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Professor Lee, Sang Jin

AS (DHC); BS (CUP); MS (KHU); PhD (KHU)

Professor Lee, Sang Jin - HKU Faculty of Dentistry 香港大學牙醫學院

Profile

Title
  • Assistant Professor in Biofunctional Materials
    生物功能材料學助理教授
Division
Applied Oral Sciences & Community Dental Care
E-mail
dentsj@hku.hk
Phone
+852 2859 0568
Biography
Professor Sangjin Lee is an assistant professor in the Division of Applied Oral Sciences and Community Dental Care at the Faculty of Dentistry, the University of Hong Kong (HKU). He obtained his BS from Catholic University of Pusan in 2012, his MS in 2014, and his PhD in 2017 from Kyung Hee University. He is engaged in research in dental tissue engineering and regenerative medicine, focusing on 1) oral and maxillofacial tissue regeneration using biomaterials, 2) 3D tissue organization using highly concentrated patient-derived stem cells, 3) the development of hydrogel-based composite grafts, and 4) the reconstruction of defective tissues through preclinical evaluation.
Research Theme
Craniofacial Regeneration
Areas of Research Expertise
  • 3D bioprinting
  • Electrospinning
  • Injectable hydrogel
  • Nano/microparticles
  • Stem cell therapy
  • Living tissue
Research Profile
Publication & Awards
Publications

    Article

  • Lee Sang Jin, Wu Zhenzhen, Huang Mengyu, Liang Chao, Huang Ziqi, Chen Siyuan, Rajasekar Vidhyashree, Abdalla Mohamed Mahmoud, Nah Haram, Heo Dong Nyoung, Kwon Il Keun, Cho Min Jai, Kim Seong Jun, Sohn Seil, Kim Su Hwan, Sugimura Ryohichi, Yiu Cynthia Kar Yung. Crosslinker-free in situ hydrogel induces self-aggregation of human dental pulp stem cells with enhanced antibacterial activity, Materials Today Bio 2025; 31 doi:10.1016/j.mtbio.2025.101451
  • Chan Rosalind Sin Man, Lee Sang Jin, Wang Fang, Zhou Tianyu, Kishan Ravi, Shum Ho Cheung, Yang Weifa, Su Yu-xiong, Tsoi James Kit Hon, Diwan Ashish D., Prusty B. Gangadhara, Cho Kiho. Engineered 3D-Printable Nanohydroxyapatite Biocomposites with Cold Plasma-Tailored Surface Features to Boost Osseointegration, ACS Applied Materials and Interfaces 2025; 17(16) doi:10.1021/acsami.4c22032
  • Lee Se-Hwan, Li Zizhao, Zhang Ellen Y, Kim Dong Hwa, Huang Ziqi, Heo Yuna, Lee Sang Jin, Kang Hyun-Wook, Burdick Jason A, Mauck Robert L, Heo Su Chin. Precision repair of zone-specific meniscal injuries using a tunable extracellular matrix-based hydrogel system, Bioactive Materials 2025; 48: 400-413 doi:10.1016/j.bioactmat.2025.02.013
  • Chen Siyuan, Wu Zhenzhen, Huang Ziqi, Liang Chao, Lee Sang Jin. Implantable Dental Barrier Membranes as Regenerative Medicine in Dentistry: A Comprehensive Review , Tissue Engineering and Regenerative Medicine 2025; 22(4): 527-546 doi:10.1007/s13770-025-00704-1
  • Ghosh Sumanta, Liang Chao, Lee Sang Jin, Qiao Wei. Engineering next-generation smart delivery materials for dentistry , Advances in Colloid and Interface Science 2025; 344 doi:10.1016/j.cis.2025.103607
  • Liang Chao, Wu Shuxuan, Huang Ziqi, Wu Zhenzhen, Chen Siyuan, Li Feiming, Kiang Karrie Mei-Yee, Leung Gilberto Ka-Kit, Jun Indong, Kim Hwan D., Cho Ann-Na, Lee Hee Jung, Park Honghyun, Leung Yiu Yan, Kim Seong Jun, Sohn Seil, Nah Haram, Lee Jae Seo, Kwon Il Keun, Heo Dong-Nyoung, Lee Sang-woo, Wu Zhaoming, Lee Sang Jin. Harnessing Oxidized Alginate Microgels for Rapid and Self‐Assembling Dental Tissue Organogenesis In Vitro and In Vivo, Small science 2025; 1-17 doi:10.1002/smsc.202500053
  • Lee Hyun, Won Dong Sung, Park Sinwoo, Park Yubeen, Kim Ji Won, Han Ginam, Na Yuhyun, Kang Min Ho, Kim Seok Beom, Kang Heemin, Park Jun Kyu, Jang Tae Sik, Lee Sang Jin, Park Su A, Lee Sang Soo, Park Jung Hoon, Jung Hyun Do. 3D-printed versatile biliary stents with nanoengineered surface for anti-hyperplasia and antibiofilm formation, Bioactive Materials 2024; 37: 172-190 doi:10.1016/j.bioactmat.2024.03.018
  • Lee Jae Seo, Kim Hyo Sung, Nah Haram, Moon Ho Jin, Ko Na Re, Lee Sang Jin, Ko Wan Kyu, Do Sun Hee, Heo Dong Nyoung, Kwon Il Keun. Bioinspired semi-flexible hydrogel with anti-inflammatory potential for natural tissue-mimicking bone regeneration, Composites Part B: Engineering 2024; 273 doi:10.1016/j.compositesb.2024.111223
  • Yang Dae Hyeok, Nah Haram, Lee Donghyun, Min Sung Jun, Park Seulki, An Sang Hyun, Wang Jianxin, He Huining, Choi Kyu Sun, Ko Wan Kyu, Lee Jae Seo, Kwon Il Keun, Lee Sang Jin, Heo Dong Nyoung. A review on gold nanoparticles as an innovative therapeutic cue in bone tissue engineering: Prospects and future clinical applications, Materials Today Bio 2024; 26 doi:10.1016/j.mtbio.2024.101016
