Profile
- Clinical Assistant Professor in Periodontology & Implant Dentistry
牙周病學及植齒學臨床助理教授
Periodontology & Implant Dentistry
+852 2859 0251
Clinical Artificial Intelligence
- Clinical Periodontology
- Artificial Intelligence in Diagnostic Medical Imaging
- Oral Health and Biological Aging
Article
- Li Yuan, Kung Julie Choi Ka, Shi Junyu, Wu Xinyu, Lam Steve Lut Ting, Deng Ke, Zhang Xiao, Lai Hongchang, Pelekos George, Jin Lijian, Tonetti Maurizio S. Diagnostic Accuracy of a Point‐Of‐Care aMMP‐8 Test for Discriminating Periodontal Health Status in Adults: Validation Trials and Updated Meta‐Analysis, Journal of Clinical Periodontology 2025;
- Du Mi, Deng Ke, Yin Jiawei, Wu Chenkai, Hu Shixian, Guo Linxu, Luo Zhixin, Tonetti Maurizio, Tjakkes Geerten‐Has E, Visser Anita, Ge Shaohua, Li An
. Association Between Chewing Capacity and Mortality Risk: The Role of Diet and Ageing, Journal of Clinical Periodontology 2025;
- Zhang Qinglian, Que Hanxin, Xu Shengming, Xu Leyan, Lin Jian, Deng Hui, Deng Ke, Wang Yi. The Association of Intake of Vitamin Mixtures With Periodontitis: A Machine Learning Approach on NHANES, Journal of Periodontal Research 2025;
- Yang Yumeng, Deng Ke, Jiang Shan, Guo Xiaolan, Zhong Yiming, Wu Buling, Wei Liu. Punicalagin ameliorates lipopolysaccharide-induced inflammatory response in dental pulp cells via inhibition of the NF-κB/Wnt5a-ROR2 pathway, Immunopharmacology and Immunotoxicology 2025;
- Xu Shengming, Zheng Cheng, Huang Jianmin, Lu Bin, Que Hanxin, Xu Leyan, Hou Yubo, He Linlin, Fan Xia, Deng Ke, Hu Rongdang, Deng Hui, Wang Yi. Porphyromonas gingivalis Induces Endothelial Dysfunction Through Sirt3-Dependent CypD Acetylation, Journal of Periodontal Research 2025;
- Herrera David, Tonetti Maurizio S., Chapple Iain, Kebschull Moritz, Papapanou Panos N., Sculean Anton, Abusleme Loreto, Aimetti Mario, Belibasakis Georgios, Blanco Juan, Bostanci Nagihan, Bouchard Philippe, Buduneli Nurcan, Calciolari Elena, Carra Maria Clotilde, Chackartchi Tali, Dannewitz Bettina, Danser Monique, Deng Coral, Derks Jan, Dietrich Thomas, Discepoli Nicola, Divaris Kimon, Dommisch Henrik, Donos Nikos, Dutzan Nicolás, Eickholz Peter, Eren Kuru Bahar, Faria Almeida Ricardo, Farina Roberto, Feher Balazs, Figuero Elena, Giannobile William, Gosset Marjolaine, Graziani Filippo, Gursoy Ulvi K., Hagenfeld Daniel, Jepsen Karin, Jepsen Sören, Kumar Purnima, Laine Marja L., Lambert France, Lang Niklaus P., Li Yuan, Loos Bruno, Madianos Phoebus, Matesanz Paula, Mealey Brian, Molina Ana, Montero Eduardo, Nibali Luigi, Preshaw Philip, Rakic Mia, Ramseier Christoph, Salvi Giovanni, Sánchez Nerea, Sanz-Sánchez Ignacio, Shapira Lior, Stavropoulos Andreas, Tamimi Faleh, Teughels Wim, Tomasi Cristiano, Trombelli Leonardo, Vassilopoulos Spyros, Verket Anders, West Nicola, Windisch Peter, Sanz Mariano. Consensus Report of the 20th European Workshop on Periodontology: Contemporary and Emerging Technologies in Periodontal Diagnosis, Journal of Clinical Periodontology 2025;
- Wang Ziyan, Guo Lvhua, Deng Ke, Yu Ting, Li Ping. Additively manufactured zirconia periodontal splint integrated prosthesis: A proof-of-concept, Journal of Dentistry 2025; 156
- Cao Yu, Pelekos George, Jin Lijian, Li An, Du Mi, Hu Shixian, Liu Zuyun, Deng Ke. Dissecting the causal association of periodontitis with biological aging and its underlying mechanisms: findings from Mendelian randomization and integrative genetic analysis, Journal of Periodontal & Implant Science 2025; 55
- Wei Xindi, Zhuang Longfei, Zhang Xiao, Deng Ke, Chen Ruiying, Liu Beilei, Lai Hongchang. Association of Masticatory Function With Mortality in Older Adults
, International Dental Journal 2025; 75(6)
