversing diseased tooth back to a healthy state, delivering a promising solution to endodontic diseases.
Clinical Professor in Endodontics
Project TitleEphrinB2 activation modulates the actions of TGF-β/Smad and Ang-1/Tie2 signaling in regulating DPSC-induced vascular formation
About the ProjectThis study will be the first to unravel the associations of EphrinB2/EphB4, TGF-β/Smad, and Ang-1/Tie2 signaling on the vascular maturation process by DPSCs. The new knowledge may bring much needed insight on dentin/pulp regeneration.