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楊解綱

Professor Yang, Daniel Jiegang

BDS (WHU); MDS (WHU); PhD (WHU)

Professor Yang, Daniel Jiegang 楊解綱 - HKU Faculty of Dentistry 香港大學牙醫學院

Profile

Title
  • Clinical Assistant Professor in Oral and Maxillofacial Surgery
    口腔頜面外科臨床助理教授
Division
Oral and Maxillofacial Surgery
E-mail
yangjg@hku.hk
Phone
+852 2859 0266
Research Theme
Oral Cancer
Areas of Research Expertise
  • Cleft lip and palate
  • Maxillofacial deformity
  • Immunotherapy
Research Profile
Publication & Awards
Publications

    Article

  • Yang Jiegang, Tang Zhongyuan, Shan Zhiyi, Leung Yiu Yan. Maxillary Deficiency: Treatments and Applications for Adolescents, Applied Sciences 2025; 15(6) doi:10.3390/app15063256
  • Zhang Lin-Zhou, Yang Jie-Gang, Chen Gai-Li, Xie Qi-Hui, Fu Qiu-Yun, Xia Hou-Fu, Li Yi-Cun, Huang Jue, Li Ye, Wu Min, Liu Hai-Ming, Wang Fu-Bing, Yi Ke-Zhen, Jiang Huan-Gang, Zhou Fu-Xiang, Wang Wei, Yu Zi-Li, Zhang Wei, Zhong Ya-Hua, Bian Zhuan, Yang Hong-Yu, Liu Bing, Chen Gang. PD-1/CD80+ small extracellular vesicles from immunocytes induce cold tumours featured with enhanced adaptive immunosuppression, Nature Communications 2024; 15(1): 1-18 doi:10.1038/s41467-024-48200-9
  • Lai Wen Qiang, Xia Hou Fu, Chen Gao Hong, Wang Xiao Le, Yang Jie Gang, Wu Lian Zhi, Zhao Yi Fang, Jia Yu Lin, Chen Gang. p-AKT/VPS4B regulates the small extracellular vesicle size in venous malformation endothelial cells, Oral Diseases 2024; 30(3): 1273-1285 doi:10.1111/odi.14608
  • Qin Chuanqi, Li Jian, Yang Jiegang, Cheng Yibin, Fu Xiazhou. Soft Palate Dysplasia: Properties and Surgical Techniques, Plastic and Reconstructive Surgery 2024; 153(6): 1368-1377 doi:10.1097/PRS.0000000000010787
  • Dong Zhe, Yang Jiegang, Fu Yuchuan, Li Jian. Comprehensive three-dimensional cone beam computed tomography assessment unilateral alveolar cleft reconstruction using autologous iliac cancellous bone combined with deproteinized bovine bone: A clinical retrospective evaluation, Journal of Cranio-Maxillofacial Surgery 2024; doi:10.1016/j.jcms.2024.06.002
  • Xie Ying, Dong Zhe, Yang Jiegang, Fu Yuchuan, Qin Chuanqi, Li Jian. Application of modified Mulliken method in correction of secondary bilateral cleft lip nasolabial deformity, Chinese Journal of Medical Aesthetics and Cosmetology 2024; 30(2): 126-130 doi:10.3760/cma.j.issn.1671-0290.2024.02.008
  • Qin Chuanqi, Li Jian, Yang Jiegang, Wang Yuting, Fu Yuchuan, Fu Xiazhou. A new perspective: Quantitative description of the Cupid's peak aesthetics essence, Journal of Plastic, Reconstructive and Aesthetic Surgery 2024; 99: 577-583 doi:10.1016/j.bjps.2024.10.022
  • Zhang Yuying, Dai Jiawei, Fu Xiazhou, Yang Jiegang, Fu Yuchuan, Li Jian. Real-Time Image-Guided Navigation in the Management of Alveolar Cleft Repair, Cleft Palate-Craniofacial Journal 2023; 60(2): 225-232 doi:10.1177/10556656211057744
  • Xie Qi Hui, Wang Wei Ming, Yang Jie Gang, Xia Hou Fu, Xiao Bo Lin, Chen Gao Hong, Huang Jue, Li Rui Fang, Chen Gang. ALIX promotes cell migration and invasion of head and neck squamous cell carcinoma by regulating the expression of MMP9, MMP14, VEGF-C, Archives of Oral Biology 2023; 151: article no. 105696-article no. 105696 doi:10.1016/j.archoralbio.2023.105696