- Li Yuan, Cui Zhiming, Mei Lanzhuju, Xie Yu, Marini Lorenzo, Pelekos George, Gu Wen, Yu Xiaoyu, Wu Xinyu, Wei Xindi, Tao Leran, Deng Ke, Pilloni Andrea, Shen Dinggang, Tonetti Maurizio S.. A novel AI-powered radiographic analysis surpasses specialists in stage II–IV periodontitis detection: a multicenter diagnostic study, npj Digital Medicine 2025; 8(1)
- Deng Ke, Song Yimeng, GBD 2021 Causes of Death Collaborators. Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021, The Lancet 2024;
- Wei Shimin, Lin Tingting, Sáenz‐Ravello Gustavo, Gao Hanqi, Zhang Yong, Tonetti Maurizio S, Deng Ke. Diagnostic accuracy of salivary active matrix metalloproteinase (aMMP)‐8 point‐of‐care test for detecting periodontitis in adults: A systematic review and meta‐analysis, Journal of Clinical Periodontology 2024;
- Ma Lei, Zhang Jingyang, Deng Ke, Xue Peng, Cui Zhiming, Fang Yu, Tan Minhui, Zhao Yue, Zhu Min, Ding Zhongxiang, Shen Dinggang. Construction of unbiased dental template and parametric dental model for precision digital dentistry, Biomedical Signal Processing and Control 2024; 95
- Naghavi M, Ong KL, Aali A, Ababneh HS, Abate YH, Abbafati C, Abbasgholizadeh R, Abbasian M, Abbasi-Kangevari M, Abbastabar H, Abd ElHafeez S, Abdelmasseh M, Abd-Elsalam S, Abdelwahab A, Abdollahi M, Abdollahifar MA, Abdoun M, Abdulah DM, Abdullahi A, Abebe M, Abebe SS, Abedi A, Abegaz KH, Abhilash ES, Abidi H, Abiodun O, Aboagye RG, Abolhassani H, Abolmaali M, Abouzid M, Aboye GB, Abreu LG, Abrha WA, Deng K, Guo C, Song Yimeng, and others. Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021, The Lancet 2024; 403(10440): 2100-2132
- Li Yuan, Wu Xinyu, Liu Min, Deng Ke, Tullini Annamaria, Zhang Xiao, Shi Junyu, Lai Hongchang, Tonetti Maurizio S.. Enhanced control of periodontitis by an artificial intelligence-enabled multimodal-sensing toothbrush and targeted mHealth micromessages: A randomized trial, Journal of Clinical Periodontology 2024;
- Zhang Zhaoqi, Zhao Xingru, Gao Shang, Li An, Deng Ke, Yang Kai, Liu Wei, Du Mi. Biological aging mediates the association between periodontitis and cardiovascular disease: results from a national population study and Mendelian randomization analysis, Clinical Epigenetics 2024; 16(1)
- Shi Xinyi, Zhu Peijun, Du Mi, Deng Ke, Li Ping, Sáenz-Ravello Gustavo, Xu Shulan, Li An. Dietary patterns and periodontitis: A systematic review, Journal of Periodontal Research 2024;
- Li An, Chen Yuntao, Du Mi, Deng Ke, Cui Xin, Lin Chunhua, Tjakkes Geerten-Has E, Zhuang Xiaodong, Hu Shixian. Healthy lifestyles ameliorate an increased risk of periodontitis associated with polycyclic aromatic hydrocarbons, Chemosphere 2024; 364
- Wei Xindi, Zhang Xiaomeng, Chen Ruiying, Li Yuan, Yang Yijie, Deng Ke, Cai Zhengzhen, Lai Hongchang, Shi Junyu. Impact of periodontitis on type 2 diabetes: a bioinformatic analysis, BMC Oral Health 2024; 24(1)
- Fu Xiao-Jiao, Liu Min, Shi Jun-Yu, Deng Ke, Lai Hong-Chang, Gu Wen, Zhang Xiao-Meng. Comparison of Different Intraoral Scanners With Prefabricated Aid on Accuracy and Framework Passive Fit of Digital Complete‐Arch Implant Impression: An In Vitro Study, Clinical Oral Implants Research 2024;
- Mei Lanzhuju, Deng Ke, Cui Zhiming, Fang Yu, Li Yuan, Lai Hongchang, Tonetti Maurizio S, Shen Dinggang. Clinical knowledge-guided hybrid classification network for automatic periodontal disease diagnosis in X-ray image, Medical Image Analysis 2024; 99
- Chen Jieyi, Deng Ke, Yu Dikuan, Fan Cancan, Liu Limin, Gu Haijing, Huang Fang, Huo Yongbiao. Recent Developments in the Non-Pharmacological Management of Children’s Behavior Based on Distraction Techniques: A Concise Review, Healthcare 2024; 12(19)