  • Lee Sang Jin, Kim Han-Jun, Choi Eun Ji, Kim Hyosung, Lee Donghyun, An Sang-Hyun, Min Sung Jun, Ko Wan-Kyu, Lee Jae Seo, Nah Haram, Bang Jae Beum, Heo Min, Heo Dong Nyoung, Do Sun Hee, Kwon Il Keun. Immediately injectable modified gelatin and hyaluronic acid-based hydrogel encapsulating nano-hydroxyapatite and human adipose-derived MSCs for use as a bone filler in situ therapy, Carbohydrate Polymer Technologies and Applications 2024; 8 doi:10.1016/j.carpta.2024.100625
  • Choi Sumi, Kim Jung Hun, Kang Tae Hoon, An Young-Hyeon, Lee Sang Jin, Hwang Nathaniel S., Kim Su-Hwan. Biomimetic Marine-Sponge-Derived Spicule-Microparticle-Mediated Biomineralization and YAP/TAZ Pathway for Bone Regeneration In Vivo, Biomaterials Research 2024; 28 doi:10.34133/bmr.0056
  • Kim SH, Lee JS, Lee SJ, Nah H, Min SJ, Moon HJ, Bang JB, Kim HJ, Kim WJ, Kwon I, Heo DN . Development of a plasma-based 3D printing system for enhancing the biocompatibility of 3D scaffold, Biofabrication 2023; 15(3) doi:10.1088/1758-5090/acdf86
  • Ko Wan-Kyu, Nah Haram, Kim Seong Jun, Han Gong Ho, Lee Daye, Lee Jae Seo, Heo Dong Nyoung, Lee Donghyun, Lee Sang Jin, Heo Min, Sheen Seung Hun, Kwon Il Keun, Sohn Seil. The effects of aligned poly(lactic-co-glycolic acid) nanofibrous mat containing gold nanoparticles after planting onto an injured spinal cord, Materials & Design 2023; 232 doi:10.1016/j.matdes.2023.112181
  • Ding Aixiang, Lee Sang Jin, Ayyagari Sriramya, Tang Rui, Huynh Cong Truc, Alsberg Eben. 4D biofabrication via instantly generated graded hydrogel scaffolds, Bioactive Materials 2022; 7: 324-332 doi:10.1016/j.bioactmat.2021.05.021
  • Lee Daye, Nah Haram, Ko Wan Kyu, Jun Kim Seong, Han Gong Ho, Jeong Dabin, Lee Donghyun, Han Inbo, Sheen Seung Hun, Heo Dong Nyoung, Lee Sang Jin, Nam Yun Sik, Kwon Il Keun, Sohn Seil. Thiolate poly(lactic-co-glycolic acid) nanofibers loaded with dexamethasone and ropivacaine show enhanced sustained release in the treatment of neuropathic pain through a local therapy technique, Chemical Engineering Journal 2022; 431: article no. 133356-article no. 133356 doi:10.1016/j.cej.2021.133356
  • Jeon Oju, Lee Yu Bin, Lee Sang Jin, Guliyeva Nazilya, Lee Joanna, Alsberg Eben. Stem cell-laden hydrogel bioink for generation of high resolution and fidelity engineered tissues with complex geometries, Bioactive Materials 2022; 15: 185-193 doi:10.1016/j.bioactmat.2021.11.025
  • Ding Aixiang, Jeon Oju, Cleveland David, Gasvoda Kaelyn L., Wells Derrick, Lee Sang Jin, Alsberg Eben. Jammed Micro-Flake Hydrogel for Four-Dimensional Living Cell Bioprinting, Advanced Materials 2022; 34(15): article no. 2109394-article no. 2109394 doi:10.1002/adma.202109394
  • Ko Wan Kyu, Kim Seong Jun, Han Gong Ho, Lee Daye, Jeong Dabin, Lee Sang Jin, Han In Bo, Hong Je Beom, Sheen Seung Hun, Sohn Seil. Transplantation of neuron-inducing grafts embedding positively charged gold nanoparticles for the treatment of spinal cord injury, Bioengineering and Translational Medicine 2022; 7(3): article no. e10326-article no. e10326 doi:10.1002/btm2.10326
  • Seo Lee Jae, Nah Haram, Lee Donghyun, An Sang Hyun, Ko Wan Kyu, Lee Sang Jin, Yeon Lee Seung, Min Park Kyung, Bok Lee Jung, Yi Hyeong joong, Keun Kwon Il, Choi Kyu Sun, Nyoung Heo Dong. Immediately implantable extracellular matrix-enriched osteoinductive hydrogel-laden 3D-printed scaffold for promoting vascularized bone regeneration in vivo, Materials and Design 2022; 219: article no. 110801-article no. 110801 doi:10.1016/j.matdes.2022.110801
  • Ding Aixiang, Lee Sang Jin, Tang Rui, Gasvoda Kaelyn L., He Felicia, Alsberg Eben. 4D Cell-Condensate Bioprinting, Small 2022; 18(36): article no. 2202196-article no. 2202196 doi:10.1002/smll.202202196
  • Lee JM, Jeon O, Koh J, Kim HJ, Lee SJ, Zhu YZ, Song JHY, Lee YJ, Nasiri R, Lee KJ, Bandaru P, Cho HJ, Zhang SM, Barros NR, Ahadian S, Kang HM, Dokmeci MR, Lee JN, Di Carlo D, Alsberg E, Khademhosseini A. Micromechanical property mismatch between pericellular and extracellular matrices regulates stem cell articular and hypertrophic chondrogenesis, Matter 2022; 6(2): 475-492 doi:10.1016/j.matt.2022.11.008
  • Ding Aixiang, Jeon Oju, Tang Rui, Lee Yu Bin, Lee Sang Jin, Alsberg Eben. Cell-Laden Multiple-Step and Reversible 4D Hydrogel Actuators to Mimic Dynamic Tissue Morphogenesis, Advanced Science 2021; 8(9): article no. 2004616-article no. 2004616 doi:10.1002/advs.202004616
