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殷笑雪

Dr Yin, Iris Xiaoxue

BDS (Anhui Med); PhD (HK)

Dr Yin, Iris Xiaoxue 殷笑雪 - HKU Faculty of Dentistry 香港大學牙醫學院

Profile

Title
  • Research Assistant Professor
    助理教授（研究）
Division
Restorative Dental Sciences
E-mail
irisxyin@hku.hk
Biography
Dr. Iris Yin is research assistant professor in the Faculty of Dentistry at the University of Hong Kong. Dr. Yin specializes in the field of developing and evaluating biomaterials for minimum intervention in caries management. She has published 47 articles in international peer-reviewed journals, and one of her articles was awarded the WILEY Top Cited Article for 2020-2021. Dr. Yin is the primary investigator for a grant from the Health and Medical Research Fund, as well as a co-investigator for two grants from RGC General Research Fund and HKU Seed Fund for Basic Research. She is included in Stanford’s List of World’s Top 2% Scientists in 2023 and 2024.
Areas of Research Expertise
  • Caries management
  • Minimal invasive dentistry
  • Nanomaterials
Research Profile
Publication & Awards
Publications

    Article

  • Zhang Olivia Lili, Yin Iris Xiaoxue, Yu Ollie Yiru, Luk Kenneth, Niu John Yun, Chu Chun Hung. Advanced Lasers and Their Applications in Dentistry, Dentistry Journal 2025; 13(1) doi:10.3390/dj13010037
  • Xu Veena Wenqing, Nizami Mohammed Zahedul Islam, Yin Iris Xiaoxue, Niu John Yun, Yu Ollie Yiru, Chu Chun-Hung. Copper Materials for Caries Management: A Scoping Review, Journal of Functional Biomaterials 2024; 15(1) doi:10.3390/jfb15010010
  • Xu Grace Y., Zhao Irene S., Lung Christie Y.K., Yin Iris X., Lo Edward C.M., Chu Chun Hung. Silver Compounds for Caries Management, International Dental Journal 2024; 74(2): 179-186 doi:10.1016/j.identj.2023.10.013
  • Xu Grace Yuchan, Zhao Irene Shuping, Lung Christie Ying Kei, Yin Iris Xiaoxue, Lo Edward Chin Man, Chu Chun Hung. Frontiers of Global Research Trend on Root Caries: A Bibliometric Analysis, International Dental Journal 2024; doi:10.1016/j.identj.2024.06.007
  • Xu Veena Wenqing, Yin Iris Xiaoxue, Niu John Yun, Yu Ollie Yiru, Nizami Mohammed Zahedul Islam, Chu Chun Hung. Developing a novel antibacterial copper tetraamine fluoride, Journal of Dentistry 2024; 150: article no. 105320-article no. 105320 doi:10.1016/j.jdent.2024.105320
  • Xu Veena Wenqing, Nizami Mohammed Zahedul Islam, Yin Iris Xiaoxue, Niu John Yun, Yu Ollie Yiru, Chu Chun Hung. Research Interest in Copper Materials for Caries Management: A Bibliometric Analysis, Journal of Functional Biomaterials 2024; 15(9) doi:10.3390/jfb15090274
  • Chen Jieyi, Zhang Yuqing, Yin Iris Xiaoxue, Yu Ollie Yiru, Chan Alice Kit Ying, Chu Chun Hung. Preventing Dental Caries with Calcium-Based Materials: A Concise Review, Inorganics 2024; 12(9) doi:10.3390/inorganics12090253
  • Yin Iris Xiaoxue, Xu Veena Wenqing, Xu Grace Yuchan, Yu Ollie Yiru, Niu John Yun, Chu Chun Hung. Synthesis and Application of Silver Nanoparticles for Caries Management: A Review, Pharmaceuticals 2024; 17(10) doi:10.3390/ph17101264