- Yang S, Chen J, Li A, Deng K, Li P, Xu S. Accuracy of autonomous robotic surgery for single-tooth implant placement: A case series, Journal of Dentistry 2023; 104451-104451
- Saenz-Ravello G, Matamala L, Cisternas P, Gamonal J, Hernandez P, Santos NCD, Deng K, Baeza M. Association between the Mediterranean Diet Index and self-reported Gingival Health Status Indicators in a population of Chilean adults: a cross-sectional study, Journal of Applied Oral Science 2023; 31
- Deng Ke, Zonta Francesco, Yang Huan, Pelekos George, Tonetti Maurizio S. Development of a machine learning multiclass screening tool for periodontal health status based on non-clinical parameters and salivary biomarkers, Journal of Clinical Periodontology 2023;
- Du Mi, Deng Ke, Cai Qingqing, Hu Shixian, Chen Yuntao, Xu Shulan, Tjakkes Geerten-Has E, Ge Shaohua, Ge Minghua, Li An. Mediating role of systemic inflammation in the association between heavy metals exposure and periodontitis risk., Journal of Periodontology 2023;
- Uy SNMR, Deng K, Fok TC, Fok MR, Pelekos G, Tonetti M. Food intake, masticatory function, tooth mobility, loss of posterior support, and diminished quality of life are associated with more advanced periodontitis stage diagnosis, Journal of Clinical Periodontology 2022; 49(3): 240-250
- Deng Ke, Uy Samantha N.M.R., Fok Chris, Fok Melissa R., Pelekos George, Tonetti Maurizio S.. Assessment of masticatory function in the differential diagnosis of Stage IV periodontitis: A pilot diagnostic accuracy study, Journal of Periodontology 2022; 93(6): 803-813
- Deng Ke, Wei Shimin, Xu Min, Shi Junyu, Lai Hongchang, Tonetti Maurizio S.. Diagnostic accuracy of active matrix metalloproteinase-8 point-of-care test for the discrimination of periodontal health status: Comparison of saliva and oral rinse samples, Journal of Periodontal Research 2022; 57(4): 768-779
- Shen Jie, Qian Shujiao, Huang Liyan, Tao Yang, Chen Hui, Deng Ke, Yang Fei, Zong Geng, Zheng Yan, Wang Xiaofeng, Tonetti Maurizio, Yuan Changzheng. Association of the number of natural teeth with dietary diversity and nutritional status in older adults: A cross-sectional study in China, Journal of Clinical Periodontology 2022;
- Wei Shi Min, Li Yuan, Deng Ke, Lai Hong Chang, Tonetti Maurizio S., Shi Jun Yu. Does machine-vision-assisted dynamic navigation improve the accuracy of digitally planned prosthetically guided immediate implant placement? A randomized controlled trial, Clinical Oral Implants Research 2022; 33(8): 804-815
- Qian Shu Jiao, Liu Beilei, Shi Junyu, Zhang Xiao, Deng Ke, Shen Jie, Tao Yang, Qiao Shichong, Lai Hong Chang, Yuan Changzheng, Tonetti Maurizio S.. Effects of Dental Implants and Nutrition on Elderly Edentulous Subjects: Protocol for a Factorial Randomized Clinical Trial, Frontiers in Nutrition 2022; 9: article no. 930023-article no. 930023
- Liu Wei, Qiu Wei, Huang Zhendong, Zhang Kaiying, Wu Keke, Deng Ke, Chen Yuanting, Guo Ruiming, Wu Buling, Chen Ting, Fang Fuchun. Identification of nine signature proteins involved in periodontitis by integrated analysis of TMT proteomics and transcriptomics, Frontiers in Immunology 2022; 13: article no. 963123-article no. 963123
- Ho DKL, Wong JHL, Pelekos G, Deng K, Tonetti MS. Prevalence and morphological characteristics of disto-lingual roots in mandibular first molars: a cone beam CT study with diagnostic and therapeutic implications, Clinical Oral Investigations 2021; 25(6): 4023-4030