  • Lee Yu Bin, Jeon Oju, Lee Sang Jin, Ding Aixiang, Wells Derrick, Alsberg Eben. Induction of Four-Dimensional Spatiotemporal Geometric Transformations in High Cell Density Tissues via Shape-Changing Hydrogels, Advanced Functional Materials 2021; 31(24): article no. 2010104-article no. 2010104 doi:10.1002/adfm.202010104
  • Seok Ji Min, Jeong Jae Eun, Lee Sang Jin, Im Seung Hyun, Lee Jun Hee, Kim Wan Doo, Lee Kangwon, Park Su A.. Bio-plotted hydrogel scaffold with core and sheath strand-enhancing mechanical and biological properties for tissue regeneration, Colloids and Surfaces B: Biointerfaces 2021; 205: article no. 111919-article no. 111919 doi:10.1016/j.colsurfb.2021.111919
  • Ko Wan Kyu, Lee Sang Jin, Kim Seong Jun, Han Gong Ho, Han In Bo, Hong Je Beom, Sheen Seung Hun, Sohn Seil. Direct Injection of Hydrogels Embedding Gold Nanoparticles for Local Therapy after Spinal Cord Injury, Biomacromolecules 2021; 22(7): 2887-2901 doi:10.1021/acs.biomac.1c00281
  • Seok Ji Min, Choe Goeun, Lee Sang Jin, Yoon Min Ah, Kim Kwang Seop, Lee Jun Hee, Kim Wan Doo, Lee Jae Young, Lee Kangwon, Park Su A.. Enhanced three-dimensional printing scaffold for osteogenesis using a mussel-inspired graphene oxide coating, Materials and Design 2021; 209: article no. 109941-article no. 109941 doi:10.1016/j.matdes.2021.109941
  • Lee Sang Jin, Nah Haram, Ko Wan Kyu, Lee Donghyun, Moon Ho Jin, Lee Jae Seo, Heo Min, Hwang Yu Shik, Bang Jae Beum, An Sang Hyun, Heo Dong Nyoung, Kwon Il Keun. Facile Preparation of β-Cyclodextrin-grafted Chitosan Electrospun Nanofibrous Scaffolds as a Hydrophobic Drug Delivery Vehicle for Tissue Engineering Applications, ACS Omega 2021; 6(42): 28307-28315 doi:10.1021/acsomega.1c04481
  • Lee Jae Seo, Kim Hyo Sung, Nah Haram, Lee Sang Jin, Moon Ho Jin, Bang Jae Beum, Lee Jung Bok, Do Sun Hee, Kwon Il Keun, Heo Dong Nyoung. The effectiveness of compartmentalized bone graft sponges made using complementary bone graft materials and succinylated chitosan hydrogels, Biomedicines 2021; 9(12): article no. 1765-article no. 1765 doi:10.3390/biomedicines9121765
  • Choi Ji Suk, Huh Beom Kang, Lee Sang Jin, Han Mi Jung, Eom Min Rye, Ahn Hee Jin, Jin Young Ju, Park Su A., Choy Young Bin, Kwon Seong Keun. Tranilast-loaded tubular scaffold and surgical suture for suppression of stenosis after tracheal prosthesis transplantation, Journal of Industrial and Engineering Chemistry 2020; 82: 81-88 doi:10.1016/j.jiec.2019.09.045
  • Heo Dong Nyoung, Kim Han Jun, Lee Donghyun, Kim Hyosung, Lee Sang Jin, Lee Hye Rim, Kwon Il Keun, Do Sun Hee. Comparison of polysaccharides in articular cartilage regeneration associated with chondrogenic and autophagy-related gene expression, International Journal of Biological Macromolecules 2020; 146: 922-930 doi:10.1016/j.ijbiomac.2019.09.215
  • Lee Sang Jin, Choi Ji Suk, Eom Min Rye, Jo Ha Hyeon, Kwon Il Keun, Kwon Seong Keun, Park Su A.. Dexamethasone loaded bilayered 3D tubular scaffold reduces restenosis at the anastomotic site of tracheal replacement: In vitro and in vivo assessments, Nanoscale 2020; 12(8): 4846-4858 doi:10.1039/c9nr10341d
  • Kim In Gul, Park Su A., Lee Shin Hyae, Choi Ji Suk, Cho Hana, Lee Sang Jin, Kwon Yoo Wook, Kwon Seong Keun. Transplantation of a 3D-printed tracheal graft combined with iPS cell-derived MSCs and chondrocytes, Scientific Reports 2020; 10(1): article no. 4326-article no. 4326 doi:10.1038/s41598-020-61405-4
  • Lee Junmin, Jeon Oju, Kong Ming, Abdeen Amr A., Shin Jung Youn, Lee Ha Neul, Lee Yu Bin, Sun Wujin, Bandaru Praveen, Alt Daniel S., Lee Kang Ju, Kim Han Jun, Lee Sang Jin, Chaterji Somali, Shin Su Ryon, Alsberg Eben, Khademhosseini Ali. Combinatorial screening of biochemical and physical signals for phenotypic regulation of stem cell-based cartilage tissue engineering, Science Advances 2020; 6(21): article no. EAAZ5913-article no. EAAZ5913 doi:10.1126/sciadv.aaz5913
  • Nah Haram, Lee Donghyun, Lee Jae Seo, Lee Sang Jin, Heo Dong Nyoung, Lee Yeon Hee, Bang Jae Beum, Hwang Yu Shik, Moon Ho Jin, Kwon Il Keun. Strategy to inhibit effective differentiation of RANKL-induced osteoclasts using vitamin D-conjugated gold nanoparticles, Applied Surface Science 2020; 527: article no. 146765-article no. 146765 doi:10.1016/j.apsusc.2020.146765
