Profile
- Clinical Assistant Professor
臨床助理教授
Paediatric Dentistry & Orthodontics
+852 2859 0451
Professor Zhiyi Shan holds the position of Clinical Assistant Professor in Orthodontics at the Faculty of Dentistry, The University of Hong Kong. She received her Bachelor of Dental Surgery (BDS) and Master of Dental Surgery (MDS) from Shanghai Jiao Tong University and her PhD Degree from HKU. Prof. Shan’s research interests centre on digital orthodontics, artificial intelligence in dentistry, and bioengineering in orthodontics. She has secured five external/internal grants as the principal investigator and contributed to the field through publications in high-impact journals as well as being an editorial board member/invited reviewer of over ten reputational journals. Recognized as a Fellow of the Royal College of Surgeons of Edinburgh in Orthodontics, Prof. Shan currently serves as Deputy Director of the Taught Postgraduate Programs in Orthodontics at the University of Hong Kong. Driven by a passion for innovation and education, Prof. Zhiyi Shan is committed to advancing orthodontic knowledge through her clinical practice, research, and teaching.
Craniofacial Regeneration
- Digital orthodontics
- Laser therapy in orthodontics
- Periodontal tissue regeneration
Article
- Liu Junqi, Yap Adrian Ujin, Li Kar Yan, Hung Kuo Feng, Ai Qi Yong H., Shan Zhiyi. Condylar bone regeneration following temporomandibular joint disc repositioning surgery: a systematic review and meta-analysis, BMC Oral Health 2026; 26(1)
- Ding Xiaoqian, Zhang Guanning, Yiu Cynthia Kar Yung, Li Xin, Shan Zhiyi. Unleashing the Potential of Tannic Acid in Dentistry: A Scoping Review of Applications, Bioengineering 2025; 12(5)
- Hao Jing, Nalley Andrew, Yeung Andy Wai Kan, Tanaka Ray, Ai Qi Yong H, Lam Walter Yu Hang, Shan Zhiyi, Leung Yiu Yan, AlHadidi Abeer, Bornstein Michael M, Tsoi James Kit Hon, McGrath Colman, Hung Kuo Feng. Characteristics, licensing, and ethical considerations of openly accessible oral-maxillofacial imaging datasets: a systematic review, npj Digital Medicine 2025; 8
- Liu Keyuan, Elbatel Marawan, Chu Guang, Shan Zhiyi, Sum Fung Hou Kumoi Mineaki Howard, Hung Kuo Feng, Zhang Chengfei, Li Xiaomeng, Yang Yanqi. FDTooth: Intraoral Photographs and CBCT Images for Fenestration and Dehiscence Detection, Scientific Data 2025; 12(1)
- Yung Augustine Ka Chun, Chan Ho Hin, Liu Junqi, Hung Kuo Feng, Tang Zhongyuan, Shan Zhiyi. Comparative Three Dimensional Evaluation of Skeletal and Dento-Alveolar Effects Between Tooth-Borne and Bone-Anchored Maxillary Expansion for Growing Patients—A Systematic Review and Meta-Analysis, Orthodontics & Craniofacial Research 2025;
- Sum Fung Hou Kumoi Mineaki Howard, Shan Zhiyi, Chan Yat Him Dave, Chu Ryan Julian Dick Hei, Pelekos George, She Tsang Tsang. Biomechanical Considerations in the Orthodontic Treatment of a Patient with Stabilised Stage IV Grade C Generalised Periodontitis: A Case Report, Bioengineering 2024; 11(4)
- Au Yeung King Sang Rita, Shan Zhiyi, Sum Fung Hou Kumoi Mineaki Howard, Wong Ka Wai Frank, Lee Hui Man Gillian, Yang Yanqi. Association between occlusal features and masticatory function in Hong Kong preschool children: a survey with one-year longitudinal follow-up, BMC Oral Health 2024; 24(1)
- Li Zhuoying, Hung Kuo Feng, Ai Qi Yong H, Gu Min, Su Yu-xiong, Shan Zhiyi. Radiographic Imaging for the Diagnosis and Treatment of Patients with Skeletal Class III Malocclusion, Diagnostics 2024; 14(5)