- Tonetti MS, Cortellini P, Bonaccini D, Deng K, Cairo F, Allegri M, Conforti G, Graziani F, Guerrero A, Halben J, Malet J, Rasperini G, Topoll H. Autologous connective tissue graft or xenogenic collagen matrix with coronally advanced flaps for coverage of multiple adjacent gingival recession. 36‐month follow‐up of a randomized multicentre trial, Journal of Clinical Periodontology 2021; 48(7): 962-969
- Deng K, Pelekos G, Jin L, Tonetti M. Diagnostic accuracy of self‐reported measures of periodontal disease: A clinical validation study using the 2017 case definitions, Journal of Clinical Periodontology 2021; 48(8): 1037-1050
- Deng K, Pelekos G, Jin L, Tonetti MS. Diagnostic accuracy of a point‐of‐care aMMP‐8 test in the discrimination of periodontal health and disease, Journal of Clinical Periodontology 2021; 48(8): 1051-1065
- Deng K, Pelekos G, Jin L, Tonetti M. Gingival bleeding on brushing as a sentinel sign of gingival inflammation: A diagnostic accuracy trial for the discrimination of periodontal health and disease, Journal of Clinical Periodontology 2021; 48(12): 1537-1548
- Deng K, Pelekos G, Jin L, Tonetti M. Authors' Response: 'Diagnostic accuracy of a point‐of‐care aMMP‐8 test in the discrimination of periodontal health and disease', Journal of Clinical Periodontology 2021; 48(11): 1499-1500
- Tonetti MS, Deng K, Christiansen A, Bogetti K, Nicora C, Thurnay S, Cortellini P. Self‐reported bleeding on brushing as a predictor of bleeding on probing: Early observations from the deployment of an internet of things network of intelligent power‐driven toothbrushes in a supportive periodontal care population, Journal of Clinical Periodontology 2020; 47(10): 1219-1226
- Deng Ke, Ouyang Xiang Ying, Chu Yi, Zhang Qian. Subgingival Microbiome of Gingivitis in Chinese Undergraduates, The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA) 2017; 20(3): 145-152
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Book
- Xu Shulan, Yang Shuo, Li Ping, Li An, Li Shaobing, Chen Qiong, Tai Zhaoqiang, Dai Jingtao, Lin Yuankai, Deng Ke(Eds.). Robot-Assisted Dental Implant Surgery—Practical Skills and Typical Case Analysis. : Sichuan Science and Technology Press; 2024.
Conference Paper
- Yeung Jonathan Hok Kan, Zhan Xiangcheng, Lin Tingting, Qu Liangqiong, Fok Melissa, Deng Ke. Deep Learning for Automated Visualization and Measurement of Dental Plaque Using 3D Intraoral Scanning—A Cross-Sectional Study, Journal of Clinical Periodontology 2025; 52(S28)
- Mei Lanzhuju, Fang Yu, Cui Zhiming, Deng Ke, Wang Nizhuan, He Xuming, Zhan Yiqiang, Zhou Xiang, Tonetti Maurizio, Shen Dinggang. HC-Net: Hybrid Classification Network for Automatic Periodontal Disease Diagnosis, Lecture Notes in Computer Science 2023; 14225: 54-63
- Deng K, Du M, Li A. Chewing Capacity and Mortality Risk-The Mediation Role of Diet-related Aging, 2023 IADR/LAR General Session & Exhibition with WCPD (21/06/2023-24/06/2023, Bogotá, Colombia) 2023;
- Deng K, Pelekos G, Jin L, Tonetti M. Association of toothbrushing behaviour with periodontal health status among Hong Kong adults: a video-based observational study, EuroPerio10 2022; 49: 55-142
- Deng K, Pelekos G, Jin L, Tonetti M. Bleeding on brushing and slurry hemoglobin for identifying periodontal health/diseases, Journal of Dental Research (Spec Issue) 2021; 100(Spec Iss A): presentation ID 1729-presentation ID 1729
- Deng Ke, Pelekos Georgios, Jin Lijian, Tonetti Maurizio. A clinical validation study on self-reported measures for detecting periodontal diseases, The Annual Scientific Meeting, Faculty of Dentistry, The University of Hong Kong, Hong Kong (09/12/2020-09/12/2020, Hong Kong) 2020;
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- 2024. Deng K, Pelekos G, Jin L. Finalist of Joseph Lister Award for New Investigators Competition: 2024 IADR/AADOCR/CADR General Session & Exhibition.