  • Lee Jae Seo, Nah Haram, Moon Ho Jin, Lee Sang Jin, Heo Dong Nyoung, Kwon Il Keun. Controllable delivery system: A temperature and pH-responsive injectable hydrogel from succinylated chitosan, Applied Surface Science 2020; 528: article no. 146812-article no. 146812 doi:10.1016/j.apsusc.2020.146812
  • Lee Sang Jin, Nah Haram, Heo Dong Nyoung, Kim Kyoung Hwa, Seok Ji Min, Heo Min, Moon Ho Jin, Lee Donghyun, Lee Jae Seo, An Seong Yeong, Hwang Yu Shik, Ko Wan Kyu, Kim Seong Jun, Sohn Seil, Park Su A., Park Shin Young, Kwon Il Keun. Induction of osteogenic differentiation in a rat calvarial bone defect model using an In situ forming graphene oxide incorporated glycol chitosan/oxidized hyaluronic acid injectable hydrogel, Carbon 2020; 168: 264-277 doi:10.1016/j.carbon.2020.05.022
  • Lee Sang Jin, Kim Mi Eun, Nah Haram, Seok Ji Min, Jeong Myung Ho, Park Kwangsung, Kwon Il Keun, Lee Jun Sik, Park Su A.. Vascular endothelial growth factor immobilized on mussel-inspired three-dimensional bilayered scaffold for artificial vascular graft application: In vitro and in vivo evaluations, Journal of Colloid and Interface Science 2019; 537: 333-344 doi:10.1016/j.jcis.2018.11.039
  • Seok Ji Min, Oh Se Heang, Lee Sang Jin, Lee Jun Hee, Kim Wan Doo, Park Sang Hyug, Nam Seung Yun, Shin Heungsoo, Park Su A.. Fabrication and characterization of 3D scaffolds made from blends of sodium alginate and poly(vinyl alcohol), Materials Today Communications 2019; 19: 56-61 doi:10.1016/j.mtcomm.2018.09.013
  • Lee Sang Jin, Won Jong Eun, Han Changhak, Yin Xiang Yun, Kim Hyung Keun, Nah Haram, Kwon Il Keun, Min Byoung Hyun, Kim Chul Ho, Shin Yoo Seob, Park Su A.. Development of a three-dimensionally printed scaffold grafted with bone forming peptide-1 for enhanced bone regeneration with in vitro and in vivo evaluations, Journal of Colloid and Interface Science 2019; 539: 468-480 doi:10.1016/j.jcis.2018.12.097
  • Lee Donghyun, Choi Eun Ji, Lee Si Eun, Kang Kyung Lhi, Moon Ho Jin, Kim Han Jun, Youn Yun Hee, Heo Dong Nyoung, Lee Sang Jin, Nah Haram, Hwang Yu Shik, Lee Yeon Hee, Seong Jeongmin, Do Sun Hee, Kwon Il Keun. Injectable biodegradable gelatin-methacrylate/Β‐tricalcium phosphate composite for the repair of bone defects, Chemical Engineering Journal 2019; 365: 30-39 doi:10.1016/j.cej.2019.02.020
  • Youn Yun Hee, Lee Sang Jin, Choi Go Ro, Lee Hak Rae, Lee Donghyun, Heo Dong Nyong, Kim Byung Soo, Bang Jae Beum, Hwang Yu Shik, Correlo Vitor M., Reis Rui L., Im Sung Gap, Kwon Il Keun. Simple and facile preparation of recombinant human bone morphogenetic protein-2 immobilized titanium implant via initiated chemical vapor deposition technique to promote osteogenesis for bone tissue engineering application, Materials Science and Engineering C 2019; 100: 949-958 doi:10.1016/j.msec.2019.03.048
  • Lee Sang Jin, Kim Han Jun, Heo Min, Lee Hye Rim, Choi Eun Ji, Kim Hyosung, Lee Donghyun, Reis Rui L., Do Sun Hee, Kwon Il Keun. In vitro and in vivo assessments of an optimal polyblend composition of polycaprolactone/gelatin nanofibrous scaffolds for Achilles tendon tissue engineering, Journal of Industrial and Engineering Chemistry 2019; 76: 173-180 doi:10.1016/j.jiec.2019.03.036
  • Kim Seong Jun, Ko Wan Kyu, Heo Dong Nyoung, Lee Sang Jin, Lee Donghyun, Heo Min, Han In Bo, Kwon Il Keun, Sohn Seil. Anti-neuroinflammatory gold nanocomplex loading ursodeoxycholic acid following spinal cord injury, Chemical Engineering Journal 2019; 375: article no. 122088-article no. 122088 doi:10.1016/j.cej.2019.122088
  • Lee Sang Jin, Jo Ha Hyeon, Lim Kyung Seob, Lim Dohyung, Lee Soojin, Lee Jun Hee, Kim Wan Doo, Jeong Myung Ho, Lim Joong Yeon, Kwon Il Keun, Jung Youngmee, Park Jun Kyu, Park Su A.. Heparin coating on 3D printed poly (l-lactic acid) biodegradable cardiovascular stent via mild surface modification approach for coronary artery implantation, Chemical Engineering Journal 2019; 378: article no. 122116-article no. 122116 doi:10.1016/j.cej.2019.122116
  • Nah Haram, Lee Donghyun, Heo Min, Lee Jae Seo, Lee Sang Jin, Heo Dong Nyoung, Seong Jeongmin, Lim Ho Nam, Lee Yeon Hee, Moon Ho Jin, Hwang Yu Shik, Kwon Il Keun. Vitamin D-conjugated gold nanoparticles as functional carriers to enhancing osteogenic differentiation, Science and Technology of Advanced Materials 2019; 20(1): 826-836 doi:10.1080/14686996.2019.1644193