  • Yang Jiegang, Li Jian, Qin Chuanqi, Fu Xiazhou. A WAP-Based Concept Acquisition Teaching Model in Cleft Lip and Palate Phenotype and Embryonic Development: Functionality and Usability Study, Cleft Palate Craniofacial Journal 2023; doi:10.1177/10556656231174433
  • Zhang L. Z., Yang J. G., Xia H. F., Huang J., Liu H. M., Wu M., Liu B., Wang W. M., Chen G.. PD-1 Carried on Small Extracellular Vesicles Leads to OSCC Metastasis, Journal of Dental Research 2023; 102(7): 795-805 doi:10.1177/00220345231165209
  • Huang Jue, Yang Jie Gang, Ren Jian Gang, Xia Hou Fu, Chen Gao Hong, Fu Qiu Yun, Zhang Lin Zhou, Liu Hai Ming, Wang Kui Ming, Xie Qi Hui, Chen Gang. Overexpression of RAB27A in Oral Squamous Cell Carcinoma Promotes Tumor Migration and Invasion via Modulation of EGFR Membrane Stability, International Journal of Molecular Sciences 2023; 24(17): article no. 13103-article no. 13103 doi:10.3390/ijms241713103
  • Wu Zhaoyi, Yue Haitang, Li Jian, Yang Jiegang, Bian Zhuan, He Miao. Two novel and de novo KMT2D mutations on the same allele cause Kabuki syndrome, Chinese Journal of Stomatology 2023; 58(8): 809-814 doi:10.3760/cma.j.cn112144-20230324-00112
  • Zhang Wei, Yang Jiegang, Wang Beike, Lu Youtao, Yang Jingbo, Zhong Wenqun, Yu Ziyan, Qin Zhiyuan, Xiao Bolin, Wang Kuiming, Ma Yi Y., Amaravadi Ravi, Herlyn Meenhard, Kim Junhyong, Xu Xiaowei, Guo Wei. HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation, Cell Reports 2023; 42(11): article no. 113352-article no. 113352 doi:10.1016/j.celrep.2023.113352
  • Zhang Wei, Zhong Wenqun, Wang Beike, Yang Jiegang, Yang Jingbo, Yu Ziyan, Qin Zhiyuan, Shi Alex, Xu Wei, Zheng Cathy, Schuchter Lynn M., Karakousis Giorgos C., Mitchell Tara C., Amaravadi Ravi, Herlyn Meenhard, Dong Haidong, Gimotty Phyllis A., Daaboul George, Xu Xiaowei, Guo Wei. ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression, Developmental Cell 2022; 57(3): 329-343.e7 doi:10.1016/j.devcel.2022.01.002
  • Chen Gao Hong, Yang Jie Gang, Xia Hou Fu, Zhang Lin Zhou, Chen Yin Hsueh, Wang Kui Ming, Duan Xu, Wu Lian Zhi, Zhao Yi Fang, Chen Gang. Endothelial cells induce degradation of ECM through enhanced secretion of MMP14 carried on extracellular vesicles in venous malformation, Cell and Tissue Research 2022; 389(3): 517-530 doi:10.1007/s00441-022-03657-2
  • Kuhn Madeline, Zhang Yang, Favate John, Morita Mayu, Blucher Aurora, Das Sukanya, Liang Shun, Preet Ranjan, Parham Louis R., Williams Kathy N., Molugu Sudheer, Armstrong Randall J., Zhang Wei, Yang Jiegang, Hamilton Kathryn E., Dixon Dan A., Mills Gordon, Morgan Terry K., Shah Premal, Andres Sarah F.. IMP1/IGF2BP1 in human colorectal cancer extracellular vesicles, American Journal of Physiology - Gastrointestinal and Liver Physiology 2022; 323(6): G571-G585 doi:10.1152/ajpgi.00121.2022
  • Wang Bei Ke, Li Hui Min, Yang Jie Gang, Ren Jian Gang, Cai Yu, Zhao Ji Hong, Zhao Yi Fang, Jia Jun, Zhang Wei. Surviving Inhibition Induces Cell Cycle Arrest and Disrupts Multipotency in Haemangioma Stem Cells, The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA) 2021; 24(1): 21-31 doi:10.3290/j.cjdr.b1105869
  • Yang Jie Gang, Wang Wei Ming, Xia Hou Fu, Yu Zi Li, Li Hui Min, Ren Jian Gang, Chen Gang, Wang Bei Ke, Jia Jun, Zhang Wei, Zhao Yi Fang. Lymphotoxin-α promotes tumor angiogenesis in HNSCC by modulating glycolysis in a PFKFB3-dependent manner, International Journal of Cancer 2019; 145(5): 1358-1370 doi:10.1002/ijc.32221