- Hao Jing, Wong Lun M., Shan Zhiyi, Ai Qi Yong H., Shi Xieqi, Tsoi James Kit Hon, Hung Kuo Feng. A Semi-Supervised Transformer-Based Deep Learning Framework for Automated Tooth Segmentation and Identification on Panoramic Radiographs, Diagnostics 2024; 14(17): article no. 1948-article no. 1948
- Zheng Jie, Ding Xiaoqian, Pu Jingya Jane, Chung Sze Man, Ai Qi Yong H., Hung Kuo Feng, Shan Zhiyi. Unlocking the Potentials of Large Language Models in Orthodontics: A Scoping Review, Bioengineering 2024; 11(11): article no. 1145-article no. 1145
- Hung Kuo Feng, Shan Zhiyi, Tse Irene OL, Leung Ho sang, Chen Yu, Liang Yannis Yan, King Ann D., Lam WK Jacky, Ai Qi Yong H.. Association of Cigarette Consumption and Mucosal Thickening in the Paranasal Sinuses on MRI
, International Dental Journal 2024;
- Shan ZY, Ren C, Gu M, Lin YF, Sum FHKMH, McGrath C, Jin LJ, Zhang CF, Yang YQ. Effects of Low-Level Laser Therapy on Dentin Hypersensitivity in Periodontally Compromised Patients Undergoing Orthodontic Treatment: A Randomised Controlled Trial, Journal of Clinical Medicine 2023; 12(4)
- Shan Z, Liao C, Lu J, Yeung CPW, Li KY, Gu M, Chu CH, Yang Y. Improvement of parents’ oral health knowledge by a school-based oral health promotion for parents of preschool children: a prospective observational study, BMC Oral Health 2023; 23(1)
- Liu Junqi, Zhang Chengfei, Shan Zhiyi. Application of Artificial Intelligence in Orthodontics: Current State and Future Perspectives, Healthcare 2023; 11(20)
- Mao Kaijing, Wong Lun M., Zhang Rongli, So Tiffany Y., Shan Zhiyi, Hung Kuo Feng, Ai Qi Yong H.. Radiomics Analysis in Characterization of Salivary Gland Tumors on MRI: A Systematic Review, Cancers 2023; 15(20): article no. 4918-article no. 4918
- Ho CY, Liao CS, Lu JJ, Shan ZY, Gu M, Bridges SM, Yang Y. 3‐Dimensional simulations and student learning in orthodontic education, European Journal of Dental Education 2022; 26(3): 435-445
- Huang L, Wang ZL, Shan Z, Yeung WKA, Yang Y, Liang ZG, Gu M. Nasal asymmetry changes during growth and development in 6‐ to 12‐year‐old children with repaired unilateral cleft lip and palate: A 3D computed tomography analysis, Journal of Anatomy 2022; 240(1): 155-165
- Wei Tingting, Shan Zhiyi, Wen Xin, Zhao Ning, Shen Gang. Dynamic alternations of RANKL/OPG ratio expressed by cementocytes in response to orthodontic-induced external apical root resorption in a rat model, Molecular Medicine Reports 2022; 26(1): article no. 228-article no. 228
- Shan Z, Hsung RTC, Zhang C, Ji J, Choi WS, Wang W, Yang Y, Gu M, Khambay BS. Anthropometric accuracy of three-dimensional average faces compared to conventional facial measurements, Scientific Reports 2021; 11: article no. 11254-article no. 11254
- Shan Z, Ji J, McGrath C, Gu M, Yang Y. Effects of low-level light therapy on dentin hypersensitivity: a systematic review and meta-analysis, Clinical Oral Investigations 2021; 25(12): 6571-6595
- Shan Z, WONG KWF, McGrath C, Gu M, Yang Y. Comprehensive Effects of Photobiomodulation Therapy as an Adjunct to Post-orthodontic Treatment Care: A Systematic Review, Oral Health and Preventive Dentistry 2021; 19(1): 203-216
- Gu M, Yang Y, Shan Z. The Association between Mastication, Malocclusion, and Craniofacial Morphology, International Journal of Dentistry and Oral Science 2018; 2018: 6-11
- Shan Zhiyi, Xu Ziqing, Shen Gang. Research progress on three-dimensional finite-element analysis method for lingual orthodontics, International Journal of Stomatology 2016; 43(5): 560-564