  • Lee Jae Seo, Lee Sang Jin, Yang Seok Bin, Lee Donghyun, Nah H., Heo Dong Nyoung, Moon Ho Jin, Hwang Yu Shik, Reis R. L., Moon Ji Hoi, Kwon Il Keun. Facile preparation of mussel-inspired antibiotic-decorated titanium surfaces with enhanced antibacterial activity for implant applications, Applied Surface Science 2019; 496: article no. 143675-article no. 143675 doi:10.1016/j.apsusc.2019.143675
  • Jeon Oju, Lee Yu Bin, Jeong Hyoen, Lee Sang Jin, Wells Derrick, Alsberg Eben. Individual cell-only bioink and photocurable supporting medium for 3D printing and generation of engineered tissues with complex geometries, Materials Horizons 2019; 6(8): 1625-1631 doi:10.1039/c9mh00375d
  • Lee Sang Jin, Heo Min, Lee Donghyun, Han Seungheui, Moon Ji Hoi, Lim Ho Nam, Kwon Il Keun. Preparation and characterization of antibacterial orthodontic resin containing silver nanoparticles, Applied Surface Science 2018; 432: 317-323 doi:10.1016/j.apsusc.2017.04.030
  • Heo Min, Lee Sang Jin, Heo Dong Nyoung, Lee Donghyun, Lim Ho Nam, Moon Ji Hoi, Kwon Il Keun. Multilayered co-electrospun scaffold containing silver sulfadiazine as a prophylactic against osteomyelitis: Characterization and biological in vitro evaluations, Applied Surface Science 2018; 432: 308-316 doi:10.1016/j.apsusc.2017.04.147
  • Lee Donghyun, Heo Dong Nyoung, Lee Sang Jin, Heo Min, Kim Jeongho, Choi Samjin, Park Hun Kuk, Park Young Guk, Lim Ho Nam, Kwon Il Keun. Poly(lactide-co-glycolide) nanofibrous scaffolds chemically coated with gold-nanoparticles as osteoinductive agents for osteogenesis, Applied Surface Science 2018; 432: 300-307 doi:10.1016/j.apsusc.2017.05.237
  • Jang Kee W., Seol Dongrim, Ding Lei, Heo Dong Nyoung, Lee Sang Jin, Martin James A., Kwon Il Keun. Ultrasound-triggered PLGA microparticle destruction and degradation for controlled delivery of local cytotoxicity and drug release, International Journal of Biological Macromolecules 2018; 106: 1211-1217 doi:10.1016/j.ijbiomac.2017.08.125
  • Park Su A., Lee Hyo Jung, Kim Keun Suh, Lee Sang Jin, Lee Jung Tae, Kim Sung Yeol, Chang Na Hee, Park Shin Young. In vivo evaluation of 3D-printed polycaprolactone scaffold implantation combined with β-TCP powder for alveolar bone augmentation in a beagle defect model, Materials 2018; 11(2): article no. 238-article no. 238 doi:10.3390/ma11020238
  • Park Su A., Lee Sang Jin, Seok Ji Min, Lee Jun Hee, Kim Wan Doo, Kwon Il Keun. Fabrication of 3D Printed PCL/PEG Polyblend Scaffold Using Rapid Prototyping System for Bone Tissue Engineering Application, Journal of Bionic Engineering 2018; 15(3): 435-442 doi:10.1007/s42235-018-0034-8
  • Lee Donghyun, Lee Sang Jin, Moon Ji Hoi, Kim Joo Hyoung, Heo Dong Nyoung, Bang Jae Beum, Lim Ho Nam, Kwon Il Keun. Preparation of antibacterial chitosan membranes containing silver nanoparticles for dental barrier membrane applications, Journal of Industrial and Engineering Chemistry 2018; 66: 196-202 doi:10.1016/j.jiec.2018.05.030
  • Lee Sang Jin, Lee Hyo Jung, Kim Sung Yeol, Seok Ji Min, Lee Jun Hee, Kim Wan Doo, Kwon Il Keun, Park Shin Young, Park Su A.. In situ gold nanoparticle growth on polydopamine-coated 3D-printed scaffolds improves osteogenic differentiation for bone tissue engineering applications: In vitro and in vivo studies, Nanoscale 2018; 10(33): 15447-15453 doi:10.1039/c8nr04037k
  • Lee Donghyun, Heo Dong Nyoung, Nah Ha Ram, Lee Sang Jin, Ko Wan Kyu, Lee Jae Seo, Moon Ho Jin, Bang Jae Beum, Hwang Yu Shik, Reis Rui L., Kwon Il Keun. Injectable hydrogel composite containing modified gold nanoparticles: Implication in bone tissue regeneration, International Journal of Nanomedicine 2018; 13: 7019-7031 doi:10.2147/IJN.S185715
  • Heo Eun Young, Ko Na Re, Bae Min Soo, Lee Sang Jin, Choi Byung Joon, Kim Jung Ho, Kim Hyung Keun, Park Su A., Kwon Il Keun. Novel 3D printed alginate–BFP1 hybrid scaffolds for enhanced bone regeneration, Journal of Industrial and Engineering Chemistry 2017; 45: 61-67 doi:10.1016/j.jiec.2016.09.003
  • Park Jisun, Lee Sang Jin, Chung Solchan, Lee Jun Hee, Kim Wan Doo, Lee Jae Young, Park Su A.. Cell-laden 3D bioprinting hydrogel matrix depending on different compositions for soft tissue engineering: Characterization and evaluation, Materials Science and Engineering C 2017; 71: 678-684 doi:10.1016/j.msec.2016.10.069
  • Lee Sang Jin, Bae Min Soo, Lee Deok Won, Heo Dong Nyoung, Lee Donghyun, Heo Min, Hong Seoung Jin, Kim Joohyoung, Kim Wan Doo, Park Su A., Kwon Il Keun. The use of heparin chemistry to improve dental osteogenesis associated with implants, Carbohydrate Polymers 2017; 157: 1750-1758 doi:10.1016/j.carbpol.2016.11.062