  • Chen Gang, Huang Alexander C., Zhang Wei, Zhang Gao, Wu Min, Xu Wei, Yu Zili, Yang Jiegang, Wang Beike, Sun Honghong, Xia Houfu, Man Qiwen, Zhong Wenqun, Antelo Leonardo F., Wu Bin, Xiong Xuepeng, Liu Xiaoming, Guan Lei, Li Ting, Liu Shujing, Yang Ruifeng, Lu Youtao, Dong Liyun, McGettigan Suzanne, Somasundaram Rajasekharan, Radhakrishnan Ravi, Mills Gordon, Lu Yiling, Kim Junhyong, Chen Youhai H., Dong Haidong, Zhao Yifang, Karakousis Giorgos C., Mitchell Tara C., Schuchter Lynn M., Herlyn Meenhard, Wherry E. John, Xu Xiaowei, Guo Wei. Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response, Nature 2018; 560(7718): 382-386 doi:10.1038/s41586-018-0392-8
  • Zhong Wen Qun, Zhang Wei, Gao Lu, Chen Gang, Sa Guo Liang, Yang Jie Gang, Zhao Yi Fang, Sun Yan Fang. Activated autophagy contributes to the development of lymphatic malformations, International Journal of Clinical and Experimental Pathology 2017; 10(5): 5117-5128
  • Ren Jian gang, Xia Hou fu, Yang Jie gang, Zhu Jun yi, Zhang Wei, Chen Gang, Zhao Ji hong, Sun Yan fang, Zhao Yi fang. Down-regulation of polycystin in lymphatic malformations: possible role in the proliferation of lymphatic endothelial cells, Human Pathology 2017; 65: 231-238 doi:10.1016/j.humpath.2017.05.016
  • Yang Jie Gang, Sun Yan Fang, He Ke Fei, Ren Jian Gang, Liu Zhuo Jue, Liu Bing, Zhang Wei, Zhao Yi Fang. Lymphotoxins Promote the Progression of Human Lymphatic Malformation by Enhancing Lymphatic Endothelial Cell Proliferation, American Journal of Pathology 2017; 187(11): 2602-2615 doi:10.1016/j.ajpath.2017.07.019
  • Li Hui Min, Yang Jie Gang, Liu Zhuo Jue, Wang Wei Ming, Yu Zi Li, Ren Jian Gang, Chen Gang, Zhang Wei, Jia Jun. Blockage of glycolysis by targeting PFKFB3 suppresses tumor growth and metastasis in head and neck squamous cell carcinoma, Journal of Experimental and Clinical Cancer Research 2017; 36(1): article no. 7-article no. 7 doi:10.1186/s13046-016-0481-1
  • Zhang W., He K. F., Yang J. G., Ren J. G., Sun Y. F., Zhao J. H., Zhao Y. F.. Infiltration of M2-polarized macrophages in infected lymphatic malformations: possible role in disease progression, British Journal of Dermatology 2016; 175(1): 102-112 doi:10.1111/bjd.14471
  • Gao Lu, Wang Feng qin, Li Hui min, Yang Jie gang, Ren Jian Gang, He Ke fei, Liu Bing, Zhang Wei, Zhao Yi Fang. CCL2/EGF positive feedback loop between cancer cells and macrophages promotes cell migration and invasion in head and neck squamous cell carcinoma, Oncotarget 2016; 7(52): 87037-87051 doi:10.18632/oncotarget.13523

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Professional Societies
  • 01/2023-present: Member of Supervisory Board. Hubei Province(E) Society of Extracellular Vesicles.
  • 01/2021-present: Youth Committee Member. Sinocleft, Chinese Stomatological Association.
  • 01/2020-present: Youth Committee Member. Speech Rehabilitation Professional Committee, Chinese Association of Rehabilitation Medicine.
  • 01/2020-present: Member. Oral Biomedicine Professional Committee, Chinese Stomatological Association.
HKU Committee Appointments
  • 01 August 2024-Present: Faculty of Dentistry, Board of the. The teachers who are members of the Faculty and who are full-time employees of the University

Note

  • All publication and awards data are automatically fetched periodically from the HKU Scholars Hub.