- 2023. Deng K. Finalist of Joseph Lister Award for New Investigators Competition: 2023 IADR/APR General Session & Exhibition with WCPD.
- 2022. Deng K. Best paper award winner in 14th Periodontal Academic Conference, Society of Periodontology, Chinese Stomatological Association (CSA).
- 0000. Deng K. IADR Geriatric Oral Research Group Post-doctoral Award.
- 08 September 2025: Wong Hai Ming, Lam Pui Ying Phoebe, Tarce Mihai-Adrian, Deng Ke, Nalley Andrew Kyle, McGrath Colman, Rijkschroeff Patrick. 2025/26 KE Impact Project Funding: KE-IP-2025/26-13: Promoting Birth Registration through Dental Age Assessment and Improving Oral Health among Indigenous Communities in Palawan, the Philippines ($150,000).
- 25 August 2025: Deng Ke. 口齒生香：牙周炎 成人失牙主因.
- 08/2024-present: Board member. HKU Mainland Dental Alumni Association.
- 08/2023-present: member. Hong Kong Society of Periodontology and Implant Dentistry.
- 06/2022-present: member. Society of Periodontology, Chinese Stomatological Association.
- 05/2022-present: member. International Association of Dental Research.
- 02/2022-present: member. Hong Kong Dental Association.
- Project Title: Multi-modality deep learning for periodontal disease diagnosis: a multicentre discovery and validation study
Grant Type: General Research Fund (GRF) 2024/25
Funding Year: 2024
Amount: HK$1,528,251
Principal Investigator: Professor Deng, Ke
- Project Title: Porous metallic microneedle array-based test trip for gingival crevicular fluid collection and analysis
Grant Type: General Research Fund (GRF) 2024/25
Funding Year: 2024
Amount: HK$200,000
Principal Investigator: Professor Deng, Ke
- Project Title: Effect of the healthy plant-based dietary pattern as an adjunct to non-surgical periodontal treatment in periodontitis: a randomized controlled clinical trial
Grant Type: Health and Medical Research Fund 2022
Funding Year: 2023
Amount: HK$935,414
Principal Investigator: Professor Deng, Ke
Co-investigator(s): Professor Pelekos Georgios, Professor Leung Wai Keung
- Project Title: 3D-printed mouthguard with probiotic-encapsulated hydrogel as an adjuvant to periodontal treatment
Grant Type: Health and Medical Research Fund 2023
Funding Year: 2023
Amount: HK$1,476,300
Principal Investigator: Professor Ye, Zhou
Co-investigator(s): Professor McGrath Colman, Professor Huang Shi, Professor Deng Ke
- 17 June 2025: Advancements and Emerging Technologies in Periodontal Diagnosis. .
- 11 November 2024: 20th European Workshop on Periodontology Periodontal Diagnosis: Contemporary and Emerging Technologies. 20th European Workshop on Periodontology "Periodontal Diagnosis: Contemporary and Emerging Technologies" (10/11/2024-13/11/2024, La Granja de San Ildefonso, Spain).
- 23 October 2024: Innovative Diagnostic Techniques and Health Promotion for Periodontal Disease: Bridging to Healthy Longevity for HKSPID. October Seminar Jointly Organized by the Hong Kong Society of Periodontology and Implant Dentistry (HKSPID) and the Division of Periodontology and Implant Dentistry, Faculty of Dentistry, The University of Hong Kong (23/10/2024-23/10/2024, Hong Kong).
- 07 August 2024: Periodontal Immunology and Regeneration Academic Seminar by Medical School of Shenzhen University, School of Stomatology. Medical School of Shenzhen University, School of Stomatology (07/08/2024-07/08/2024).
- 22 June 2022: Large animal models for peri-implantitis for the focused learning session at the 2022 IADR/APR General Session & Exhibition. 2022 IADR/APR General Session & Exhibition (20/06/2022-25/06/2022, Virtual Conference).
- 01 December 2022-Present: Faculty of Dentistry, Board of the. The teachers who are members of the Faculty and who are full-time employees of the University
- All publication and awards data are automatically fetched periodically from the .