  • Park J., Lee Sang Jin, Jo Ha Hyeon, Lee Jun Hee, Kim Wan Doo, Lee Jae Young, Park Su A.. Fabrication and characterization of 3D-printed bone-like β-tricalcium phosphate/polycaprolactone scaffolds for dental tissue engineering, Journal of Industrial and Engineering Chemistry 2017; 46: 175-181 doi:10.1016/j.jiec.2016.10.028
  • Lee Sang Jin, Heo Dong Nyoung, Heo Min, Noh Mi Hee, Lee Donghyun, Park Su A., Moon Ji Hoi, Kwon Il Keun. Most simple preparation of an inkjet printing of silver nanoparticles on fibrous membrane for water purification: Technological and commercial application, Journal of Industrial and Engineering Chemistry 2017; 46: 273-278 doi:10.1016/j.jiec.2016.10.039
  • Lee Sang Jin, Heo Min, Lee Donghyun, Heo Dong Nyoung, Lim Ho Nam, Kwon Il Keun. Fabrication and design of bioactive agent coated, highly-aligned electrospun matrices for nerve tissue engineering: Preparation, characterization and application, Applied Surface Science 2017; 424: 359-367 doi:10.1016/j.apsusc.2017.02.179
  • Heo Dong Nyoung, Kim Han Jun, Lee Yi Jae, Heo Min, Lee Sang Jin, Lee Donghyun, Do Sun Hee, Lee Soo Hyun, Kwon Il Keun. Flexible and Highly Biocompatible Nanofiber-Based Electrodes for Neural Surface Interfacing, ACS Nano 2017; 11(3): 2961-2971 doi:10.1021/acsnano.6b08390
  • Kim Han Jun, Heo Dong Nyoung, Lee Yi Jae, Lee Sang Jin, Kang Ji Yoon, Lee Soo Hyun, Kwon Ii Keun, Do Sun Hee. Biological assessments of multifunctional hydrogel-decorated implantable neural cuff electrode for clinical neurology application, Scientific Reports 2017; 7(1): article no. 15245-article no. 15245 doi:10.1038/s41598-017-15551-x
  • Heo Min, Lee Sang Jin, Lee Donghyun, Heo Dong Nyoung, Lee Jae Seo, Youn Yun Hee, Lee Si Eun, Ko Na Re, Kim Byung Soo, Lim Ho Nam, Kwon Il Keun. Preparation of mechanically enhanced hydrogel scaffolds by incorporating interfacial polymer nanorods for nerve electrode application, Fibers and Polymers 2017; 18(11): 2248-2254 doi:10.1007/s12221-017-7456-5
  • Lee Sang Jin, Heo Dong Nyoung, Lee Donghyun, Heo Min, Rim Hyunjoon, Zhang Lijie Grace, Park Su A., Do Sun Hee, Moon Ji Hoi, Kwon Il Keun. One-step fabrication of AgNPs embedded hybrid dual nanofibrous oral wound dressings, Journal of Biomedical Nanotechnology 2016; 12(11): 2041-2050 doi:10.1166/jbn.2016.2304
  • Lee Sang Jin, Lee Donghyun, Yoon Taek Rim, Kim Hyung Keun, Jo Ha Hyeon, Park Ji Sun, Lee Jun Hee, Kim Wan Doo, Kwon Il Keun, Park Su A.. Surface modification of 3D-printed porous scaffolds via mussel-inspired polydopamine and effective immobilization of rhBMP-2 to promote osteogenic differentiation for bone tissue engineering, Acta Biomaterialia 2016; 40: 182-191 doi:10.1016/j.actbio.2016.02.006
  • Heo Dong Nyoung, Ko Wan Kyu, Lee Hak Rae, Lee Sang Jin, Lee Donghyun, Um Soong Ho, Lee Jung Haeng, Woo Yi Hyung, Zhang Lijie Grace, Lee Deok Won, Kwon Il Keun. Titanium dental implants surface-immobilized with gold nanoparticles as osteoinductive agents for rapid osseointegration, Journal of Colloid and Interface Science 2016; 469: 129-137 doi:10.1016/j.jcis.2016.02.022
  • Lee Sang Jin, Jo Ha Hyeon, Kwon Seong Keun, Lee Jin Ho, Kim Wan Doo, Lee Jun Hee, Kwon Il Keun, Park Su A.. A novel mussel-inspired 3D printed-scaffolds immobilized with bone forming peptide-1 for bone tissue engineering applications: Preparation, characterization and evaluation of its properties, Macromolecular Research 2016; 24(4): 305-308 doi:10.1007/s13233-016-4049-x
  • Heo Dong Nyoung, Song Su Jin, Kim Han Jun, Lee Yi Jae, Ko Wan Kyu, Lee Sang Jin, Lee Donghyun, Park Sung Jin, Zhang Lijie Grace, Kang Ji Yoon, Do Sun Hee, Lee Soo Hyun, Kwon Il Keun. Multifunctional hydrogel coatings on the surface of neural cuff electrode for improving electrode-nerve tissue interfaces, Acta Biomaterialia 2016; 39: 25-33 doi:10.1016/j.actbio.2016.05.009
  • Lee Donghyun, Heo Dong Nyoung, Kim Han Jun, Ko Wan Kyu, Lee Sang Jin, Heo Min, Bang Jae Beum, Lee Jung Bok, Hwang Deok Sang, Do Sun Hee, Kwon Il Keun. Inhibition of Osteoclast Differentiation and Bone Resorption by Bisphosphonate-conjugated Gold Nanoparticles, Scientific Reports 2016; 6: article no. 27336-article no. 27336 doi:10.1038/srep27336
  • Park S. E., Ko Wan Kyu, Park Jae Hyun, Bayome Mohamed, Park Justyn, Heo Dong Nyoung, Lee Sang Jin, Moon Ji Hoi, Kwon Il Keun, Kook Yoon Ah. Antibacterial effect of silver and gold nanoparticle coated modified C-palatal plate, Journal of Nanoscience and Nanotechnology 2016; 16(8): 8809-8813 doi:10.1166/jnn.2016.12497