  • Xu Veena Wenqing, Yin Iris Xiaoxue, Niu John Yun, Yu Ollie Yiru, Nizami Mohammed Zahedul Islam, Chu Chun Hung. The anti-caries effects of copper tetraamine fluoride on enamel: An in vitro study, Journal of Dentistry 2024; 151 doi:10.1016/j.jdent.2024.105446
  • Xu Veena Wenqing, Yin Iris Xiaoxue, Niu John Yun, Yu Ollie Yiru, Nizami Mohammed Zahedul Islam, Chu Chun Hung. Antibacterial and mineralising properties of copper tetraamine fluoride on dentine caries: A laboratory study, Journal of Dentistry 2024; 151 doi:10.1016/j.jdent.2024.105444
  • Yin Iris Xiaoxue, Niu John Yun, Mei May Lei, Tang Jinyao, Wu William Ka Kei, Chu Chun Hung. Tooth-Binding Graphene Quantum Dots Silver Nanocomposites for Prevention of Dental Caries, International Journal of Nanomedicine 2024; 19: 11195-11212 doi:10.2147/IJN.S486827
  • Xu Veena Wenqing, Yin Iris Xiaoxue, Niu John Yun, Yu Ollie Yiru, Nizami Mohammed Zahedul Islam, Chu Chun Hung. Antimicrobial properties of copper tetraamine fluoride, Journal of Applied Biomaterials & Functional Materials 2024; 22 doi:10.1177/22808000241307803
  • Zhang OL, Niu JY, Yin IX, Yu OY, Mei ML, Chu CH. Bioactive Materials for Caries Management: A Literature Review, Dentistry Journal 2023; 11(3) doi:10.3390/dj11030059
  • Zhang Lili, Niu Yun, Yin Xiaoxue Iris, Yu Yiru Ollie, Mei L May, Chu Chun Hung. Antibacterial Properties of the Antimicrobial Peptide Gallic Acid-Polyphemusin I (GAPI), Antibiotics 2023; 12(9) doi:10.3390/antibiotics12091350
  • Zhang Lili, Niu Yun, Yu Yiru Ollie, Yin Xiaoxue Iris, Mei L May, Chu Hung Chun. The Anti-Caries Effects of a Novel Peptide on Dentine Caries: An In Vitro Study, International Journal of Molecular Sciences 2023; 24(18) doi:10.3390/ijms241814076
  • Yan Iliana Gehui, Zheng Faith Miaomiao, Yin Iris Xiaoxue, Sun Ivy Guofang, Lo Edward Chin Man, Chu Chun Hung. Stability of Silver and Fluoride Contents in Silver Diamine Fluoride Solutions, International Dental Journal 2023; 73(6): 840-846 doi:10.1016/j.identj.2023.05.001
  • Niu JY, Yin X, Wu WKK, Li QL, Mei L, Chu CH. Efficacy of the dual-action GA-KR12 peptide for remineralising initial enamel caries: an in vitro study, Clinical Oral Investigations 2022; 26(3): 2441-2451 doi:10.1007/s00784-021-04210-1
  • XU W, Yin X, Niu Y, Luk K, Lo ECM, Chu CH. Power Output of Two Semiconductor Lasers: An Observational Study, Photonics 2022; 9(4): 219-219 doi:10.3390/photonics9040219
  • XU W, Yin X, Niu Y, Chan A, Lo ECM, Chu CH. Combined Effects of Topical Fluorides and Semiconductor Lasers on Prevention of Enamel Caries: A Systematic Review and Meta-Analysis, Photobiomodulation, Photomedicine, and Laser Surgery 2022; 40(6): 378-386 doi:10.1089/photob.2021.0184
  • Xue VW, Yin IX, Niu JY, Lo ECM, Chu CH, Zhao IS. Effects of a 445 nm diode laser and silver diamine fluoride in preventing enamel demineralisation and inhibiting cariogenic bacteria, Journal of Dentistry 2022; 126: article no. 104309-article no. 104309 doi:10.1016/j.jdent.2022.104309