Show More
Conference Paper
- Shan Zhiyi. Comparing Effects of Bone-anchored and Tooth-anchored Maxillary Expanders on Adolescents, 2025 IADR/PER General Session & Exhibition (25/06/2025-28/06/2025, Barcelona) 2025;
- Liu Junqi, Shan Zhiyi. Effects of disc repositioning surgery on condylar bone regeneration, 2025 IADR/PER General Session & Exhibition (25/06/2025-28/06/2025, Barcelona) 2025;
- Zhang Guanning, Shan Zhiyi. PBM’s effects on plaque microbiome for periodontal-orthodontic patients during retention, 2025 International Association for Dental, Oral, and Craniofacial Research (IADR) (25/06/2025-28/06/2025, Barcelona) 2025;
- Li Zhuoying, Shan Zhiyi. Condylar High-dimensional Image Feature Analysis for Skeletal Class Ⅲ Malocclusion, 2025 International Association for Dental, Oral, and Craniofacial Research (IADR) (25/06/2025-28/06/2025, Barcelona) 2025;
- Ding Xiaoqian, Shan Zhiyi. Improving Wet Bonding Performance of Orthodontic Brackets with Tannic Acid, 2025 International Association for Dental, Oral, and Craniofacial Research (IADR) (25/06/2025-28/06/2025, Barcelona) 2025;
- Chan Kay Shuen, Shan Zhiyi. Association between Facial Profile and Dentoskeletal Changes in High-Angle Skeletal Class II Patients before and after Orthodontic Treatment: A Retrospective Cephalometric Study, 99th EUROPEAN ORTHODONTIC SOCIETY CONGRESS (09/06/2024-13/06/2024, Athens) 2024;
- Shan Z, Ren C, Gu M, Lin Y, Sum F, McGrath C, Jin L, Zhang C, Yang Y. Low-level Laser Therapy Improves Dentine Hypersensitivity in controlled periodontitis subjects, 2022 IADR/APR General Session & Exhibition 2022;
- Shan Z, Hsung TC, Choi WWS, Yang Y, Khambay BS, Gu M. Anthropometric accuracy of three-dimensional average faces compared to conventional facial measurements, 2021 IADR/AADR/CADR General Session 2021;
Show More
- 2025. Shan Z. Silver Award for Exemplary Teaching and Learning: eLearning Forum Asia 2025 (14/08/2025-15/08/2025, Bangkok).
- 2025. Shan Z. 2025 Growth and Development Research Award: 2025 IADR/PER General Session & Exhibition (25/06/2025-28/06/2025, Barcelona).
- 2022. Shan Z. CTOR Award Finalist for Student Excellence in Orthodontic Research: 2022 IADR/APR General Session & Exhibition.
- 2021. Shan Z. CTOR Award for Student Excellence in Orthodontics Research: 2021 IADR General Session.
- 22 August 2025: Shan Zhiyi. Developing customized labial orthodontic fixed appliance.
- 01 August 2025: Shan Zhiyi. What to know about PBM in orthodontic treatment?.
- 04 July 2025: Shan Zhiyi. An Overview of Interproximal Enamel Reduction in orthodontics.
- 10 June 2025: Shan Zhiyi. Advances in Diagnosis and Treatment of Skeletal Class III Malocclusion.
- 04 March 2025: Shan Zhiyi. Pioneering Orthodontic Education: An Overview of HKU’s Taught Postgraduate (TPG) .
- 02 January 2025: Shan Zhiyi. Developing an AI-assisted orthodontic diagnosis and treatment planning system.
- 04 December 2024: Shan Zhiyi. Transition from primary to permanent dentition.
- 16 October 2024: Shan Zhiyi. Leveraging Artificial Intelligence to Transform Orthodontics.
- 23 September 2024: Shan Zhiyi, Lam Pui Ying Phoebe, Qiao Wei Will, Hung Kuo Feng, McDonald Tom, Wong Siu Him Janus. 2024/25 KE Strategic Impact Funding: KE-SI-2024/25-15: Empowering Secondary School Students' Oral Health: Harnessing the Power of 3D Simulations and AI Integration ($392,720).