  • Lee Sang Jin, Park Su A., Heo Dong Nyoung, Lee Donghyun, Jang Hee Jae, Kim Ki Seok, Moon Ji Hoi, Kwon Il Keun. Preparation of electrospun fibrous scaffold containing silver sulfadiazine for biomedical applications, Journal of Nanoscience and Nanotechnology 2016; 16(8): 8554-8558 doi:10.1166/jnn.2016.12481
  • Heo Dong Nyoung, Ko Wan Kyu, Lee Won Jun, Lee Sang Jin, Lee Donghyun, Heo Min, Rim Hyunjoon, Bae Min Soo, Lee Jung Bok, Ahn Byung Seob, Kwon Il Keun. Enhanced biocompatibility of polyimide film by anti-inflammatory drug loading, Journal of Nanoscience and Nanotechnology 2016; 16(8): 8800-8804 doi:10.1166/jnn.2016.12482
  • Bae Min Soo, Ko Na Re, Lee Sang Jin, Lee Jung Bok, Heo Dong Nyoung, Byun Wook, Choi Byung Joon, Jeon Hoon Bong, Jang Hee Jae, Ahn Ji Yoon, Hwang Deok Sang, Jung Bock Young, Kwon Il Keun. Development of novel photopolymerizable hyaluronic acid/heparin-based hydrogel scaffolds with a controlled release of growth factors for enhanced bone regeneration, Macromolecular Research 2016; 24(9): 829-837 doi:10.1007/s13233-016-4112-7
  • Lee Doh Young, Park Su A., Lee Sang Jin, Kim Tae Ho, Oh Se Heang, Lee Jin Ho, Kwon Seong Keun. Segmental tracheal reconstruction by 3D-printed scaffold: Pivotal role of asymmetrically porous membrane, Laryngoscope 2016; 126(9): E304-E309 doi:10.1002/lary.25806
  • Lee Donghyun, Ko Wan Kyu, Hwang Deok Sang, Heo Dong Nyoung, Lee Sang Jin, Heo Min, Lee Kook Sun, Ahn Ji Yoon, Jo Junyoung, Kwon Il Keun. Use of Baicalin-Conjugated Gold Nanoparticles for Apoptotic Induction of Breast Cancer Cells, Nanoscale Research Letters 2016; 11(1): article no. 381-article no. 381 doi:10.1186/s11671-016-1586-3
  • Jo Ha Hyeon, Lee Sang Jin, Park Ji Sun, Lee Jun Hee, Kim Wan Doo, Kwon Seong Keun, Lee Jin Ho, Lim Joong Yeon, Park Su A.. Characterization and preparation of three-dimensional-printed biocompatible scaffolds with highly porous strands, Journal of Nanoscience and Nanotechnology 2016; 16(11): 11943-11946 doi:10.1166/jnn.2016.13622
  • Ko Wan Kyu, Heo Dong Nyoung, Moon Ho Jin, Lee Sang Jin, Bae Min Soo, Lee Jung Bok, Sun In Cheol, Jeon Hoon Bong, Park Hun Kuk, Kwon Il Keun. The effect of gold nanoparticle size on osteogenic differentiation of adipose-derived stem cells, Journal of Colloid and Interface Science 2015; 438: 68-76 doi:10.1016/j.jcis.2014.08.058
  • Park Se Woong, Lee Donghyun, Lee Hak Rae, Moon Ho Jin, Lee Bo Ra, Ko Wan Kyu, Song Su Jin, Lee Sang Jin, Shin Kwanwoo, Jang Wonhyeong, Yi Jin Kyu, Im Sung Gap, Kwon Il Keun. Generation of functionalized polymer nanolayer on implant surface via initiated chemical vapor deposition (iCVD), Journal of Colloid and Interface Science 2015; 439: 34-41 doi:10.1016/j.jcis.2014.10.018
  • Park Su A., Lee Sang Jin, Lim Kyung Seob, Bae In Ho, Lee Jun Hee, Kim Wan Doo, Jeong Myung Ho, Park Jun Kyu. In vivo evaluation and characterization of a bio-absorbable drug-coated stent fabricated using a 3D-printing system, Materials Letters 2015; 141: 355-358 doi:10.1016/j.matlet.2014.11.119
  • Lee Sang Jin, Heo Dong Nyoung, Park Ji Sun, Kwon Seong Keun, Lee Jin Ho, Lee Jun Hee, Kim Wan Doo, Kwon Il Keun, Park Su A.. Characterization and preparation of bio-tubular scaffolds for fabricating artificial vascular grafts by combining electrospinning and a 3D printing system, Physical Chemistry Chemical Physics 2015; 17(5): 2996-2999 doi:10.1039/c4cp04801f
  • Lee Sang Jin, Heo Dong Nyoung, Lee Hak Rae, Lee Donghyun, Yu Seung Jung, Park Su A., Ko Wan Kyu, Park Se Woong, Im Sung Gap, Moon Ji Hoi, Kwon Il Keun. Biofunctionalized titanium with anti-fouling resistance by grafting thermo-responsive polymer brushes for the prevention of peri-implantitis, Journal of Materials Chemistry B 2015; 3(26): 5161-5165 doi:10.1039/c5tb00611b
  • Lee Sang Jin, Heo Dong Nyoung, Moon Ji Hoi, Ko Wan Kyu, Lee Jung Bok, Bae Min Soo, Park Se Woong, Kim Ji Eun, Lee Dong Hyun, Kim Eun Cheol, Lee Chang Hoon, Kwon Il Keun. Electrospun chitosan nanofibers with controlled levels of silver nanoparticles. Preparation, characterization and antibacterial activity, Carbohydrate Polymers 2014; 111: 530-537 doi:10.1016/j.carbpol.2014.04.026
  • Lee Sang Jin, Heo Dong Nyoung, Moon Ji Hoi, Park Ha Na, Ko Wan Kyu, Bae Min Soo, Lee Jung Bok, Park Se Woong, Kim Eun Cheol, Lee Chang Hoon, Jung Bock Young, Kwon Il Keun. Chitosan/polyurethane blended fiber sheets containing silver sulfadiazine for use as an antimicrobial wound dressing, Journal of Nanoscience and Nanotechnology 2014; 14(10): 7488-7494 doi:10.1166/jnn.2014.9581