  • Zhang Olivia Lili, Niu John Yun, Yin Iris Xiaoxue, Yu Ollie Yiru, Mei May Lei, Chu Chun Hung. Growing Global Research Interest in Antimicrobial Peptides for Caries Management: A Bibliometric Analysis, Journal of Functional Biomaterials 2022; 13(4): article no. 210-article no. 210 doi:10.3390/jfb13040210
  • Xu Veena Wenqing, Nizami Mohammed Zahedul Islam, Yin Iris Xiaoxue, Lung Christie Ying Kei, Yu Ollie Yiru, Chu Chun Hung. Caries Management with Non-Metallic Nanomaterials: A Systematic Review, International Journal of Nanomedicine 2022; 17: 5809-5824 doi:10.2147/IJN.S389038
  • Nizami Mohammed Zahedul Islam, Yeung Conson, Yin Iris Xiaoxue, Wong Amy Wai Yee, Chu Chun Hung, Yu Ollie Yiru. Tunnel Restoration: A Minimally Invasive Dentistry Practice, Clinical, Cosmetic and Investigational Dentistry 2022; 14: 207-216 doi:10.2147/CCIDE.S372165
  • Chawhuaveang Darren Dhananthat, Yu Ollie Yiru, Yin Iris Xiaoxue, Lam Walter Yu Hang, Chu Chun Hung. Topical Agents for Nonrestorative Management of Dental Erosion: A Narrative Review, Healthcare (Switzerland) 2022; 10(8): article no. 1413-article no. 1413 doi:10.3390/healthcare10081413
  • Nizami Mohammed Zahedul Islam, Yin Iris Xiaoxue, Lung Christie Ying Kei, Niu John Yun, Mei May Lei, Chu Chun Hung. In Vitro Studies of Graphene for Management of Dental Caries and Periodontal Disease: A Concise Review, Pharmaceutics 2022; 14(10): article no. 1997-article no. 1997 doi:10.3390/pharmaceutics14101997
  • Nizami Mohammed Zahedul Islam, Xu Veena Wenqing, Yin Iris Xiaoxue, Lung Christie Ying Kei, Niu John Yun, Chu Chun Hung. Ceramic Nanomaterials in Caries Prevention: A Narrative Review, Nanomaterials 2022; 12(24): article no. 4416-article no. 4416 doi:10.3390/nano12244416
  • Niu JY, Yin IX, Wu WKK, Li QL, Mei ML, Chu CH. Antimicrobial peptides for the prevention and treatment of dental caries: A concise review, Archives of Oral Biology 2021; 122: article no. 105022-article no. 105022 doi:10.1016/j.archoralbio.2020.105022
  • Chawhuaveang DD, Yu OY, Yin IX, Lam WYH, Mei ML, Chu CH. Acquired salivary pellicle and oral diseases: A literature review, Journal of Dental Sciences 2021; 16(1): 523-529 doi:10.1016/j.jds.2020.10.007
  • Niu JY, Yin IX, Mei ML, Wu WKK, Li QL, Chu CH. The multifaceted roles of antimicrobial peptides in oral diseases, Molecular Oral Microbiology 2021; 36(3): 159-171 doi:10.1111/omi.12333
  • Zhao IS, Xue VW, Yin IX, Niu JY, Lo ECM, Chu CH. Use of a novel 9.3-μm carbon dioxide laser and silver diamine fluoride: Prevention of enamel demineralisation and inhibition of cariogenic bacteria, Dental Materials 2021; 37(6): 940-948 doi:10.1016/j.dental.2021.02.017
  • Zhang J, Got SR, Yin X, Lo ECM, Chu CH. A Concise Review of Silver Diamine Fluoride on Oral Biofilm, Applied Sciences 2021; 11(7): article no. 3232-article no. 3232 doi:10.3390/app11073232