- 23 September 2024: Shan Zhiyi. The need for early orthodontic check-up for children with anterior crossbite.
- 16 September 2022: Shan Zhiyi. Cephalometric analysis in the DMFR MOOC.
- 16 September 2022: Shan Zhiyi. CBCT and ectopic impacted canine.
Show More
- Project Title: Development of an interpretable prediction tool for orthodontically-induced external root resorption using high-dimensional image features and risk factors
Grant Type: General Research Fund (GRF) 2025/26
Funding Year: 2025
Amount: HK$782,286
Principal Investigator: Professor Hung, Kuo Feng
Co-investigator(s): Dr Ai Qiyong Hemis, Professor Shan Zhiyi, Professor Bornstein Michael
- Project Title: Deciphering the Effects of Photobiomodulation Therapy (PBM) on Periodontitis Using a Micro-Physiological System
Grant Type: General Research Fund (GRF) 2025/26
Funding Year: 2025
Amount: HK$1,152,917
Principal Investigator: Professor Shan, Zhiyi
Co-investigator(s): Professor Yang Weifa, Professor Zhang Chengfei, Professor Yang Yanqi
- Project Title: Development and validation of an AI-assisted orthodontic screening tool for circumpubertal adolescents through 3D average face database construction
Grant Type: General Research Fund (GRF) 2024/25
Funding Year: 2024
Amount: HK$955,568
Principal Investigator: Professor Shan, Zhiyi
Co-investigator(s): Professor Yu Lequan, Professor Yiu Cynthia Kar Yung, Professor Hung Kuo Feng, Professor McGrath Colman, Dr Liu Pei
- Project Title: Development and validation of a periodontium-on-a-chip system for periodontitis
Grant Type: Seed Fund for PI Research – Basic Research
Funding Year: 2023
Amount: HK$46,520
Principal Investigator: Professor Shan, Zhiyi
Co-investigator(s): Professor Zhang Chengfei
- Project Title: Developing an Automated Digital Workflow for Asymmetry Assessment and Correction in Computer-Assisted Orthognathic Surgery: A Prospective Clinical Study
Grant Type: Health and Medical Research Fund 2023
Funding Year: 2023
Amount: HK$560,780
Principal Investigator: Professor Yang, Weifa
Co-investigator(s): Professor Su Yuxiong, Professor Peng Yifan Evan, Professor Yu Lequan, Professor Shan Zhiyi, Professor Leung Mike Yiu Yan
- Project Title: Effects of photobiomodulation therapy on orthodontically-induced inflammatory root resorption in patients undergoing fixed-appliance orthodontic treatment
Grant Type: Seed Fund for Basic Research for New Staff
Funding Year: 2022
Amount: HK$150,000
Principal Investigator: Professor Shan, Zhiyi
Co-investigator(s): Professor Yang Yanqi
- Project Title: 2025 IADR/PER General Session & Exhibition
Grant Type: Conference Support for Teaching Staff
Funding Year: 0
Amount: HK$18,000
Principal Investigator: Professor Shan, Zhiyi
Show More
- 04 July 2025: An Overview of Interproximal Enamel Reduction in orthodontics. .
- 20 October 2024: Leveraging AI to Transform Orthodontics. 2024 TU-HKU-FJMU International Symposium on Oral Health Science (18/10/2024-20/10/2024, Sendai).
- : Pioneering Orthodontic Education: An Overview of HKU’s Taught Postgraduate (TPG) . 2025 South China Expo.
- : Advances in Diagnosis and Treatment of Skeletal Class III Malocclusion. 2025 HKU Global Campus.
- : An Overview of Interproximal Enamel Reduction in orthodontics, dilemmas and challenge. 2025 Pierre Fauchard Academy.
- 01 June 2023-Present: Discontinuation, Committee on. 1 member from each Faculty (Dentistry) from a panel of three in order of precedence for a period of 2 years, renewable up to a maximum of 4 consecutive years
- 01 September 2022-Present: Faculty of Dentistry, Board of the. The teachers who are members of the Faculty and who are full-time employees of the University
- All publication and awards data are automatically fetched periodically from the .