  • Heo Dong Nyoung, Ko Wan Kyu, Moon Ho Jin, Kim Han Jun, Lee Sang Jin, Lee Jung Bok, Bae Min Soo, Yi Jin Kyu, Hwang Yu Shik, Bang Jae Beum, Kim Eun Cheol, Do Sun Hee, Kwon Il Keun. Inhibition of osteoclast differentiation by gold nanoparticles functionalized with cyclodextrin curcumin complexes, ACS Nano 2014; 8(12): 12049-12062 doi:10.1021/nn504329u
  • Park Dong Jin, Lee Sang Jin, Lee Sang Cheon. 카테콜 함유 생체모방 점막접착형 고분자의 합성 및 특성 연구, 폴리머 2013; 37(5): 625-631 doi:10.7317/pk.2013.37.5.625
  • Lee Sang Jin, Min Kyung Hyun, Lee Hong Jae, Koo Ahn Na, Rim Hwa Pyeong, Jeon Byeong Jin, Jeong Seo Young, Heo Jung Sun, Lee Sang Cheon. Ketal cross-linked poly(ethylene glycol)-poly(amino acid)s copolymer micelles for efficient intracellular delivery of doxorubicin, Biomacromolecules 2011; 12(4): 1224-1233 doi:10.1021/bm101517x

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    Conference Paper

  • Chan Sin Man, Lee Sangjin, Wang Fang, Shum Ho Cheung Anderson, Tsoi, Kit Hon, Cho, Kiho. Biomechanically Advanced Polymer-Based Biocomposites for Oral and Maxillofacial Reconstruction, 2024 IADR/AADOCR/CADR General Session (13/03/2024-16/03/2024, New Orleans, Louisiana) 2024;
  • Lee Yu Bin, Jeon Oju, Jeong Hyeon, Lee Sang Jin, Alsberg Eben. Living cell-only bioprinting for regenerative medicine, Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium 2019; 40: 141-
Honours & Awards
  • 2025. Lee S. As the Best Reviewer in 2024 for the journal of Bioactive Materials.
Grants
  • Project Title: 3D-Printed Metal-Reinforced Biocomposite with Hydrogel for Jaw Reconstruction
    Grant Type: AO CMF Start-up Grants 2025
    Funding Year: 2025
    Amount: HK$481,457
    Principal Investigator: Professor Pu, Jingya
    Co-investigator(s): Professor Lee Sangjin, Professor Su Yuxiong, Professor Cho Kiho
Invited Lectures & Keynote Speeches
  • 23 July 2025: Research on tissue-engineered scaffolds combined with stem cell therapies utilizing animal models. .
  • 18 June 2025: Homogeneously crosslinked in situ hydrogel enclosing high-density human-cancer cells promotes vascularized in vivo tumor modeling for immunecell therapy. Global Conference on Innovative Materials 2025 (15/06/2025-19/06/2025, Jeju Island, Korea).
  • 18 April 2025: A high-density dental stem cell therapy based on scaffold-free tissue engineering & regenerative medicine in dentistry. .
  • 29 December 2024: High-density stem cell-laden 3D microgels for tissue-integrative in situ transplantation therapy. .
  • 26 November 2024: High-density mesenchymal stem cells-laden rapidly degradable core/shell microgels for cartilage tissue regeneration. .
  • 22 November 2024: High-density stem cell-laden 3D microgels for tissue-integrative in situ transplantation therapy. .
  • 23 August 2024: Chitosan-based injectable hydrogels with high-density dental stem cells for therapeutic application in tissue engineering. .
  • 22 August 2024: Chitosan-based injectable hydrogels with high-density dental stem cells for therapeutic application in tissue engineering. The 34th Annual International Conference of the Korean Society for Chitin and Chitosan (KSCC) 2024 (22/08/2024-22/08/2024).
  • 31 May 2024: Immediately injectable dental stem cells-laden chitosan/hyaluronic acid hydrogel for vascularized bone tissue regeneration. The 12th World Biomaterials Congress (26/05/2024-31/05/2024, Daegu, South Korea).
  • 30 May 2024: Chitosan/oxidized hyaluronic acid based injectable hydrogel for craniofacial tissue regeneration in Dentistry. The 3rd International Conference on Recent Advances in Musculoskeletal Tissue Regeneration (30/05/2024-30/05/2024).
  • 06 June 2023: Immediately implantable high-density stem cells-laden microgel carrier for damaged tissue reconstruction. GCIM2023 (06/06/2023-09/06/2023, Jeju).
  • 28 March 2023: Immediately implantable graphene oxide-laden glycol chitosan / hyaluronic acid based hydrogels for in situ bone therapy. TERMIS-EU 2023 (28/03/2023-31/03/2023, Manchester).

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HKU Committee Appointments
  • 24 August 2022-Present: Faculty of Dentistry, Board of the. The teachers who are members of the Faculty and who are full-time employees of the University

Note

  • All publication and awards data are automatically fetched periodically from the HKU Scholars Hub.