  • Lung CYK, Abdalla MM, Chu CH, Yin I, Got SR, Matinlinna JP. A Multi-Element-Doped Porous Bioactive Glass Coating for Implant Applications, Materials 2021; 14(4): article no. 961-article no. 961 doi:10.3390/ma14040961
  • Luk K, Zhao IS, Yin IX, Niu JY, Gutknecht N, Chu CH. Irradiation methods of 10,600 nm carbon dioxide laser for dental caries prevention, Lasers in Dental Science 2021; 5(1): 1-8 doi:10.1007/s41547-021-00114-1
  • XUE VW, Zhao IS, Yin IX, Niu JY, Lo ECM, Chu CH. Effects of 9,300 nm Carbon Dioxide Laser on Dental Hard Tissue: A Concise Review, Clinical, Cosmetic and Investigational Dentistry 2021; 13: 155-161 doi:10.2147/CCIDE.S304273
  • XUE VW, Zhao IS, Yin IX, Niu JY, Lo ECM, Chu CH. Effects of Treatment Combining 9300 nm Carbon Dioxide Lasers and Fluoride on Prevention of Enamel Caries: A Systematic Review and Meta-Analysis, Applied Sciences 2021; 11(9): article no. 3996-article no. 3996 doi:10.3390/app11093996
  • Niu JY, Yin IX, Wu WKK, Li QL, Mei ML, Chu CH. A novel dual-action antimicrobial peptide for caries management, Journal of Dentistry 2021; 111: article no. 103729-article no. 103729 doi:10.1016/j.jdent.2021.103729
  • Niu JY, Yin IX, Wu WKK, Li QL, Mei ML, Chu CH. Remineralising dentine caries using an artificial antimicrobial peptide: An in vitro study, Journal of Dentistry 2021; 111: article no. 103736-article no. 103736 doi:10.1016/j.jdent.2021.103736
  • Nizami Mohammed Zahedul Islam, Xu Veena W., Yin Iris X., Yu Ollie Y., Chu Chun Hung. Metal and metal oxide nanoparticles in caries prevention: A review, Nanomaterials 2021; 11(12): article no. 3446-article no. 3446 doi:10.3390/nano11123446
  • Yin IX, Zhao IS, Mei ML, Lo ECM, Tang J, Li Q, So LY, Chu CH. Synthesis and Characterization of Fluoridated Silver Nanoparticles and Their Potential as a Non-Staining Anti-Caries Agent, International Journal of Nanomedicine 2020; 15: 3207-3215 doi:10.2147/IJN.S243202
  • Zhao IS, Yin IX, Mei ML, Lo ECM, Tang J, Li Q, So LY, Chu CH. Remineralising Dentine Caries Using Sodium Fluoride with Silver Nanoparticles: An In Vitro Study, International Journal of Nanomedicine 2020; 15: 2829-2839 doi:10.2147/IJN.S247550
  • Yin IX, Zhao IS, Mei ML, Li Q, Yu OY, Chu CH. Use of silver nanomaterials for caries prevention: A concise review, International Journal of Nanomedicine 2020; 15: 3181-3191 doi:10.2147/IJN.S253833
  • Yin IX, Zhang J, Zhao IS, Mei ML, Li Q, Chu CH. The antibacterial mechanism of silver nanoparticles and its application in dentistry, International Journal of Nanomedicine 2020; 15: 2555-2562 doi:10.2147/IJN.S246764
  • Yin IX, Yu OY, Zhao IS, Mei ML, Li QL, Tang J, Lo ECM, Chu CH. Inhibition of dentine caries using fluoride solution with silver nanoparticles: An in vitro study, Journal of Dentistry 2020; 103: article no. 103512-article no. 103512 doi:10.1016/j.jdent.2020.103512
  • Yin X, Yu OY, Zhao IS, Mei ML, Li QL, Tang J, Chu CH. Developing biocompatible silver nanoparticles using epigallocatechin gallate for dental use, Archives of Oral Biology 2019; 102: 106-112 doi:10.1016/j.archoralbio.2019.03.022

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    Conference Paper

  • Yan IG, Zheng FM, Yin IX, Sun IG, Lo ECM, Chu CH. Stability of Silver and Fluoride Contents in Silver Diamine Fluoride Solutions, The 44th Asia Pacific Dental Congress 2023 (44th APDC 2023) & The 12th Hong Kong International Dental Expo and Symposium (12th HKIDEAS) (09/06/2023-11/06/2023, Hong Kong) 2023;
  • Yan IG, Zheng FM, Yin IX, Sun IG, Lo ECM, Chu CH. Knowledge, Comparison of Lesions Colour Changes in Different Application Time With 38% Silver Diamine Fluoride, 15th International Conference of the Asian Academy of Preventive Dentistry (AAPD) 2023 (08/11/2023-11/11/2023, Hong Kong) 2023;

    • PG Thesis

  • Yin Iris Xiaoxue Use of silver nanoparticles with sodium fluoride on caries prevention[PG Thesis]. Pokfulam, Hong Kong: The University of Hong Kong; 2020.
Honours & Awards
  • 2022. Chu CH, Mei L, Niu Y, Yin XI. WILEY Top Cited Article 2020-2021 Award: WILEY Top Cited Article 2020-2021 Award for the mostly cited article published in Molecular Oral Microbiology.
Knowledge Exchange
  • 31 August 2024: Zheng Miaomiao Faith, Yeung Conson, Yu Ka Fung, Yin Xiaoxue, Luo Weijia, Zhang Lili, Chu Chun Hung, Chai Haotian Hollis, Loo Tsutao Henry, Chau Yik Tung Natalie , Nicholas Chin , Huang Wai Sum Jacky , Kwan Wing Hei Kelly , Kwok Ching Long Edison , Lee Long Ting Marco , Yuan Kun Lin Joseph , Aliyah Sat , Idris Sat , Edison Chiang . Mobile Dental Care5.
  • 01 July 2022: Wong Amy Wai Yee, Chu Chun Hung, Duangthip Duangporn, Yeung Conson, Yin Xiaoxue, Yu Yiru Ollie, Lam Yu Hang Walter, Leung Katherine Chiu Man. Faculty Knowledge Exchange Award 2022 (Faculty of Dentistry) for 'Promoting Oral Health of Non-institutionalised Older Adults with A Non-governmental Organisation in Hong Kong'.
  • 01 July 2021: Duangthip Duangporn, Chu Chun Hung, Lo Edward Chin Man, Yiu Cynthia Kar Yung, Gao Shiqian, Yeung Conson, Fong Zhan Yan, Jiang Meng, Sung Chia-Chia Monica, Tan Mabel Hui Min, Yan Gehui Iliana, Yin Xiaoxue. Faculty Knowledge Exchange Award 2021 (Faculty of Dentistry) for ‘Promoting Child Oral Health and Managing Tooth Decay in Preschool Children’.
  • 01 July 2021: Duangthip Duangporn, Chu Chun Hung, Yeung Conson, Gao Shiqian, Fong Zhan Yan, Jiang Meng Chloe, Sung Chia-Chia Monica, Tan Mabel Hui Min, Yan Gehui, Yin Xiaoxue, Lo Edward Chin Man, Yiu Cynthia Kar Yung. Faculty Knowledge Exchange Award 2021 (Faculty of Dentistry) for ‘Promoting Child Oral Health and Managing Tooth Decay in Preschool Children’.
Grants
  • Project Title: Arresting dental caries with a novel silver complex fluoride
    Grant Type: General Research Fund (GRF) 2022/23
    Funding Year: 2022
    Amount: HK$1,150,713
    Principal Investigator: Professor Chu, Chun Hung
    Co-investigator(s): Professor Tang Jinyao, Dr Yin Xiaoxue Iris
  • Project Title: Developing a novel multi-functionalised graphene oxide nanocomposite for arresting dental caries
    Grant Type: Health and Medical Research Fund 2021
    Funding Year: 2022
    Amount: HK$1,200,000
    Principal Investigator: Dr Yin, Xiaoxue Iris
    Co-principal investigator(s): Professor Chu Chun Hung Co-investigator(s): Dr Nizami Mohammed Zahedul Islam, Nishina Yuta
HKU Committee Appointments
  • 20 November 2020-31 August 2022: Faculty of Dentistry, Board of the. Such other persons not being teachers as may be appointed to the Board by the Senate on the recommendation of the Board, provided that the number of such persons shall not exceed one-fourth of the whole number of members of the Board

Note

  • All publication and awards data are automatically fetched periodically from the HKU Scholars Hub.